These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
44. Mechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand. Ahn B; Lee JW; Jung H; Beck G; Bohr VA PLoS One; 2009; 4(3):e4673. PubMed ID: 19262689 [TBL] [Abstract][Full Text] [Related]
45. Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein. von Kobbe C; Harrigan JA; Schreiber V; Stiegler P; Piotrowski J; Dawut L; Bohr VA Nucleic Acids Res; 2004; 32(13):4003-14. PubMed ID: 15292449 [TBL] [Abstract][Full Text] [Related]
46. Residues in the RecQ C-terminal Domain of the Human Werner Syndrome Helicase Are Involved in Unwinding G-quadruplex DNA. Ketkar A; Voehler M; Mukiza T; Eoff RL J Biol Chem; 2017 Feb; 292(8):3154-3163. PubMed ID: 28069813 [TBL] [Abstract][Full Text] [Related]
47. Werner syndrome helicase contains a 5'-->3' exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding. Suzuki N; Shiratori M; Goto M; Furuichi Y Nucleic Acids Res; 1999 Jun; 27(11):2361-8. PubMed ID: 10325426 [TBL] [Abstract][Full Text] [Related]
48. Targeted inhibition of WRN helicase by external guide sequence and RNase P RNA. Hitrik A; Abboud-Jarrous G; Orlovetskie N; Serruya R; Jarrous N Biochim Biophys Acta; 2016 Apr; 1859(4):572-80. PubMed ID: 26808708 [TBL] [Abstract][Full Text] [Related]
49. Multimerization domains are associated with apparent strand exchange activity in BLM and WRN DNA helicases. Chen CF; Brill SJ DNA Repair (Amst); 2014 Oct; 22():137-46. PubMed ID: 25198671 [TBL] [Abstract][Full Text] [Related]
50. The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease. Huang S; Li B; Gray MD; Oshima J; Mian IS; Campisi J Nat Genet; 1998 Oct; 20(2):114-6. PubMed ID: 9771700 [No Abstract] [Full Text] [Related]
51. The Werner syndrome protein: an update. Oshima J Bioessays; 2000 Oct; 22(10):894-901. PubMed ID: 10984715 [TBL] [Abstract][Full Text] [Related]
52. Depletion of Werner helicase results in mitotic hyperrecombination and pleiotropic homologous and nonhomologous recombination phenotypes. Rahn JJ; Lowery MP; Della-Coletta L; Adair GM; Nairn RS Mech Ageing Dev; 2010 Sep; 131(9):562-73. PubMed ID: 20708636 [TBL] [Abstract][Full Text] [Related]
53. Deficient DNA repair in the human progeroid disorder, Werner syndrome. Bohr VA Mutat Res; 2005 Sep; 577(1-2):252-9. PubMed ID: 15916783 [TBL] [Abstract][Full Text] [Related]
54. Premature aging syndrome gene WRN genetically interacts with a topoisomerase. Aggarwal M; Brosh RM Cell Cycle; 2009 Jul; 8(14):2143. PubMed ID: 19587535 [No Abstract] [Full Text] [Related]
55. WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts. Zecevic A; Menard H; Gurel V; Hagan E; DeCaro R; Zhitkovich A Cell Cycle; 2009 Sep; 8(17):2769-78. PubMed ID: 19652551 [TBL] [Abstract][Full Text] [Related]
56. CDK2 phosphorylation of Werner protein (WRN) contributes to WRN's DNA double-strand break repair pathway choice. Lee JH; Shamanna RA; Kulikowicz T; Borhan Fakouri N; Kim EW; Christiansen LS; Croteau DL; Bohr VA Aging Cell; 2021 Nov; 20(11):e13484. PubMed ID: 34612580 [TBL] [Abstract][Full Text] [Related]
57. Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway. Laud PR; Multani AS; Bailey SM; Wu L; Ma J; Kingsley C; Lebel M; Pathak S; DePinho RA; Chang S Genes Dev; 2005 Nov; 19(21):2560-70. PubMed ID: 16264192 [TBL] [Abstract][Full Text] [Related]
58. Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors. Saydam N; Kanagaraj R; Dietschy T; Garcia PL; Peña-Diaz J; Shevelev I; Stagljar I; Janscak P Nucleic Acids Res; 2007; 35(17):5706-16. PubMed ID: 17715146 [TBL] [Abstract][Full Text] [Related]
59. Quantitative analysis of Werner helicase activity using the single-molecule fluorescence detection system MF10S. Futami K; Goto H; Shimamoto A; Watanabe T; Furuichi Y Biol Pharm Bull; 2005 Jan; 28(1):9-12. PubMed ID: 15635154 [TBL] [Abstract][Full Text] [Related]
60. Acetylation of Werner syndrome protein (WRN): relationships with DNA damage, DNA replication and DNA metabolic activities. Lozada E; Yi J; Luo J; Orren DK Biogerontology; 2014 Aug; 15(4):347-66. PubMed ID: 24965941 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]