141 related articles for article (PubMed ID: 26398935)
1. Impaired APP activity and altered Tau splicing in embryonic stem cell-derived astrocytes obtained from an APPsw transgenic minipig.
Hall VJ; Lindblad MM; Jakobsen JE; Gunnarsson A; Schmidt M; Rasmussen MA; Volke D; Zuchner T; Hyttel P
Dis Model Mech; 2015 Oct; 8(10):1265-78. PubMed ID: 26398935
[TBL] [Abstract][Full Text] [Related]
2. Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
Martiskainen H; Viswanathan J; Nykänen NP; Kurki M; Helisalmi S; Natunen T; Sarajärvi T; Kurkinen KM; Pursiheimo JP; Rauramaa T; Alafuzoff I; Jääskeläinen JE; Leinonen V; Soininen H; Haapasalo A; Huttunen HJ; Hiltunen M
Neurobiol Aging; 2015 Feb; 36(2):1221.e15-28. PubMed ID: 25281018
[TBL] [Abstract][Full Text] [Related]
3. Impact of the cellular prion protein on amyloid-β and 3PO-tau processing.
Schmitz M; Wulf K; Signore SC; Schulz-Schaeffer WJ; Kermer P; Bähr M; Wouters FS; Zafar S; Zerr I
J Alzheimers Dis; 2014; 38(3):551-65. PubMed ID: 24028865
[TBL] [Abstract][Full Text] [Related]
4. Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.
Koch P; Tamboli IY; Mertens J; Wunderlich P; Ladewig J; Stüber K; Esselmann H; Wiltfang J; Brüstle O; Walter J
Am J Pathol; 2012 Jun; 180(6):2404-16. PubMed ID: 22510327
[TBL] [Abstract][Full Text] [Related]
5. Human neural stem cells alleviate Alzheimer-like pathology in a mouse model.
Lee IS; Jung K; Kim IS; Lee H; Kim M; Yun S; Hwang K; Shin JE; Park KI
Mol Neurodegener; 2015 Aug; 10():38. PubMed ID: 26293123
[TBL] [Abstract][Full Text] [Related]
6. Interferon-gamma and tumor necrosis factor-alpha regulate amyloid-beta plaque deposition and beta-secretase expression in Swedish mutant APP transgenic mice.
Yamamoto M; Kiyota T; Horiba M; Buescher JL; Walsh SM; Gendelman HE; Ikezu T
Am J Pathol; 2007 Feb; 170(2):680-92. PubMed ID: 17255335
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological modulation of GSAP reduces amyloid-β levels and tau phosphorylation in a mouse model of Alzheimer's disease with plaques and tangles.
Chu J; Lauretti E; Craige CP; Praticò D
J Alzheimers Dis; 2014; 41(3):729-37. PubMed ID: 24662099
[TBL] [Abstract][Full Text] [Related]
8. Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
España J; Giménez-Llort L; Valero J; Miñano A; Rábano A; Rodriguez-Alvarez J; LaFerla FM; Saura CA
Biol Psychiatry; 2010 Mar; 67(6):513-21. PubMed ID: 19664757
[TBL] [Abstract][Full Text] [Related]
9. Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production.
Suárez-Calvet M; Belbin O; Pera M; Badiola N; Magrané J; Guardia-Laguarta C; Muñoz L; Colom-Cadena M; Clarimón J; Lleó A
J Neurochem; 2014 Jan; 128(2):330-9. PubMed ID: 24117942
[TBL] [Abstract][Full Text] [Related]
10. Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells.
Yang MS; Hong JS; Kim ST; Lee KY; Park KW; Kwon ST; Kweon DH; Koh YH; Gaiano N; Yoon K
Biochem Biophys Res Commun; 2011 Jan; 404(1):133-8. PubMed ID: 21108929
[TBL] [Abstract][Full Text] [Related]
11. Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.
Durairajan SS; Liu LF; Lu JH; Chen LL; Yuan Q; Chung SK; Huang L; Li XS; Huang JD; Li M
Neurobiol Aging; 2012 Dec; 33(12):2903-19. PubMed ID: 22459600
[TBL] [Abstract][Full Text] [Related]
12. Glucocorticoids facilitate astrocytic amyloid-β peptide deposition by increasing the expression of APP and BACE1 and decreasing the expression of amyloid-β-degrading proteases.
Wang Y; Li M; Tang J; Song M; Xu X; Xiong J; Li J; Bai Y
Endocrinology; 2011 Jul; 152(7):2704-15. PubMed ID: 21558319
[TBL] [Abstract][Full Text] [Related]
13. Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw.
Kragh PM; Nielsen AL; Li J; Du Y; Lin L; Schmidt M; Bøgh IB; Holm IE; Jakobsen JE; Johansen MG; Purup S; Bolund L; Vajta G; Jørgensen AL
Transgenic Res; 2009 Aug; 18(4):545-58. PubMed ID: 19184503
[TBL] [Abstract][Full Text] [Related]
14. Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis.
Xu ZQ; Huang H; Chen YL; Gao YY; Xu J; Marshall C; Cai ZY; Xiao M
J Alzheimers Dis; 2016; 51(1):179-95. PubMed ID: 26836155
[TBL] [Abstract][Full Text] [Related]
15. Amyloid-β peptide alteration of tau exon-10 splicing via the GSK3β-SC35 pathway.
Chen KL; Yuan RY; Hu CJ; Hsu CY
Neurobiol Dis; 2010 Nov; 40(2):378-85. PubMed ID: 20615469
[TBL] [Abstract][Full Text] [Related]
16. The blockage of the Nogo/NgR signal pathway in microglia alleviates the formation of Aβ plaques and tau phosphorylation in APP/PS1 transgenic mice.
Fang Y; Yao L; Li C; Wang J; Wang J; Chen S; Zhou XF; Liao H
J Neuroinflammation; 2016 Mar; 13(1):56. PubMed ID: 26939570
[TBL] [Abstract][Full Text] [Related]
17. Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss.
Ager RR; Davis JL; Agazaryan A; Benavente F; Poon WW; LaFerla FM; Blurton-Jones M
Hippocampus; 2015 Jul; 25(7):813-26. PubMed ID: 25530343
[TBL] [Abstract][Full Text] [Related]
18. The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer's disease in vitro and in vivo.
Leirós M; Alonso E; Rateb ME; Ebel R; Jaspars M; Alfonso A; Botana LM
Neuroscience; 2015 Oct; 305():26-35. PubMed ID: 26247694
[TBL] [Abstract][Full Text] [Related]
19. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
20. Astrocytes negatively regulate neurogenesis through the Jagged1-mediated Notch pathway.
Wilhelmsson U; Faiz M; de Pablo Y; Sjöqvist M; Andersson D; Widestrand A; Potokar M; Stenovec M; Smith PL; Shinjyo N; Pekny T; Zorec R; Ståhlberg A; Pekna M; Sahlgren C; Pekny M
Stem Cells; 2012 Oct; 30(10):2320-9. PubMed ID: 22887872
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
