BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

931 related articles for article (PubMed ID: 26413872)

  • 1. TIGIT predominantly regulates the immune response via regulatory T cells.
    Kurtulus S; Sakuishi K; Ngiow SF; Joller N; Tan DJ; Teng MW; Smyth MJ; Kuchroo VK; Anderson AC
    J Clin Invest; 2015 Nov; 125(11):4053-62. PubMed ID: 26413872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients.
    Chauvin JM; Pagliano O; Fourcade J; Sun Z; Wang H; Sander C; Kirkwood JM; Chen TH; Maurer M; Korman AJ; Zarour HM
    J Clin Invest; 2015 May; 125(5):2046-58. PubMed ID: 25866972
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226.
    Fuhrman CA; Yeh WI; Seay HR; Saikumar Lakshmi P; Chopra G; Zhang L; Perry DJ; McClymont SA; Yadav M; Lopez MC; Baker HV; Zhang Y; Li Y; Whitley M; von Schack D; Atkinson MA; Bluestone JA; Brusko TM
    J Immunol; 2015 Jul; 195(1):145-55. PubMed ID: 25994968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Blockade of TIGIT/CD155 Signaling Reverses T-cell Exhaustion and Enhances Antitumor Capability in Head and Neck Squamous Cell Carcinoma.
    Wu L; Mao L; Liu JF; Chen L; Yu GT; Yang LL; Wu H; Bu LL; Kulkarni AB; Zhang WF; Sun ZJ
    Cancer Immunol Res; 2019 Oct; 7(10):1700-1713. PubMed ID: 31387897
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Restoration of T-cell Effector Function, Depletion of Tregs, and Direct Killing of Tumor Cells: The Multiple Mechanisms of Action of a-TIGIT Antagonist Antibodies.
    Preillon J; Cuende J; Rabolli V; Garnero L; Mercier M; Wald N; Pappalardo A; Denies S; Jamart D; Michaux AC; Pirson R; Pitard V; Bagot M; Prasad S; Houthuys E; Brouwer M; Marillier R; Lambolez F; Marchante JR; Nyawouame F; Carter MJ; Baron-Bodo V; Marie-Cardine A; Cragg M; Déchanet-Merville J; Driessens G; Hoofd C
    Mol Cancer Ther; 2021 Jan; 20(1):121-131. PubMed ID: 33277440
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models.
    Leone RD; Sun IM; Oh MH; Sun IH; Wen J; Englert J; Powell JD
    Cancer Immunol Immunother; 2018 Aug; 67(8):1271-1284. PubMed ID: 29923026
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The immunoreceptor TIGIT regulates antitumor and antiviral CD8(+) T cell effector function.
    Johnston RJ; Comps-Agrar L; Hackney J; Yu X; Huseni M; Yang Y; Park S; Javinal V; Chiu H; Irving B; Eaton DL; Grogan JL
    Cancer Cell; 2014 Dec; 26(6):923-937. PubMed ID: 25465800
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TX99 Is a Neutralizing Monoclonal Antibody Against Mouse TIGIT.
    Nakamura Y; Naito K; Yamashita-Kanemaru Y; Komori D; Hirochika R; Shibuya A; Shibuya K
    Monoclon Antib Immunodiagn Immunother; 2018 Apr; 37(2):105-109. PubMed ID: 29648914
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatocellular Carcinoma Cells Up-regulate PVRL1, Stabilizing PVR and Inhibiting the Cytotoxic T-Cell Response via TIGIT to Mediate Tumor Resistance to PD1 Inhibitors in Mice.
    Chiu DK; Yuen VW; Cheu JW; Wei LL; Ting V; Fehlings M; Sumatoh H; Nardin A; Newell EW; Ng IO; Yau TC; Wong CM; Wong CC
    Gastroenterology; 2020 Aug; 159(2):609-623. PubMed ID: 32275969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Melanoma Cells Control Antimelanoma CTL Responses via Interaction between TIGIT and CD155 in the Effector Phase.
    Inozume T; Yaguchi T; Furuta J; Harada K; Kawakami Y; Shimada S
    J Invest Dermatol; 2016 Jan; 136(1):255-63. PubMed ID: 26763445
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CD226 opposes TIGIT to disrupt Tregs in melanoma.
    Fourcade J; Sun Z; Chauvin JM; Ka M; Davar D; Pagliano O; Wang H; Saada S; Menna C; Amin R; Sander C; Kirkwood JM; Korman AJ; Zarour HM
    JCI Insight; 2018 Jul; 3(14):. PubMed ID: 30046006
    [TBL] [Abstract][Full Text] [Related]  

  • 12. T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling.
    Josefsson SE; Huse K; Kolstad A; Beiske K; Pende D; Steen CB; Inderberg EM; Lingjærde OC; Østenstad B; Smeland EB; Levy R; Irish JM; Myklebust JH
    Clin Cancer Res; 2018 Feb; 24(4):870-881. PubMed ID: 29217528
    [No Abstract]   [Full Text] [Related]  

  • 13. TIGIT, A Novel Therapeutic Target for Tumor Immunotherapy.
    Liu XG; Hou M; Liu Y
    Immunol Invest; 2017 Feb; 46(2):172-182. PubMed ID: 27819527
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD155T/TIGIT Signaling Regulates CD8
    He W; Zhang H; Han F; Chen X; Lin R; Wang W; Qiu H; Zhuang Z; Liao Q; Zhang W; Cai Q; Cui Y; Jiang W; Wang H; Ke Z
    Cancer Res; 2017 Nov; 77(22):6375-6388. PubMed ID: 28883004
    [TBL] [Abstract][Full Text] [Related]  

  • 15. T-cell Ig and ITIM domain regulates natural killer cell activation in murine acute viral hepatitis.
    Bi J; Zhang Q; Liang D; Xiong L; Wei H; Sun R; Tian Z
    Hepatology; 2014 May; 59(5):1715-25. PubMed ID: 24319005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.
    Zhang Q; Bi J; Zheng X; Chen Y; Wang H; Wu W; Wang Z; Wu Q; Peng H; Wei H; Sun R; Tian Z
    Nat Immunol; 2018 Jul; 19(7):723-732. PubMed ID: 29915296
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Instability of Helios-deficient Tregs is associated with conversion to a T-effector phenotype and enhanced antitumor immunity.
    Nakagawa H; Sido JM; Reyes EE; Kiers V; Cantor H; Kim HJ
    Proc Natl Acad Sci U S A; 2016 May; 113(22):6248-53. PubMed ID: 27185917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNAM-1 regulates Foxp3 expression in regulatory T cells by interfering with TIGIT under inflammatory conditions.
    Sato K; Yamashita-Kanemaru Y; Abe F; Murata R; Nakamura-Shinya Y; Kanemaru K; Muratani M; Veillette A; Goto M; Ito M; Shibuya A; Shibuya K
    Proc Natl Acad Sci U S A; 2021 May; 118(21):. PubMed ID: 34011606
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TIGIT safeguards liver regeneration through regulating natural killer cell-hepatocyte crosstalk.
    Bi J; Zheng X; Chen Y; Wei H; Sun R; Tian Z
    Hepatology; 2014 Oct; 60(4):1389-98. PubMed ID: 24912841
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1.
    Ngiow SF; Young A; Jacquelot N; Yamazaki T; Enot D; Zitvogel L; Smyth MJ
    Cancer Res; 2015 Sep; 75(18):3800-11. PubMed ID: 26208901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.