BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1112 related articles for article (PubMed ID: 26375006)

  • 1. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
    Canver MC; Smith EC; Sher F; Pinello L; Sanjana NE; Shalem O; Chen DD; Schupp PG; Vinjamur DS; Garcia SP; Luc S; Kurita R; Nakamura Y; Fujiwara Y; Maeda T; Yuan GC; Zhang F; Orkin SH; Bauer DE
    Nature; 2015 Nov; 527(7577):192-7. PubMed ID: 26375006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
    Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
    Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expanding the Biologist's Toolkit with CRISPR-Cas9.
    Sternberg SH; Doudna JA
    Mol Cell; 2015 May; 58(4):568-74. PubMed ID: 26000842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
    Bauer DE; Kamran SC; Lessard S; Xu J; Fujiwara Y; Lin C; Shao Z; Canver MC; Smith EC; Pinello L; Sabo PJ; Vierstra J; Voit RA; Yuan GC; Porteus MH; Stamatoyannopoulos JA; Lettre G; Orkin SH
    Science; 2013 Oct; 342(6155):253-7. PubMed ID: 24115442
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements.
    Thakore PI; D'Ippolito AM; Song L; Safi A; Shivakumar NK; Kabadi AM; Reddy TE; Crawford GE; Gersbach CA
    Nat Methods; 2015 Dec; 12(12):1143-9. PubMed ID: 26501517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of CRISPR/Cas Genome Editing Technology for Targeted Mutagenesis in Rice.
    Xu R; Wei P; Yang J
    Methods Mol Biol; 2017; 1498():33-40. PubMed ID: 27709567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Strict in vivo specificity of the
    Smith EC; Luc S; Croney DM; Woodworth MB; Greig LC; Fujiwara Y; Nguyen M; Sher F; Macklis JD; Bauer DE; Orkin SH
    Blood; 2016 Nov; 128(19):2338-2342. PubMed ID: 27707736
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
    Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
    Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of stimulation-responsive immune enhancers with CRISPR activation.
    Simeonov DR; Gowen BG; Boontanrart M; Roth TL; Gagnon JD; Mumbach MR; Satpathy AT; Lee Y; Bray NL; Chan AY; Lituiev DS; Nguyen ML; Gate RE; Subramaniam M; Li Z; Woo JM; Mitros T; Ray GJ; Curie GL; Naddaf N; Chu JS; Ma H; Boyer E; Van Gool F; Huang H; Liu R; Tobin VR; Schumann K; Daly MJ; Farh KK; Ansel KM; Ye CJ; Greenleaf WJ; Anderson MS; Bluestone JA; Chang HY; Corn JE; Marson A
    Nature; 2017 Sep; 549(7670):111-115. PubMed ID: 28854172
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Implementation of the CRISPR-Cas9 system in fission yeast.
    Jacobs JZ; Ciccaglione KM; Tournier V; Zaratiegui M
    Nat Commun; 2014 Oct; 5():5344. PubMed ID: 25352017
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
    Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
    Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identifying Novel Enhancer Elements with CRISPR-Based Screens.
    Klein JC; Chen W; Gasperini M; Shendure J
    ACS Chem Biol; 2018 Feb; 13(2):326-332. PubMed ID: 29300083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted genome editing in human cells using CRISPR/Cas nucleases and truncated guide RNAs.
    Fu Y; Reyon D; Joung JK
    Methods Enzymol; 2014; 546():21-45. PubMed ID: 25398334
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells.
    Moorthy SD; Mitchell JA
    J Vis Exp; 2016 Apr; (110):e53552. PubMed ID: 27078492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRISPR-Cas12 and Cas13: the lesser known siblings of CRISPR-Cas9.
    Yan F; Wang W; Zhang J
    Cell Biol Toxicol; 2019 Dec; 35(6):489-492. PubMed ID: 31468291
    [No Abstract]   [Full Text] [Related]  

  • 16. Battling CRISPR-Cas9 off-target genome editing.
    Li D; Zhou H; Zeng X
    Cell Biol Toxicol; 2019 Oct; 35(5):403-406. PubMed ID: 31313008
    [No Abstract]   [Full Text] [Related]  

  • 17. CRISPR/Cas9-Mediated Mutagenesis of Human Pluripotent Stem Cells in Defined Xeno-Free E8 Medium.
    Soh CL; Huangfu D
    Methods Mol Biol; 2017; 1498():57-78. PubMed ID: 27709569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Minimizing off-target effects in CRISPR-Cas9 genome editing.
    Chen SJ
    Cell Biol Toxicol; 2019 Oct; 35(5):399-401. PubMed ID: 31317359
    [No Abstract]   [Full Text] [Related]  

  • 19. The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.
    Huang P; Peslak SA; Lan X; Khandros E; Yano JA; Sharma M; Keller CA; Giardine B; Qin K; Abdulmalik O; Hardison RC; Shi J; Blobel GA
    Blood; 2020 Jun; 135(24):2121-2132. PubMed ID: 32299090
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SeqCor: correct the effect of guide RNA sequences in clustered regularly interspaced short palindromic repeats/Cas9 screening by machine learning algorithm.
    Liu X; Yang Y; Qiu Y; Reyad-Ul-Ferdous M; Ding Q; Wang Y
    J Genet Genomics; 2020 Nov; 47(11):672-680. PubMed ID: 33451939
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 56.