BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 26390015)

  • 1. Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation.
    Wang Z; Bhattacharya A; Ivanov DN
    PLoS One; 2015; 10(9):e0138780. PubMed ID: 26390015
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.
    Wu X; Lan L; Wilson DM; Marquez RT; Tsao WC; Gao P; Roy A; Turner BA; McDonald P; Tunge JA; Rogers SA; Dixon DA; Aubé J; Xu L
    ACS Chem Biol; 2015 Jun; 10(6):1476-84. PubMed ID: 25750985
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro.
    Kaur K; Wu X; Fields JK; Johnson DK; Lan L; Pratt M; Somoza AD; Wang CCC; Karanicolas J; Oakley BR; Xu L; De Guzman RN
    PLoS One; 2017; 12(4):e0175471. PubMed ID: 28414767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets.
    Scheiba RM; de Opakua AI; Díaz-Quintana A; Cruz-Gallardo I; Martínez-Cruz LA; Martínez-Chantar ML; Blanco FJ; Díaz-Moreno I
    RNA Biol; 2014; 11(10):1250-61. PubMed ID: 25584704
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of HuR structure and function by dihydrotanshinone-I.
    Lal P; Cerofolini L; D'Agostino VG; Zucal C; Fuccio C; Bonomo I; Dassi E; Giuntini S; Di Maio D; Vishwakarma V; Preet R; Williams SN; Fairlamb MS; Munk R; Lehrmann E; Abdelmohsen K; Elezgarai SR; Luchinat C; Novellino E; Quattrone A; Biasini E; Manzoni L; Gorospe M; Dixon DA; Seneci P; Marinelli L; Fragai M; Provenzani A
    Nucleic Acids Res; 2017 Sep; 45(16):9514-9527. PubMed ID: 28934484
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM.
    Ripin N; Boudet J; Duszczyk MM; Hinniger A; Faller M; Krepl M; Gadi A; Schneider RJ; Šponer J; Meisner-Kober NC; Allain FH
    Proc Natl Acad Sci U S A; 2019 Feb; 116(8):2935-2944. PubMed ID: 30718402
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel high throughput biochemical assay to evaluate the HuR protein-RNA complex formation.
    D'Agostino VG; Adami V; Provenzani A
    PLoS One; 2013; 8(8):e72426. PubMed ID: 23951323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
    Pabis M; Popowicz GM; Stehle R; Fernández-Ramos D; Asami S; Warner L; García-Mauriño SM; Schlundt A; Martínez-Chantar ML; Díaz-Moreno I; Sattler M
    Nucleic Acids Res; 2019 Jan; 47(2):1011-1029. PubMed ID: 30418581
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors.
    Manzoni L; Zucal C; Maio DD; D'Agostino VG; Thongon N; Bonomo I; Lal P; Miceli M; Baj V; Brambilla M; Cerofolini L; Elezgarai S; Biasini E; Luchinat C; Novellino E; Fragai M; Marinelli L; Provenzani A; Seneci P
    J Med Chem; 2018 Feb; 61(4):1483-1498. PubMed ID: 29313684
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of a high-throughput fluorescence polarization DNA cleavage assay for the identification of FEN1 inhibitors.
    McWhirter C; Tonge M; Plant H; Hardern I; Nissink W; Durant ST
    J Biomol Screen; 2013 Jun; 18(5):567-75. PubMed ID: 23427045
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The identification of novel small-molecule inhibitors targeting WDR5-MLL1 interaction through fluorescence polarization based high-throughput screening.
    Ye X; Zhang R; Lian F; Zhang W; Lu W; Han J; Zhang N; Jin J; Luo C; Chen K; Ye F; Ding H
    Bioorg Med Chem Lett; 2019 Feb; 29(4):638-645. PubMed ID: 30626558
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution.
    Lixa C; Mujo A; de Magalhães MTQ; Almeida FCL; Lima LMTR; Pinheiro AS
    J Biomol NMR; 2018 Dec; 72(3-4):179-192. PubMed ID: 30535889
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A dual-readout F2 assay that combines fluorescence resonance energy transfer and fluorescence polarization for monitoring bimolecular interactions.
    Du Y; Nikolovska-Coleska Z; Qui M; Li L; Lewis I; Dingledine R; Stuckey JA; Krajewski K; Roller PP; Wang S; Fu H
    Assay Drug Dev Technol; 2011 Aug; 9(4):382-93. PubMed ID: 21395401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells.
    Sommer G; Fedarovich A; Kota V; Rodriguez R; Smith CD; Heise T
    PLoS One; 2017; 12(3):e0173246. PubMed ID: 28291789
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of a high-throughput fluorescence polarization assay to identify novel ligands of glutamate carboxypeptidase II.
    Alquicer G; Sedlák D; Byun Y; Pavlícek J; Stathis M; Rojas C; Slusher B; Pomper MG; Bartunek P; Barinka C
    J Biomol Screen; 2012 Sep; 17(8):1030-40. PubMed ID: 22751730
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High-throughput fluorescence polarization assay for chemical library screening against anti-apoptotic Bcl-2 family member Bfl-1.
    Zhai D; Godoi P; Sergienko E; Dahl R; Chan X; Brown B; Rascon J; Hurder A; Su Y; Chung TD; Jin C; Diaz P; Reed JC
    J Biomol Screen; 2012 Mar; 17(3):350-60. PubMed ID: 22156224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A fluorescent-based high-throughput screening assay for small molecules that inhibit the interaction of MdmX with p53.
    Tsuganezawa K; Nakagawa Y; Kato M; Taruya S; Takahashi F; Endoh M; Utata R; Mori M; Ogawa N; Honma T; Yokoyama S; Hashizume Y; Aoki M; Kasai T; Kigawa T; Kojima H; Okabe T; Nagano T; Tanaka A
    J Biomol Screen; 2013 Feb; 18(2):191-8. PubMed ID: 22989451
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel indole derivatives targeting HuR-mRNA complex to counteract high glucose damage in retinal endothelial cells.
    Platania CBM; Pittalà V; Pascale A; Marchesi N; Anfuso CD; Lupo G; Cristaldi M; Olivieri M; Lazzara F; Di Paola L; Drago F; Bucolo C
    Biochem Pharmacol; 2020 May; 175():113908. PubMed ID: 32171729
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90.
    Riccardi Sirtori F; Caronni D; Colombo M; Dalvit C; Paolucci M; Regazzoni L; Visco C; Fogliatto G
    Eur J Pharm Sci; 2015 Aug; 76():83-94. PubMed ID: 25952103
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-throughput fluorescence anisotropy screen for inhibitors of the oncogenic mRNA binding protein, IMP-1.
    Mahapatra L; Mao C; Andruska N; Zhang C; Shapiro DJ
    J Biomol Screen; 2014 Mar; 19(3):427-36. PubMed ID: 24108120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.