BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

3905 related articles for article (PubMed ID: 26375003)

  • 1. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
    Shi J; Zhao Y; Wang K; Shi X; Wang Y; Huang H; Zhuang Y; Cai T; Wang F; Shao F
    Nature; 2015 Oct; 526(7575):660-5. PubMed ID: 26375003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
    Kayagaki N; Stowe IB; Lee BL; O'Rourke K; Anderson K; Warming S; Cuellar T; Haley B; Roose-Girma M; Phung QT; Liu PS; Lill JR; Li H; Wu J; Kummerfeld S; Zhang J; Lee WP; Snipas SJ; Salvesen GS; Morris LX; Fitzgerald L; Zhang Y; Bertram EM; Goodnow CC; Dixit VM
    Nature; 2015 Oct; 526(7575):666-71. PubMed ID: 26375259
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion.
    He WT; Wan H; Hu L; Chen P; Wang X; Huang Z; Yang ZH; Zhong CQ; Han J
    Cell Res; 2015 Dec; 25(12):1285-98. PubMed ID: 26611636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor.
    Yang J; Liu Z; Wang C; Yang R; Rathkey JK; Pinkard OW; Shi W; Chen Y; Dubyak GR; Abbott DW; Xiao TS
    Proc Natl Acad Sci U S A; 2018 Jun; 115(26):6792-6797. PubMed ID: 29891674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Live-cell visualization of gasdermin D-driven pyroptotic cell death.
    Rathkey JK; Benson BL; Chirieleison SM; Yang J; Xiao TS; Dubyak GR; Huang AY; Abbott DW
    J Biol Chem; 2017 Sep; 292(35):14649-14658. PubMed ID: 28726636
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.
    de Vasconcelos NM; Van Opdenbosch N; Van Gorp H; Martín-Pérez R; Zecchin A; Vandenabeele P; Lamkanfi M
    Cell Rep; 2020 Jul; 32(4):107959. PubMed ID: 32726624
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
    Schneider KS; Groß CJ; Dreier RF; Saller BS; Mishra R; Gorka O; Heilig R; Meunier E; Dick MS; Ćiković T; Sodenkamp J; Médard G; Naumann R; Ruland J; Kuster B; Broz P; Groß O
    Cell Rep; 2017 Dec; 21(13):3846-3859. PubMed ID: 29281832
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inflammatory Caspases: Activation and Cleavage of Gasdermin-D In Vitro and During Pyroptosis.
    Zhao Y; Shi J; Shao F
    Methods Mol Biol; 2018; 1714():131-148. PubMed ID: 29177860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
    Wang K; Sun Q; Zhong X; Zeng M; Zeng H; Shi X; Li Z; Wang Y; Zhao Q; Shao F; Ding J
    Cell; 2020 Mar; 180(5):941-955.e20. PubMed ID: 32109412
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against
    Zhu Q; Zheng M; Balakrishnan A; Karki R; Kanneganti TD
    J Immunol; 2018 Dec; 201(12):3662-3668. PubMed ID: 30404813
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides.
    Russo HM; Rathkey J; Boyd-Tressler A; Katsnelson MA; Abbott DW; Dubyak GR
    J Immunol; 2016 Aug; 197(4):1353-67. PubMed ID: 27385778
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1.
    Ramirez MLG; Poreba M; Snipas SJ; Groborz K; Drag M; Salvesen GS
    J Biol Chem; 2018 May; 293(18):7058-7067. PubMed ID: 29414788
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A bacterial toxin co-opts caspase-3 to disable active gasdermin D and limit macrophage pyroptosis.
    Wright SS; Wang C; Ta A; Havira MS; Ruan J; Rathinam VA; Vanaja SK
    Cell Rep; 2024 Apr; 43(4):114004. PubMed ID: 38522070
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures of the Gasdermin D C-Terminal Domains Reveal Mechanisms of Autoinhibition.
    Liu Z; Wang C; Rathkey JK; Yang J; Dubyak GR; Abbott DW; Xiao TS
    Structure; 2018 May; 26(5):778-784.e3. PubMed ID: 29576317
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATP induces caspase-3/gasdermin E-mediated pyroptosis in NLRP3 pathway-blocked murine macrophages.
    Zeng CY; Li CG; Shu JX; Xu LH; Ouyang DY; Mai FY; Zeng QZ; Zhang CC; Li RM; He XH
    Apoptosis; 2019 Oct; 24(9-10):703-717. PubMed ID: 31175486
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Snapshot of a Deadly Embrace: The Caspase-1-GSDMD Interface.
    Vande Walle L; Lamkanfi M
    Immunity; 2020 Jul; 53(1):6-8. PubMed ID: 32668229
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
    Liu Z; Wang C; Yang J; Zhou B; Yang R; Ramachandran R; Abbott DW; Xiao TS
    Immunity; 2019 Jul; 51(1):43-49.e4. PubMed ID: 31097341
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.
    Platnich JM; Chung H; Lau A; Sandall CF; Bondzi-Simpson A; Chen HM; Komada T; Trotman-Grant AC; Brandelli JR; Chun J; Beck PL; Philpott DJ; Girardin SE; Ho M; Johnson RP; MacDonald JA; Armstrong GD; Muruve DA
    Cell Rep; 2018 Nov; 25(6):1525-1536.e7. PubMed ID: 30404007
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
    Rühl S; Shkarina K; Demarco B; Heilig R; Santos JC; Broz P
    Science; 2018 Nov; 362(6417):956-960. PubMed ID: 30467171
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseases.
    Lu F; Lan Z; Xin Z; He C; Guo Z; Xia X; Hu T
    J Cell Physiol; 2020 Apr; 235(4):3207-3221. PubMed ID: 31621910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 196.