119 related articles for article (PubMed ID: 26408686)
1. The New Semisynthetic Cardenolide Analog 3β-[2-(1-Amantadine)-1-on-ethylamine]-digitoxigenin (AMANTADIG) Efficiently Suppresses Cell Growth in Human Leukemia and Urological Tumor Cell Lines.
Nolte E; Sobel A; Wach S; Hertlein H; Ebert N; Müller-Uri F; Slany R; Taubert H; Wullich B; Kreis W
Anticancer Res; 2015 Oct; 35(10):5271-5. PubMed ID: 26408686
[TBL] [Abstract][Full Text] [Related]
2. A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines.
Nolte E; Wach S; Silva IT; Lukat S; Ekici AB; Munkert J; Müller-Uri F; Kreis W; Oliveira Simões CM; Vera J; Wullich B; Taubert H; Lai X
Oncotarget; 2017 Feb; 8(7):11676-11691. PubMed ID: 28099931
[TBL] [Abstract][Full Text] [Related]
3. Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na
Silva IT; Munkert J; Nolte E; Schneider NFZ; Rocha SC; Ramos ACP; Kreis W; Braga FC; de Pádua RM; Taranto AG; Cortes V; Barbosa LA; Wach S; Taubert H; Simões CMO
Biomed Pharmacother; 2018 Nov; 107():464-474. PubMed ID: 30107342
[TBL] [Abstract][Full Text] [Related]
4. C3'/C4'-Stereochemical Effects of Digitoxigenin α-L-/α-D-Glycoside in Cancer Cytotoxicity.
Hinds JW; McKenna SB; Sharif EU; Wang HY; Akhmedov NG; O'Doherty GA
ChemMedChem; 2013 Jan; 8(1):63-9. PubMed ID: 23139074
[TBL] [Abstract][Full Text] [Related]
5. Cytotoxic and cytostatic effects of digitoxigenin monodigitoxoside (DGX) in human lung cancer cells and its link to Na,K-ATPase.
Schneider NFZ; Persich L; Rocha SC; Ramos ACP; Cortes VF; Silva IT; Munkert J; Pádua RM; Kreis W; Taranto AG; Barbosa LA; Braga FC; Simões CMO
Biomed Pharmacother; 2018 Jan; 97():684-696. PubMed ID: 29101813
[TBL] [Abstract][Full Text] [Related]
6. Potential anti-herpes and cytotoxic action of novel semisynthetic digitoxigenin-derivatives.
Boff L; Munkert J; Ottoni FM; Zanchett Schneider NF; Ramos GS; Kreis W; Fernandes de Andrade S; Dias de Souza Filho J; Braga FC; Alves RJ; Maia de Pádua R; Oliveira Simões CM
Eur J Med Chem; 2019 Apr; 167():546-561. PubMed ID: 30798081
[TBL] [Abstract][Full Text] [Related]
7. [Synthesis and characterization of some cardenolide glucuronides and sulphates (author's transl)].
Petersen R; Flasch H; Heinz N
Arzneimittelforschung; 1977; 27(3):642-9. PubMed ID: 577437
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of cell proliferation, invasion and migration by the cardenolides digitoxigenin monodigitoxoside and convallatoxin in human lung cancer cell line.
Schneider NF; Geller FC; Persich L; Marostica LL; Pádua RM; Kreis W; Braga FC; Simões CM
Nat Prod Res; 2016 Jun; 30(11):1327-31. PubMed ID: 26252521
[TBL] [Abstract][Full Text] [Related]
9. Comparison of digitoxin and its major glucuronidated metabolite: inhibition of Na-K-ATPase and reactivity with the radioimmunoassay.
Castle MC; Zavecz JH
Res Commun Chem Pathol Pharmacol; 1987 Apr; 56(1):33-48. PubMed ID: 3035659
[TBL] [Abstract][Full Text] [Related]
10. Cardenolide aglycones inhibit tumor necrosis factor α-induced expression of intercellular adhesion molecule-1 at the translation step by blocking Na⁺/K⁺-ATPase.
Okina Y; Takeuchi F; Yokomichi T; Takada Y; Kataoka T
Biol Pharm Bull; 2015; 38(1):39-47. PubMed ID: 25744456
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological investigation on asclepin--a new cardenolide from Asclepias curassavica. Part II. Comparative studies on the inotropic and toxic effects of asclepin, g-strophantin, digoxin and digitoxin).
Patnaik GK; Köhler E
Arzneimittelforschung; 1978; 28(8):1368-72. PubMed ID: 380581
[TBL] [Abstract][Full Text] [Related]
12. The effects of digitoxin and its metabolites on the transmembrane potential and contractile characteristics of guinea-pig ventricle strips.
Stephen PM; Marks BH; Hollander PB
Arch Int Pharmacodyn Ther; 1976 Nov; 224(1):43-54. PubMed ID: 1015913
[TBL] [Abstract][Full Text] [Related]
13. Potential antitumor activity of digitoxin and user-designed analog administered to human lung cancer cells.
Eldawud R; Wagner A; Dong C; Gupta N; Rojanasakul Y; O'Doherty G; Stueckle TA; Dinu CZ
Biochim Biophys Acta Gen Subj; 2020 Nov; 1864(11):129683. PubMed ID: 32679249
[TBL] [Abstract][Full Text] [Related]
14. Investigation of the cytotoxic activity of two novel digitoxigenin analogues on H460 lung cancer cells.
Boff L; Persich L; Brambila P; Ottoni FM; Munkert J; Ramos GS; Soares Viana AR; Kreis W; Braga FC; Alves RJ; Maia de Pádua R; Schneider NFZ; Oliveira Simões CM
Anticancer Drugs; 2020 Jun; 31(5):452-462. PubMed ID: 32079825
[TBL] [Abstract][Full Text] [Related]
15. Structures, chemotaxonomic significance, cytotoxic and Na(+),K(+)-ATPase inhibitory activities of new cardenolides from Asclepias curassavica.
Zhang RR; Tian HY; Tan YF; Chung TY; Sun XH; Xia X; Ye WC; Middleton DA; Fedosova N; Esmann M; Tzen JT; Jiang RW
Org Biomol Chem; 2014 Nov; 12(44):8919-29. PubMed ID: 25270760
[TBL] [Abstract][Full Text] [Related]
16. Production of the Cytotoxic Cardenolide Glucoevatromonoside by Semisynthesis and Biotransformation of Evatromonoside by a Digitalis lanata Cell Culture.
Munkert J; Santiago Franco M; Nolte E; Thaís Silva I; Oliveira Castilho R; Melo Ottoni F; Schneider NFZ; Oliveira MC; Taubert H; Bauer W; Andrade SF; Alves RJ; Simões CMO; Braga FC; Kreis W; de Pádua RM
Planta Med; 2017 Aug; 83(12-13):1035-1043. PubMed ID: 28486743
[TBL] [Abstract][Full Text] [Related]
17. Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells.
Einbond LS; Shimizu M; Ma H; Wu HA; Goldsberry S; Sicular S; Panjikaran M; Genovese G; Cruz E
Biochem Biophys Res Commun; 2008 Oct; 375(4):608-13. PubMed ID: 18755149
[TBL] [Abstract][Full Text] [Related]
18. Cardenolide glycosides from root of Streptocaulon juventas.
Xue R; Han N; Ye C; Wang HB; Yin J
Phytochemistry; 2013 Apr; 88():105-11. PubMed ID: 23286880
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs.
Jensen M; Schmidt S; Fedosova NU; Mollenhauer J; Jensen HH
Bioorg Med Chem; 2011 Apr; 19(7):2407-17. PubMed ID: 21421322
[TBL] [Abstract][Full Text] [Related]
20. Cytotoxicity of digitoxin and related cardiac glycosides in human tumor cells.
Johansson S; Lindholm P; Gullbo J; Larsson R; Bohlin L; Claeson P
Anticancer Drugs; 2001 Jun; 12(5):475-83. PubMed ID: 11395576
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
