316 related articles for article (PubMed ID: 26420482)
1. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor.
Zhang H; Unal H; Desnoyer R; Han GW; Patel N; Katritch V; Karnik SS; Cherezov V; Stevens RC
J Biol Chem; 2015 Dec; 290(49):29127-39. PubMed ID: 26420482
[TBL] [Abstract][Full Text] [Related]
2. Divergent Spatiotemporal Interaction of Angiotensin Receptor Blocking Drugs with Angiotensin Type 1 Receptor.
Singh KD; Unal H; Desnoyer R; Karnik SS
J Chem Inf Model; 2018 Jan; 58(1):182-193. PubMed ID: 29195045
[TBL] [Abstract][Full Text] [Related]
3. Structure-Function Basis of Attenuated Inverse Agonism of Angiotensin II Type 1 Receptor Blockers for Active-State Angiotensin II Type 1 Receptor.
Takezako T; Unal H; Karnik SS; Node K
Mol Pharmacol; 2015 Sep; 88(3):488-501. PubMed ID: 26121982
[TBL] [Abstract][Full Text] [Related]
4. Angiotensin II Type 1 Receptor Homology Models: A Comparison Between In Silico and the Crystal Structures.
Kellici TF
Methods Mol Biol; 2018; 1824():449-460. PubMed ID: 30039424
[TBL] [Abstract][Full Text] [Related]
5. Differential bonding interactions of inverse agonists of angiotensin II type 1 receptor in stabilizing the inactive state.
Miura S; Kiya Y; Kanazawa T; Imaizumi S; Fujino M; Matsuo Y; Karnik SS; Saku K
Mol Endocrinol; 2008 Jan; 22(1):139-46. PubMed ID: 17901125
[TBL] [Abstract][Full Text] [Related]
6. Current topics in angiotensin II type 1 receptor research: Focus on inverse agonism, receptor dimerization and biased agonism.
Takezako T; Unal H; Karnik SS; Node K
Pharmacol Res; 2017 Sep; 123():40-50. PubMed ID: 28648738
[TBL] [Abstract][Full Text] [Related]
7. Molecular mechanism underlying inverse agonist of angiotensin II type 1 receptor.
Miura S; Fujino M; Hanzawa H; Kiya Y; Imaizumi S; Matsuo Y; Tomita S; Uehara Y; Karnik SS; Yanagisawa H; Koike H; Komuro I; Saku K
J Biol Chem; 2006 Jul; 281(28):19288-95. PubMed ID: 16690611
[TBL] [Abstract][Full Text] [Related]
8. Immobilized angiotensin II type I receptor: A powerful method of high throughput screening for antihypertensive compound identification through binding interaction analysis.
Liang Q; Fu X; Zhang J; Hao J; Feng G; Wang J; Li Q; Ahmad F; Zhao X
J Chromatogr A; 2020 Jun; 1620():461003. PubMed ID: 32156458
[TBL] [Abstract][Full Text] [Related]
9. In silico prediction of ARB resistance: A first step in creating personalized ARB therapy.
Anderson SD; Tabassum A; Yeon JK; Sharma G; Santos P; Soong TH; Thu YW; Nies I; Kurita T; Chandler A; Alsamarah A; Kanassatega RS; Luo YL; Botello-Smith WM; Andresen BT
PLoS Comput Biol; 2020 Nov; 16(11):e1007719. PubMed ID: 33237899
[TBL] [Abstract][Full Text] [Related]
10. Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor.
Unal H; Jagannathan R; Bhatnagar A; Tirupula K; Desnoyer R; Karnik SS
J Biol Chem; 2013 Jan; 288(1):540-51. PubMed ID: 23139413
[TBL] [Abstract][Full Text] [Related]
11. Ligand-specific conformation of extracellular loop-2 in the angiotensin II type 1 receptor.
Unal H; Jagannathan R; Bhat MB; Karnik SS
J Biol Chem; 2010 May; 285(21):16341-50. PubMed ID: 20299456
[TBL] [Abstract][Full Text] [Related]
12. Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.
Zhang H; Unal H; Gati C; Han GW; Liu W; Zatsepin NA; James D; Wang D; Nelson G; Weierstall U; Sawaya MR; Xu Q; Messerschmidt M; Williams GJ; Boutet S; Yefanov OM; White TA; Wang C; Ishchenko A; Tirupula KC; Desnoyer R; Coe J; Conrad CE; Fromme P; Stevens RC; Katritch V; Karnik SS; Cherezov V
Cell; 2015 May; 161(4):833-44. PubMed ID: 25913193
[TBL] [Abstract][Full Text] [Related]
13. Multivalent ligand-receptor interactions elicit inverse agonist activity of AT(1) receptor blockers against stretch-induced AT(1) receptor activation.
Qin Y; Yasuda N; Akazawa H; Ito K; Kudo Y; Liao CH; Yamamoto R; Miura S; Saku K; Komuro I
Hypertens Res; 2009 Oct; 32(10):875-83. PubMed ID: 19662020
[TBL] [Abstract][Full Text] [Related]
14. Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode.
Fillion D; Cabana J; Guillemette G; Leduc R; Lavigne P; Escher E
J Biol Chem; 2013 Mar; 288(12):8187-8197. PubMed ID: 23386604
[TBL] [Abstract][Full Text] [Related]
15. β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats.
Del Borgo M; Wang Y; Bosnyak S; Khan M; Walters P; Spizzo I; Perlmutter P; Hilliard L; Denton K; Aguilar MI; Widdop RE; Jones ES
Clin Sci (Lond); 2015 Sep; 129(6):505-13. PubMed ID: 26186568
[TBL] [Abstract][Full Text] [Related]
16. Biased Agonist TRV027 Determinants in AT1R by Molecular Dynamics Simulations.
Modestia SM; Malta de Sá M; Auger E; Trossini GHG; Krieger JE; Rangel-Yagui CO
J Chem Inf Model; 2019 Feb; 59(2):797-808. PubMed ID: 30668103
[TBL] [Abstract][Full Text] [Related]
17. Angiotensin type 1A receptor regulates β-arrestin binding of the β
Tóth AD; Gyombolai P; Szalai B; Várnai P; Turu G; Hunyady L
Mol Cell Endocrinol; 2017 Feb; 442():113-124. PubMed ID: 27908837
[TBL] [Abstract][Full Text] [Related]
18. Single-molecule force spectroscopy study of interactions between angiotensin II type 1 receptor and different biased ligands in living cells.
Li W; Xu J; Kou X; Zhao R; Zhou W; Fang X
Anal Bioanal Chem; 2018 May; 410(14):3275-3284. PubMed ID: 29492619
[TBL] [Abstract][Full Text] [Related]
19. Cardiorenal actions of TRV120027, a novel ß-arrestin-biased ligand at the angiotensin II type I receptor, in healthy and heart failure canines: a novel therapeutic strategy for acute heart failure.
Boerrigter G; Lark MW; Whalen EJ; Soergel DG; Violin JD; Burnett JC
Circ Heart Fail; 2011 Nov; 4(6):770-8. PubMed ID: 21835984
[TBL] [Abstract][Full Text] [Related]
20. Ligand binding determinants for angiotensin II type 1 receptor from computer simulations.
Matsoukas MT; Cordomí A; Ríos S; Pardo L; Tselios T
J Chem Inf Model; 2013 Nov; 53(11):2874-83. PubMed ID: 24090110
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]