These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

452 related articles for article (PubMed ID: 26384290)

  • 1. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
    Zhang C; Li S; Ji L; Liu S; Li Z; Li S; Meng X
    Bioorg Med Chem Lett; 2015 Oct; 25(20):4693-6. PubMed ID: 26384290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
    J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
    My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
    Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
    Liu W; Zhu L; Guo W; Zhuang C; Zhang Y; Sheng C; Cheng P; Yao J; Wang W; Dong G; Wang S; Miao Z; Zhang W
    Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular modelling design, synthesis and cytotoxic evaluation of certain substituted 2-(3,4,5-triacetoxybenzoylamino)benzo[d]thiazole and 2-(galloylamino)benzo[d]thiazole derivatives having potential topoisomerase-I inhibitory activity.
    Ismail MA; Tratrat C; Haroun MG
    J Enzyme Inhib Med Chem; 2013 Dec; 28(6):1331-45. PubMed ID: 22957723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of lapachol derivatives possessing indole scaffolds as topoisomerase I inhibitors.
    Zhang C; Qu Y; Niu B
    Bioorg Med Chem; 2016 Nov; 24(22):5781-5786. PubMed ID: 27667553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
    Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
    Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
    Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and docking study of new quinoline derivatives as antitumor agents.
    Nasr EE; Mostafa AS; El-Sayed MAA; Massoud MAM
    Arch Pharm (Weinheim); 2019 Jul; 352(7):e1800355. PubMed ID: 31081954
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and evaluation of 4-substituted anthra[2,1-c][1,2,5]thiadiazole-6,11-dione derivatives as novel non-camptothecin topoisomerase I inhibitors.
    Dong G; Fang Y; Liu Y; Liu N; Wu S; Zhang W; Sheng C
    Bioorg Med Chem Lett; 2017 May; 27(9):1929-1933. PubMed ID: 28351590
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study.
    Van HT; Khadka DB; Yang SH; Le TN; Cho SH; Zhao C; Lee IS; Kwon Y; Lee KT; Kim YC; Cho WJ
    Bioorg Med Chem; 2011 Sep; 19(18):5311-20. PubMed ID: 21873069
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling.
    Le TN; Yang SH; Khadka DB; Van HT; Cho SH; Kwon Y; Lee ES; Lee KT; Cho WJ
    Bioorg Med Chem; 2011 Jul; 19(14):4399-404. PubMed ID: 21684168
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
    Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, Molecular Docking and Biological Evaluation of Quinolone Derivatives as Novel Anticancer Agents.
    Li J; Zheng TC; Jin Y; Xu JG; Yu JG; Lv YW
    Chem Pharm Bull (Tokyo); 2018 Jan; 66(1):55-60. PubMed ID: 29118308
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies.
    Kadagathur M; Devi GP; Grewal P; Sigalapalli DK; Makhal PN; Banerjee UC; Bathini NB; Tangellamudi ND
    Bioorg Chem; 2020 Jun; 99():103629. PubMed ID: 32272367
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L; Marzaro G; Ferrarese A; Gia O; Chilin A
    Eur J Med Chem; 2014 Apr; 77():103-9. PubMed ID: 24631729
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pyridazino[1,6-b]quinazolinones as new anticancer scaffold: Synthesis, DNA intercalation, topoisomerase I inhibition and antitumor evaluation in vitro and in vivo.
    Huang WY; Zhang XR; Lyu L; Wang SQ; Zhang XT
    Bioorg Chem; 2020 Jun; 99():103814. PubMed ID: 32278208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel securinine derivatives as topoisomerase I based antitumor agents.
    Hou W; Wang ZY; Peng CK; Lin J; Liu X; Chang YQ; Xu J; Jiang RW; Lin H; Sun PH; Chen WM
    Eur J Med Chem; 2016 Oct; 122():149-163. PubMed ID: 27344492
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.
    Zhao Q; Xu X; Xie Z; Liu X; You Q; Guo Q; Zhong Y; Li Z
    Bioorg Med Chem Lett; 2016 Feb; 26(3):1068-1072. PubMed ID: 26725027
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles.
    Singh M; Tandon V
    Eur J Med Chem; 2011 Feb; 46(2):659-69. PubMed ID: 21186067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.