These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 26404503)

  • 1. Cathepsin-Mediated Alterations in TGFß-Related Signaling Underlie Disrupted Cartilage and Bone Maturation Associated With Impaired Lysosomal Targeting.
    Flanagan-Steet H; Aarnio M; Kwan B; Guihard P; Petrey A; Haskins M; Blanchard F; Steet R
    J Bone Miner Res; 2016 Mar; 31(3):535-48. PubMed ID: 26404503
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation.
    Lu PN; Moreland T; Christian CJ; Lund TC; Steet RA; Flanagan-Steet H
    JCI Insight; 2020 Oct; 5(20):. PubMed ID: 33055423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II.
    Petrey AC; Flanagan-Steet H; Johnson S; Fan X; De la Rosa M; Haskins ME; Nairn AV; Moremen KW; Steet R
    Dis Model Mech; 2012 Mar; 5(2):177-90. PubMed ID: 22046029
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development.
    Flanagan-Steet H; Christian C; Lu PN; Aarnio-Peterson M; Sanman L; Archer-Hartmann S; Azadi P; Bogyo M; Steet RA
    Cell Rep; 2018 Mar; 22(11):2964-2977. PubMed ID: 29539424
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Altered chondrocyte differentiation and extracellular matrix homeostasis in a zebrafish model for mucolipidosis II.
    Flanagan-Steet H; Sias C; Steet R
    Am J Pathol; 2009 Nov; 175(5):2063-75. PubMed ID: 19834066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II.
    Kollmann K; Pestka JM; Kühn SC; Schöne E; Schweizer M; Karkmann K; Otomo T; Catala-Lehnen P; Failla AV; Marshall RP; Krause M; Santer R; Amling M; Braulke T; Schinke T
    EMBO Mol Med; 2013 Dec; 5(12):1871-86. PubMed ID: 24127423
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mannose 6-phosphate-dependent targeting of lysosomal enzymes is required for normal craniofacial and dental development.
    Koehne T; Markmann S; Schweizer M; Muschol N; Friedrich RE; Hagel C; Glatzel M; Kahl-Nieke B; Amling M; Schinke T; Braulke T
    Biochim Biophys Acta; 2016 Sep; 1862(9):1570-80. PubMed ID: 27239697
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Upregulation of Sortilin, a Lysosomal Sorting Receptor, Corresponds with Reduced Bioavailability of Latent TGFβ in Mucolipidosis II Cells.
    Barnes JW; Aarnio-Peterson M; Norris J; Haskins M; Flanagan-Steet H; Steet R
    Biomolecules; 2020 Apr; 10(5):. PubMed ID: 32357547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bone morphogenetic proteins in bone stimulate osteoclasts and osteoblasts during bone development.
    Okamoto M; Murai J; Yoshikawa H; Tsumaki N
    J Bone Miner Res; 2006 Jul; 21(7):1022-33. PubMed ID: 16813523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development.
    Zhang D; Schwarz EM; Rosier RN; Zuscik MJ; Puzas JE; O'Keefe RJ
    J Bone Miner Res; 2003 Sep; 18(9):1593-604. PubMed ID: 12968668
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Excess BMP Signaling in Heterotopic Cartilage Forming in Prg4-null TMJ Discs.
    Bechtold TE; Saunders C; Mundy C; Um H; Decker RS; Salhab I; Kurio N; Billings PC; Pacifici M; Nah HD; Koyama E
    J Dent Res; 2016 Mar; 95(3):292-301. PubMed ID: 26534931
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Paracrine and autocrine signals promoting full chondrogenic differentiation of a mesoblastic cell line.
    Locker M; Kellermann O; Boucquey M; Khun H; Huerre M; Poliard A
    J Bone Miner Res; 2004 Jan; 19(1):100-10. PubMed ID: 14753742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma.
    Westermann LM; Fleischhauer L; Vogel J; Jenei-Lanzl Z; Ludwig NF; Schau L; Morellini F; Baranowsky A; Yorgan TA; Di Lorenzo G; Schweizer M; de Souza Pinheiro B; Guarany NR; Sperb-Ludwig F; Visioli F; Oliveira Silva T; Soul J; Hendrickx G; Wiegert JS; Schwartz IVD; Clausen-Schaumann H; Zaucke F; Schinke T; Pohl S; Danyukova T
    Dis Model Mech; 2020 Nov; 13(11):. PubMed ID: 33023972
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.
    Zuscik MJ; Baden JF; Wu Q; Sheu TJ; Schwarz EM; Drissi H; O'Keefe RJ; Puzas JE; Rosier RN
    J Cell Biochem; 2004 May; 92(2):316-31. PubMed ID: 15108358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.
    Horiki M; Imamura T; Okamoto M; Hayashi M; Murai J; Myoui A; Ochi T; Miyazono K; Yoshikawa H; Tsumaki N
    J Cell Biol; 2004 May; 165(3):433-45. PubMed ID: 15123739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Heparan sulfate proteoglycans including syndecan-3 modulate BMP activity during limb cartilage differentiation.
    Fisher MC; Li Y; Seghatoleslami MR; Dealy CN; Kosher RA
    Matrix Biol; 2006 Jan; 25(1):27-39. PubMed ID: 16226436
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced hyaline cartilage matrix synthesis in collagen sponge scaffolds by using siRNA to stabilize chondrocytes phenotype cultured with bone morphogenetic protein-2 under hypoxia.
    Legendre F; Ollitrault D; Hervieu M; Baugé C; Maneix L; Goux D; Chajra H; Mallein-Gerin F; Boumediene K; Galera P; Demoor M
    Tissue Eng Part C Methods; 2013 Jul; 19(7):550-67. PubMed ID: 23270543
    [TBL] [Abstract][Full Text] [Related]  

  • 18. EFTUD2 gene deficiency disrupts osteoblast maturation and inhibits chondrocyte differentiation via activation of the p53 signaling pathway.
    Wu J; Yang Y; He Y; Li Q; Wang X; Sun C; Wang L; An Y; Luo F
    Hum Genomics; 2019 Dec; 13(1):63. PubMed ID: 31806011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.
    Li TF; Darowish M; Zuscik MJ; Chen D; Schwarz EM; Rosier RN; Drissi H; O'Keefe RJ
    J Bone Miner Res; 2006 Jan; 21(1):4-16. PubMed ID: 16355269
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Distinct Modes of Balancing Glomerular Cell Proteostasis in Mucolipidosis Type II and III Prevent Proteinuria.
    Sachs W; Sachs M; Krüger E; Zielinski S; Kretz O; Huber TB; Baranowsky A; Westermann LM; Voltolini Velho R; Ludwig NF; Yorgan TA; Di Lorenzo G; Kollmann K; Braulke T; Schwartz IV; Schinke T; Danyukova T; Pohl S; Meyer-Schwesinger C
    J Am Soc Nephrol; 2020 Aug; 31(8):1796-1814. PubMed ID: 32641396
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.