These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
8. Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. Qi G; Chatterjee N PLoS Genet; 2018 Oct; 14(10):e1007549. PubMed ID: 30289880 [TBL] [Abstract][Full Text] [Related]
9. Disease Heritability Enrichment of Regulatory Elements Is Concentrated in Elements with Ancient Sequence Age and Conserved Function across Species. Hujoel MLA; Gazal S; Hormozdiari F; van de Geijn B; Price AL Am J Hum Genet; 2019 Apr; 104(4):611-624. PubMed ID: 30905396 [TBL] [Abstract][Full Text] [Related]
10. Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data. Shi J; Park JH; Duan J; Berndt ST; Moy W; Yu K; Song L; Wheeler W; Hua X; Silverman D; Garcia-Closas M; Hsiung CA; Figueroa JD; Cortessis VK; Malats N; Karagas MR; Vineis P; Chang IS; Lin D; Zhou B; Seow A; Matsuo K; Hong YC; Caporaso NE; Wolpin B; Jacobs E; Petersen GM; Klein AP; Li D; Risch H; Sanders AR; Hsu L; Schoen RE; Brenner H; ; ; ; ; ; ; Stolzenberg-Solomon R; Gejman P; Lan Q; Rothman N; Amundadottir LT; Landi MT; Levinson DF; Chanock SJ; Chatterjee N PLoS Genet; 2016 Dec; 12(12):e1006493. PubMed ID: 28036406 [TBL] [Abstract][Full Text] [Related]
11. Evaluating and improving heritability models using summary statistics. Speed D; Holmes J; Balding DJ Nat Genet; 2020 Apr; 52(4):458-462. PubMed ID: 32203469 [TBL] [Abstract][Full Text] [Related]
12. Hints of hidden heritability in GWAS. Gibson G Nat Genet; 2010 Jul; 42(7):558-60. PubMed ID: 20581876 [TBL] [Abstract][Full Text] [Related]
13. Estimating the total number of susceptibility variants underlying complex diseases from genome-wide association studies. So HC; Yip BH; Sham PC PLoS One; 2010 Nov; 5(11):e13898. PubMed ID: 21103334 [TBL] [Abstract][Full Text] [Related]
14. Reevaluation of SNP heritability in complex human traits. Speed D; Cai N; ; Johnson MR; Nejentsev S; Balding DJ Nat Genet; 2017 Jul; 49(7):986-992. PubMed ID: 28530675 [TBL] [Abstract][Full Text] [Related]
15. Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data. Shi H; Kichaev G; Pasaniuc B Am J Hum Genet; 2016 Jul; 99(1):139-53. PubMed ID: 27346688 [TBL] [Abstract][Full Text] [Related]
16. Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. Chen GB; Lee SH; Brion MJ; Montgomery GW; Wray NR; Radford-Smith GL; Visscher PM; Hum Mol Genet; 2014 Sep; 23(17):4710-20. PubMed ID: 24728037 [TBL] [Abstract][Full Text] [Related]
17. Assumptions about frequency-dependent architectures of complex traits bias measures of functional enrichment. Zabad S; Ragsdale AP; Sun R; Li Y; Gravel S Genet Epidemiol; 2021 Sep; 45(6):621-632. PubMed ID: 34157784 [TBL] [Abstract][Full Text] [Related]
18. Estimation of complex effect-size distributions using summary-level statistics from genome-wide association studies across 32 complex traits. Zhang Y; Qi G; Park JH; Chatterjee N Nat Genet; 2018 Sep; 50(9):1318-1326. PubMed ID: 30104760 [TBL] [Abstract][Full Text] [Related]