BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 26388427)

  • 1. TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation.
    Thoppil RJ; Adapala RK; Cappelli HC; Kondeti V; Dudley AC; Gary Meszaros J; Paruchuri S; Thodeti CK
    Sci Rep; 2015 Sep; 5():14257. PubMed ID: 26388427
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy.
    Adapala RK; Thoppil RJ; Ghosh K; Cappelli HC; Dudley AC; Paruchuri S; Keshamouni V; Klagsbrun M; Meszaros JG; Chilian WM; Ingber DE; Thodeti CK
    Oncogene; 2016 Jan; 35(3):314-22. PubMed ID: 25867067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway.
    Thoppil RJ; Cappelli HC; Adapala RK; Kanugula AK; Paruchuri S; Thodeti CK
    Oncotarget; 2016 May; 7(18):25849-61. PubMed ID: 27029071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A functional transient receptor potential vanilloid 4 (TRPV4) channel is expressed in human endothelial progenitor cells.
    Dragoni S; Guerra G; Fiorio Pla A; Bertoni G; Rappa A; Poletto V; Bottino C; Aronica A; Lodola F; Cinelli MP; Laforenza U; Rosti V; Tanzi F; Munaron L; Moccia F
    J Cell Physiol; 2015 Jan; 230(1):95-104. PubMed ID: 24911002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TRPV4 regulates insulin mRNA expression and INS-1E cell death via ERK1/2 and NO-dependent mechanisms.
    Billert M; Skrzypski M; Sassek M; Szczepankiewicz D; Wojciechowicz T; Mergler S; Strowski MZ; Nowak KW
    Cell Signal; 2017 Jul; 35():242-249. PubMed ID: 28359774
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel noncanonical regulation of soluble VEGF/VEGFR2 signaling by mechanosensitive ion channel TRPV4.
    Kanugula AK; Adapala RK; Midha P; Cappelli HC; Meszaros JG; Paruchuri S; Chilian WM; Thodeti CK
    FASEB J; 2019 Jan; 33(1):195-203. PubMed ID: 29957061
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro-inflammatory phenotype.
    Beddek K; Raffin F; Borgel D; Saller F; Riccobono D; Bobe R; Boittin FX
    Physiol Rep; 2021 Feb; 9(3):e14613. PubMed ID: 33512067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis.
    Xu S; Liu B; Yin M; Koroleva M; Mastrangelo M; Ture S; Morrell CN; Zhang DX; Fisher EA; Jin ZG
    Oncotarget; 2016 Jun; 7(25):37622-37635. PubMed ID: 27191895
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytes.
    Olivan-Viguera A; Garcia-Otin AL; Lozano-Gerona J; Abarca-Lachen E; Garcia-Malinis AJ; Hamilton KL; Gilaberte Y; Pueyo E; Köhler R
    PLoS One; 2018; 13(1):e0190307. PubMed ID: 29293584
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways.
    Jie P; Hong Z; Tian Y; Li Y; Lin L; Zhou L; Du Y; Chen L; Chen L
    Cell Death Dis; 2015 Jun; 6(6):e1775. PubMed ID: 26043075
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanosensitive TRPV4 channels stabilize VE-cadherin junctions to regulate tumor vascular integrity and metastasis.
    Cappelli HC; Kanugula AK; Adapala RK; Amin V; Sharma P; Midha P; Paruchuri S; Thodeti CK
    Cancer Lett; 2019 Feb; 442():15-20. PubMed ID: 30401632
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells.
    Peters AA; Jamaludin SYN; Yapa KTDS; Chalmers S; Wiegmans AP; Lim HF; Milevskiy MJG; Azimi I; Davis FM; Northwood KS; Pera E; Marcial DL; Dray E; Waterhouse NJ; Cabot PJ; Gonda TJ; Kenny PA; Brown MA; Khanna KK; Roberts-Thomson SJ; Monteith GR
    Oncogene; 2017 Nov; 36(46):6490-6500. PubMed ID: 28759041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I.
    Thorneloe KS; Sulpizio AC; Lin Z; Figueroa DJ; Clouse AK; McCafferty GP; Chendrimada TP; Lashinger ES; Gordon E; Evans L; Misajet BA; Demarini DJ; Nation JH; Casillas LN; Marquis RW; Votta BJ; Sheardown SA; Xu X; Brooks DP; Laping NJ; Westfall TD
    J Pharmacol Exp Ther; 2008 Aug; 326(2):432-42. PubMed ID: 18499743
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cells.
    Mergler S; Valtink M; Taetz K; Sahlmüller M; Fels G; Reinach PS; Engelmann K; Pleyer U
    Exp Eye Res; 2011 Nov; 93(5):710-9. PubMed ID: 21996372
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells.
    Sullivan MN; Francis M; Pitts NL; Taylor MS; Earley S
    Mol Pharmacol; 2012 Sep; 82(3):464-72. PubMed ID: 22689561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Opposing actions of TRPV4 channel activation in the lung vasculature.
    Ke SK; Chen L; Duan HB; Tu YR
    Respir Physiol Neurobiol; 2015 Dec; 219():43-50. PubMed ID: 26282788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular and functional characterization of TRPV4 channels in pregnant and nonpregnant mouse uterus.
    Singh V; Ram M; Kandasamy K; Thangamalai R; Choudhary S; Dash JR; Kumar D; Parida S; Singh TU; Mishra SK
    Life Sci; 2015 Feb; 122():51-8. PubMed ID: 25529150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TRPV4 partially participates in proliferation of human brain capillary endothelial cells.
    Hatano N; Suzuki H; Itoh Y; Muraki K
    Life Sci; 2013 Mar; 92(4-5):317-24. PubMed ID: 23333822
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity.
    Kanugula AK; Adapala RK; Jamaiyar A; Lenkey N; Guarino BD; Liedtke W; Yin L; Paruchuri S; Thodeti CK
    Angiogenesis; 2021 Aug; 24(3):647-656. PubMed ID: 33656628
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers.
    Mukaiyama M; Yamasaki Y; Usui T; Nagumo Y
    FEBS Lett; 2019 Aug; 593(16):2250-2260. PubMed ID: 31206656
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.