These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 26393419)

  • 1. A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction.
    Pronobis MI; Rusan NM; Peifer M
    Elife; 2015 Sep; 4():e08022. PubMed ID: 26393419
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reconstituting regulation of the canonical Wnt pathway by engineering a minimal β-catenin destruction machine.
    Pronobis MI; Deuitch N; Posham V; Mimori-Kiyosue Y; Peifer M
    Mol Biol Cell; 2017 Jan; 28(1):41-53. PubMed ID: 27852897
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversible modification of adenomatous polyposis coli (APC) with K63-linked polyubiquitin regulates the assembly and activity of the β-catenin destruction complex.
    Tran H; Polakis P
    J Biol Chem; 2012 Aug; 287(34):28552-63. PubMed ID: 22761442
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysing the impact of nucleo-cytoplasmic shuttling of β-catenin and its antagonists APC, Axin and GSK3 on Wnt/β-catenin signalling.
    Schmitz Y; Rateitschak K; Wolkenhauer O
    Cell Signal; 2013 Nov; 25(11):2210-21. PubMed ID: 23872074
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC.
    Tacchelly-Benites O; Wang Z; Yang E; Benchabane H; Tian A; Randall MP; Ahmed Y
    PLoS Genet; 2018 Feb; 14(2):e1007178. PubMed ID: 29408853
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity.
    Valvezan AJ; Zhang F; Diehl JA; Klein PS
    J Biol Chem; 2012 Feb; 287(6):3823-32. PubMed ID: 22184111
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thr160 of Axin1 is critical for the formation and function of the β-catenin destruction complex.
    Koyama-Nasu R; Hayashi T; Nasu-Nishimura Y; Akiyama T; Yamanaka R
    Biochem Biophys Res Commun; 2015 Apr; 459(3):411-5. PubMed ID: 25735981
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling.
    Roberts DM; Pronobis MI; Poulton JS; Waldmann JD; Stephenson EM; Hanna S; Peifer M
    Mol Biol Cell; 2011 Jun; 22(11):1845-63. PubMed ID: 21471006
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction.
    Ji L; Lu B; Wang Z; Yang Z; Reece-Hoyes J; Russ C; Xu W; Cong F
    Mol Cell; 2018 Oct; 72(1):37-47.e4. PubMed ID: 30197296
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Poly(ADP-ribose) Polymerase Enzyme Tankyrase Antagonizes Activity of the β-Catenin Destruction Complex through ADP-ribosylation of Axin and APC2.
    Croy HE; Fuller CN; Giannotti J; Robinson P; Foley AVA; Yamulla RJ; Cosgriff S; Greaves BD; von Kleeck RA; An HH; Powers CM; Tran JK; Tocker AM; Jacob KD; Davis BK; Roberts DM
    J Biol Chem; 2016 Jun; 291(24):12747-12760. PubMed ID: 27068743
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
    Wang Z; Tacchelly-Benites O; Yang E; Thorne CA; Nojima H; Lee E; Ahmed Y
    Genetics; 2016 May; 203(1):269-81. PubMed ID: 26975665
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation.
    Ranes M; Zaleska M; Sakalas S; Knight R; Guettler S
    Mol Cell; 2021 Aug; 81(16):3246-3261.e11. PubMed ID: 34352208
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo.
    Schaefer KN; Bonello TT; Zhang S; Williams CE; Roberts DM; McKay DJ; Peifer M
    PLoS Genet; 2018 Apr; 14(4):e1007339. PubMed ID: 29641560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
    Lin Y; Ohkawara B; Ito M; Misawa N; Miyamoto K; Takegami Y; Masuda A; Toyokuni S; Ohno K
    Sci Rep; 2016 Aug; 6():31986. PubMed ID: 27558955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta.
    Hart MJ; de los Santos R; Albert IN; Rubinfeld B; Polakis P
    Curr Biol; 1998 May; 8(10):573-81. PubMed ID: 9601641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.
    Tran H; Bustos D; Yeh R; Rubinfeld B; Lam C; Shriver S; Zilberleyb I; Lee MW; Phu L; Sarkar AA; Zohn IE; Wertz IE; Kirkpatrick DS; Polakis P
    J Biol Chem; 2013 Feb; 288(6):3753-67. PubMed ID: 23277359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation.
    Zhang D; Ni QQ; Wang SY; He WF; Hong ZX; Liu HY; Chen XH; Chen LJ; Han FY; Zhang LJ; Li XM; Ding YQ; Jiao HL; Ye YP
    Cell Mol Life Sci; 2024 Jan; 81(1):57. PubMed ID: 38279052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates.
    Schaefer KN; Peifer M
    Dev Cell; 2019 Feb; 48(4):429-444. PubMed ID: 30782412
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recruitment of adenomatous polyposis coli and beta-catenin to axin-puncta.
    Faux MC; Coates JL; Catimel B; Cody S; Clayton AH; Layton MJ; Burgess AW
    Oncogene; 2008 Oct; 27(44):5808-20. PubMed ID: 18591934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling.
    Wang Z; Tacchelly-Benites O; Yang E; Ahmed Y
    PLoS Genet; 2016 Dec; 12(12):e1006494. PubMed ID: 27959917
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.