BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 26387955)

  • 1. Amino Acids Stimulate TORC1 through Lst4-Lst7, a GTPase-Activating Protein Complex for the Rag Family GTPase Gtr2.
    Péli-Gulli MP; Sardu A; Panchaud N; Raucci S; De Virgilio C
    Cell Rep; 2015 Oct; 13(1):1-7. PubMed ID: 26387955
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Feedback Inhibition of the Rag GTPase GAP Complex Lst4-Lst7 Safeguards TORC1 from Hyperactivation by Amino Acid Signals.
    Péli-Gulli MP; Raucci S; Hu Z; Dengjel J; De Virgilio C
    Cell Rep; 2017 Jul; 20(2):281-288. PubMed ID: 28700931
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amino acid deprivation inhibits TORC1 through a GTPase-activating protein complex for the Rag family GTPase Gtr1.
    Panchaud N; Péli-Gulli MP; De Virgilio C
    Sci Signal; 2013 May; 6(277):ra42. PubMed ID: 23716719
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dynamic relocation of the TORC1-Gtr1/2-Ego1/2/3 complex is regulated by Gtr1 and Gtr2.
    Kira S; Kumano Y; Ukai H; Takeda E; Matsuura A; Noda T
    Mol Biol Cell; 2016 Jan; 27(2):382-96. PubMed ID: 26609069
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Vam6 GEF controls TORC1 by activating the EGO complex.
    Binda M; Péli-Gulli MP; Bonfils G; Panchaud N; Urban J; Sturgill TW; Loewith R; De Virgilio C
    Mol Cell; 2009 Sep; 35(5):563-73. PubMed ID: 19748353
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unsolved mysteries of Rag GTPase signaling in yeast.
    Hatakeyama R; De Virgilio C
    Small GTPases; 2016 Oct; 7(4):239-246. PubMed ID: 27400376
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases.
    Chia KH; Fukuda T; Sofyantoro F; Matsuda T; Amai T; Shiozaki K
    Elife; 2017 Dec; 6():. PubMed ID: 29199950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ivy1 is a negative regulator of Gtr-dependent TORC1 activation.
    Varlakhanova NV; Tornabene BA; Ford MGJ
    J Cell Sci; 2018 Sep; 131(17):. PubMed ID: 30097557
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reciprocal conversion of Gtr1 and Gtr2 nucleotide-binding states by Npr2-Npr3 inactivates TORC1 and induces autophagy.
    Kira S; Tabata K; Shirahama-Noda K; Nozoe A; Yoshimori T; Noda T
    Autophagy; 2014 Sep; 10(9):1565-78. PubMed ID: 25046117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gtr/Ego-independent TORC1 activation is achieved through a glutamine-sensitive interaction with Pib2 on the vacuolar membrane.
    Ukai H; Araki Y; Kira S; Oikawa Y; May AI; Noda T
    PLoS Genet; 2018 Apr; 14(4):e1007334. PubMed ID: 29698392
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast.
    Ma N; Ma Y; Nakashima A; Kikkawa U; Furuyashiki T
    PLoS One; 2016; 11(5):e0156239. PubMed ID: 27227887
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nitrogen source activates TOR (target of rapamycin) complex 1 via glutamine and independently of Gtr/Rag proteins.
    Stracka D; Jozefczuk S; Rudroff F; Sauer U; Hall MN
    J Biol Chem; 2014 Sep; 289(36):25010-20. PubMed ID: 25063813
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Crystal structure of the Ego1-Ego2-Ego3 complex and its role in promoting Rag GTPase-dependent TORC1 signaling.
    Powis K; Zhang T; Panchaud N; Wang R; De Virgilio C; Ding J
    Cell Res; 2015 Sep; 25(9):1043-59. PubMed ID: 26206314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ego3 functions as a homodimer to mediate the interaction between Gtr1-Gtr2 and Ego1 in the ego complex to activate TORC1.
    Zhang T; Péli-Gulli MP; Yang H; De Virgilio C; Ding J
    Structure; 2012 Dec; 20(12):2151-60. PubMed ID: 23123112
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endolysosomal membrane trafficking complexes drive nutrient-dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae.
    Kingsbury JM; Sen ND; Maeda T; Heitman J; Cardenas ME
    Genetics; 2014 Apr; 196(4):1077-89. PubMed ID: 24514902
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An
    Tanigawa M; Maeda T
    Mol Cell Biol; 2017 Jul; 37(14):. PubMed ID: 28483912
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.
    Shen K; Sabatini DM
    Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9545-9550. PubMed ID: 30181260
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SEACing the GAP that nEGOCiates TORC1 activation: evolutionary conservation of Rag GTPase regulation.
    Panchaud N; Péli-Gulli MP; De Virgilio C
    Cell Cycle; 2013 Sep; 12(18):2948-52. PubMed ID: 23974112
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast.
    Valbuena N; Guan KL; Moreno S
    J Cell Sci; 2012 Apr; 125(Pt 8):1920-8. PubMed ID: 22344254
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
    Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
    Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.