BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

552 related articles for article (PubMed ID: 26414661)

  • 1. High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.
    Maesako M; Uemura M; Tashiro Y; Sasaki K; Watanabe K; Noda Y; Ueda K; Asada-Utsugi M; Kubota M; Okawa K; Ihara M; Shimohama S; Uemura K; Kinoshita A
    PLoS One; 2015; 10(9):e0131199. PubMed ID: 26414661
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
    Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
    Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.
    Prabhu Y; Burgos PV; Schindler C; Farías GG; Magadán JG; Bonifacino JS
    Mol Biol Cell; 2012 Jun; 23(12):2339-51. PubMed ID: 22553349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation.
    Lakshmana MK; Yoon IS; Chen E; Bianchi E; Koo EH; Kang DE
    J Biol Chem; 2009 May; 284(18):11863-72. PubMed ID: 19251705
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
    Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
    J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autophagy-mediated Regulation of BACE1 Protein Trafficking and Degradation.
    Feng T; Tammineni P; Agrawal C; Jeong YY; Cai Q
    J Biol Chem; 2017 Feb; 292(5):1679-1690. PubMed ID: 28028177
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of low-density receptor-related protein 1 (LRP1) as a competitive substrate of the amyloid precursor protein (APP) for BACE1.
    von Einem B; Schwanzar D; Rehn F; Beyer AS; Weber P; Wagner M; Schneckenburger H; von Arnim CA
    Exp Neurol; 2010 Sep; 225(1):85-93. PubMed ID: 20685197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
    Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
    J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
    Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
    Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Β-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis.
    Tan J; Evin G
    J Neurochem; 2012 Mar; 120(6):869-80. PubMed ID: 22171895
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disrupted-in-Schizophrenia-1 Attenuates Amyloid-β Generation and Cognitive Deficits in APP/PS1 Transgenic Mice by Reduction of β-Site APP-Cleaving Enzyme 1 Levels.
    Deng QS; Dong XY; Wu H; Wang W; Wang ZT; Zhu JW; Liu CF; Jia WQ; Zhang Y; Schachner M; Ma QH; Xu RX
    Neuropsychopharmacology; 2016 Jan; 41(2):440-53. PubMed ID: 26062786
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
    Devi L; Ohno M
    Neuroscience; 2015 Oct; 307():128-37. PubMed ID: 26314636
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The circular RNA ciRS-7 promotes APP and BACE1 degradation in an NF-κB-dependent manner.
    Shi Z; Chen T; Yao Q; Zheng L; Zhang Z; Wang J; Hu Z; Cui H; Han Y; Han X; Zhang K; Hong W
    FEBS J; 2017 Apr; 284(7):1096-1109. PubMed ID: 28296235
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model.
    Shi Z; Hong Y; Zhang K; Wang J; Zheng L; Zhang Z; Hu Z; Han X; Han Y; Chen T; Yao Q; Cui H; Hong W
    Biochim Biophys Acta Mol Basis Dis; 2017 Sep; 1863(9):2398-2407. PubMed ID: 28502705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
    von Einem B; Wahler A; Schips T; Serrano-Pozo A; Proepper C; Boeckers TM; Rueck A; Wirth T; Hyman BT; Danzer KM; Thal DR; von Arnim CA
    PLoS One; 2015; 10(6):e0129047. PubMed ID: 26053850
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.