190 related articles for article (PubMed ID: 26393293)
21. Fetal hemoglobin in sickle cell anemia: molecular characterization of the unusually high fetal hemoglobin phenotype in African Americans.
Akinsheye I; Solovieff N; Ngo D; Malek A; Sebastiani P; Steinberg MH; Chui DH
Am J Hematol; 2012 Feb; 87(2):217-9. PubMed ID: 22139998
[TBL] [Abstract][Full Text] [Related]
22. The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria.
Ojewunmi OO; Adeyemo TA; Oyetunji AI; Inyang B; Akinrindoye A; Mkumbe BS; Gardner K; Rooks H; Brewin J; Patel H; Lee SH; Chung R; Rashkin S; Kang G; Chianumba R; Sangeda R; Mwita L; Isa H; Agumadu UN; Ekong R; Faruk JA; Jamoh BY; Adebiyi NM; Umar IA; Hassan A; Grace C; Goel A; Inusa BPD; Falchi M; Nkya S; Makani J; Ahmad HR; Nnodu O; Strouboulis J; Menzel S
Hum Mol Genet; 2024 May; 33(10):919-929. PubMed ID: 38339995
[TBL] [Abstract][Full Text] [Related]
23. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
24. Fetal hemoglobin regulating genetic variants identified in homozygous (HbSS) and heterozygous (HbSA) subjects from South Mexico.
Rizo-de la Torre LC; Borrayo-López FJ; Perea-Díaz FJ; Aquino E; Venegas M; Hernández-Carbajal C; Espinoza-Mata LL; Ibarra-Cortés B
J Trop Pediatr; 2022 Aug; 68(5):. PubMed ID: 36130307
[TBL] [Abstract][Full Text] [Related]
25. Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans.
Bae HT; Baldwin CT; Sebastiani P; Telen MJ; Ashley-Koch A; Garrett M; Hooper WC; Bean CJ; Debaun MR; Arking DE; Bhatnagar P; Casella JF; Keefer JR; Barron-Casella E; Gordeuk V; Kato GJ; Minniti C; Taylor J; Campbell A; Luchtman-Jones L; Hoppe C; Gladwin MT; Zhang Y; Steinberg MH
Blood; 2012 Aug; 120(9):1961-2. PubMed ID: 22936743
[No Abstract] [Full Text] [Related]
26. Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Wu Y; Zeng J; Roscoe BP; Liu P; Yao Q; Lazzarotto CR; Clement K; Cole MA; Luk K; Baricordi C; Shen AH; Ren C; Esrick EB; Manis JP; Dorfman DM; Williams DA; Biffi A; Brugnara C; Biasco L; Brendel C; Pinello L; Tsai SQ; Wolfe SA; Bauer DE
Nat Med; 2019 May; 25(5):776-783. PubMed ID: 30911135
[TBL] [Abstract][Full Text] [Related]
27. Genetic modifiers of HbF and response to hydroxyurea in sickle cell disease.
Green NS; Barral S
Pediatr Blood Cancer; 2011 Feb; 56(2):177-81. PubMed ID: 20830771
[TBL] [Abstract][Full Text] [Related]
28. 2p15-p16.1 microdeletions encompassing and proximal to BCL11A are associated with elevated HbF in addition to neurologic impairment.
Funnell AP; Prontera P; Ottaviani V; Piccione M; Giambona A; Maggio A; Ciaffoni F; Stehling-Sun S; Marra M; Masiello F; Varricchio L; Stamatoyannopoulos JA; Migliaccio AR; Papayannopoulou T
Blood; 2015 Jul; 126(1):89-93. PubMed ID: 26019277
[TBL] [Abstract][Full Text] [Related]
29. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies.
Sedgewick AE; Timofeev N; Sebastiani P; So JCC; Ma ESK; Chan LC; Fucharoen G; Fucharoen S; Barbosa CG; Vardarajan BN; Farrer LA; Baldwin CT; Steinberg MH; Chui DHK
Blood Cells Mol Dis; 2008; 41(3):255-258. PubMed ID: 18691915
[TBL] [Abstract][Full Text] [Related]
30. Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea.
Allard P; Alhaj N; Lobitz S; Cario H; Jarisch A; Grosse R; Oevermann L; Hakimeh D; Tagliaferri L; Kohne E; Kopp-Schneider A; Kulozik AE; Kunz JB
Haematologica; 2022 Jul; 107(7):1577-1588. PubMed ID: 34706496
[TBL] [Abstract][Full Text] [Related]
31. BCL11A deletions result in fetal hemoglobin persistence and neurodevelopmental alterations.
Basak A; Hancarova M; Ulirsch JC; Balci TB; Trkova M; Pelisek M; Vlckova M; Muzikova K; Cermak J; Trka J; Dyment DA; Orkin SH; Daly MJ; Sedlacek Z; Sankaran VG
J Clin Invest; 2015 Jun; 125(6):2363-8. PubMed ID: 25938782
[TBL] [Abstract][Full Text] [Related]
32. Genetic variants at HbF-modifier loci moderate anemia and leukocytosis in sickle cell disease in Tanzania.
Mtatiro SN; Makani J; Mmbando B; Thein SL; Menzel S; Cox SE
Am J Hematol; 2015 Jan; 90(1):E1-4. PubMed ID: 25263325
[TBL] [Abstract][Full Text] [Related]
33. Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
Uda M; Galanello R; Sanna S; Lettre G; Sankaran VG; Chen W; Usala G; Busonero F; Maschio A; Albai G; Piras MG; Sestu N; Lai S; Dei M; Mulas A; Crisponi L; Naitza S; Asunis I; Deiana M; Nagaraja R; Perseu L; Satta S; Cipollina MD; Sollaino C; Moi P; Hirschhorn JN; Orkin SH; Abecasis GR; Schlessinger D; Cao A
Proc Natl Acad Sci U S A; 2008 Feb; 105(5):1620-5. PubMed ID: 18245381
[TBL] [Abstract][Full Text] [Related]
34. Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells.
Zhang Y; Paikari A; Sumazin P; Ginter Summarell CC; Crosby JR; Boerwinkle E; Weiss MJ; Sheehan VA
Blood; 2018 Jul; 132(3):321-333. PubMed ID: 29884740
[TBL] [Abstract][Full Text] [Related]
35. Polymorphic variations influencing fetal hemoglobin levels: association study in beta-thalassemia carriers and in normal individuals of Portuguese origin.
Pereira C; Relvas L; Bento C; Abade A; Ribeiro ML; Manco L
Blood Cells Mol Dis; 2015 Apr; 54(4):315-20. PubMed ID: 25842369
[TBL] [Abstract][Full Text] [Related]
36. Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania.
Nkya S; Mwita L; Mgaya J; Kumburu H; van Zwetselaar M; Menzel S; Mazandu GK; Sangeda R; Chimusa E; Makani J
BMC Med Genet; 2020 Jun; 21(1):125. PubMed ID: 32503527
[TBL] [Abstract][Full Text] [Related]
37. Fetal hemoglobin modulates neurocognitive performance in sickle cell anemia
Heitzer AM; Longoria J; Rampersaud E; Rashkin SR; Estepp JH; Okhomina VI; Wang WC; Raches D; Potter B; Steinberg MH; King AA; Kang G; Hankins JS
Curr Res Transl Med; 2022 Jul; 70(3):103335. PubMed ID: 35303690
[TBL] [Abstract][Full Text] [Related]
38.
Gardner K; Fulford T; Silver N; Rooks H; Angelis N; Allman M; Nkya S; Makani J; Howard J; Kesse-Adu R; Rees DC; Stuart-Smith S; Yeghen T; Awogbade M; Sangeda RZ; Mgaya J; Patel H; Newhouse S; Menzel S; Thein SL
Blood Adv; 2018 Feb; 2(3):235-239. PubMed ID: 29437638
[TBL] [Abstract][Full Text] [Related]
39. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.
Grevet JD; Lan X; Hamagami N; Edwards CR; Sankaranarayanan L; Ji X; Bhardwaj SK; Face CJ; Posocco DF; Abdulmalik O; Keller CA; Giardine B; Sidoli S; Garcia BA; Chou ST; Liebhaber SA; Hardison RC; Shi J; Blobel GA
Science; 2018 Jul; 361(6399):285-290. PubMed ID: 30026227
[TBL] [Abstract][Full Text] [Related]
40. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Bauer DE; Kamran SC; Lessard S; Xu J; Fujiwara Y; Lin C; Shao Z; Canver MC; Smith EC; Pinello L; Sabo PJ; Vierstra J; Voit RA; Yuan GC; Porteus MH; Stamatoyannopoulos JA; Lettre G; Orkin SH
Science; 2013 Oct; 342(6155):253-7. PubMed ID: 24115442
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]