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2. Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations. Harada Y; Harada H J Cell Physiol; 2009 Jul; 220(1):16-20. PubMed ID: 19334039 [TBL] [Abstract][Full Text] [Related]
3. AML1 mutations induced MDS and MDS/AML in a mouse BMT model. Watanabe-Okochi N; Kitaura J; Ono R; Harada H; Harada Y; Komeno Y; Nakajima H; Nosaka T; Inaba T; Kitamura T Blood; 2008 Apr; 111(8):4297-308. PubMed ID: 18192504 [TBL] [Abstract][Full Text] [Related]
4. Hyperactivation of the RAS signaling pathway in myelodysplastic syndrome with AML1/RUNX1 point mutations. Niimi H; Harada H; Harada Y; Ding Y; Imagawa J; Inaba T; Kyo T; Kimura A Leukemia; 2006 Apr; 20(4):635-44. PubMed ID: 16467864 [TBL] [Abstract][Full Text] [Related]
5. Molecular mechanisms that produce secondary MDS/AML by RUNX1/AML1 point mutations. Harada Y; Harada H J Cell Biochem; 2011 Feb; 112(2):425-32. PubMed ID: 21268063 [TBL] [Abstract][Full Text] [Related]
6. RUNX1/AML1 mutant collaborates with BMI1 overexpression in the development of human and murine myelodysplastic syndromes. Harada Y; Inoue D; Ding Y; Imagawa J; Doki N; Matsui H; Yahata T; Matsushita H; Ando K; Sashida G; Iwama A; Kitamura T; Harada H Blood; 2013 Apr; 121(17):3434-46. PubMed ID: 23471304 [TBL] [Abstract][Full Text] [Related]
7. AML1/RUNX1 gene point mutations in childhood myeloid malignancies. Migas A; Savva N; Mishkova O; Aleinikova OV Pediatr Blood Cancer; 2011 Oct; 57(4):583-7. PubMed ID: 21294243 [TBL] [Abstract][Full Text] [Related]
8. Point mutations in the AML1/RUNX1 gene associated with myelodysplastic syndrome. Harada H; Harada Y Crit Rev Eukaryot Gene Expr; 2005; 15(3):183-96. PubMed ID: 16390315 [TBL] [Abstract][Full Text] [Related]
9. [Distinct genetic pathway in the molecular pathogenesis of MDS/AML with AML1/RUNX1 point mutations]. Harada H Rinsho Ketsueki; 2007 Jul; 48(7):541-6. PubMed ID: 17695302 [No Abstract] [Full Text] [Related]
10. C-terminal mutation of RUNX1 attenuates the DNA-damage repair response in hematopoietic stem cells. Satoh Y; Matsumura I; Tanaka H; Harada H; Harada Y; Matsui K; Shibata M; Mizuki M; Kanakura Y Leukemia; 2012 Feb; 26(2):303-11. PubMed ID: 21836608 [TBL] [Abstract][Full Text] [Related]
11. ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events. Haferlach C; Bacher U; Schnittger S; Alpermann T; Zenger M; Kern W; Haferlach T Genes Chromosomes Cancer; 2012 Apr; 51(4):328-37. PubMed ID: 22162288 [TBL] [Abstract][Full Text] [Related]
12. Biological Activities of RUNX1 Mutants Predict Secondary Acute Leukemia Transformation from Chronic Myelomonocytic Leukemia and Myelodysplastic Syndromes. Tsai SC; Shih LY; Liang ST; Huang YJ; Kuo MC; Huang CF; Shih YS; Lin TH; Chiu MC; Liang DC Clin Cancer Res; 2015 Aug; 21(15):3541-51. PubMed ID: 25840971 [TBL] [Abstract][Full Text] [Related]
14. Implications of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome (MDS): future molecular therapeutic directions for MDS. Harada H; Harada Y; Kimura A Curr Cancer Drug Targets; 2006 Sep; 6(6):553-65. PubMed ID: 17017876 [TBL] [Abstract][Full Text] [Related]
15. Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome. Matsuura S; Komeno Y; Stevenson KE; Biggs JR; Lam K; Tang T; Lo MC; Cong X; Yan M; Neuberg DS; Zhang DE Blood; 2012 Nov; 120(19):4028-37. PubMed ID: 22919028 [TBL] [Abstract][Full Text] [Related]
16. Genetic predisposition syndromes: when should they be considered in the work-up of MDS? Babushok DV; Bessler M Best Pract Res Clin Haematol; 2015 Mar; 28(1):55-68. PubMed ID: 25659730 [TBL] [Abstract][Full Text] [Related]
17. [Research progress on mechanism of MDS transformation into AML]. Wang LL; Gao C; Chen BA Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2011 Feb; 19(1):254-9. PubMed ID: 21362264 [TBL] [Abstract][Full Text] [Related]
18. Molecular characterisation of a recurrent, semi-cryptic RUNX1 translocation t(7;21) in myelodysplastic syndrome and acute myeloid leukaemia. Foster N; Paulsson K; Sales M; Cunningham J; Groves M; O'Connor N; Begum S; Stubbs T; McMullan DJ; Griffiths M; Pratt N; Tauro S Br J Haematol; 2010 Mar; 148(6):938-43. PubMed ID: 20064152 [TBL] [Abstract][Full Text] [Related]
20. Genetic predisposition to myelodysplastic syndrome and acute myeloid leukemia in children and young adults. Babushok DV; Bessler M; Olson TS Leuk Lymphoma; 2016; 57(3):520-36. PubMed ID: 26693794 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]