BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

360 related articles for article (PubMed ID: 26420866)

  • 1. Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases.
    Lohman JR; Ma M; Osipiuk J; Nocek B; Kim Y; Chang C; Cuff M; Mack J; Bigelow L; Li H; Endres M; Babnigg G; Joachimiak A; Phillips GN; Shen B
    Proc Natl Acad Sci U S A; 2015 Oct; 112(41):12693-8. PubMed ID: 26420866
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity.
    Tang Y; Lee TS; Kobayashi S; Khosla C
    Biochemistry; 2003 Jun; 42(21):6588-95. PubMed ID: 12767243
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei.
    Tang L; Yoon YJ; Choi CY; Hutchinson CR
    Gene; 1998 Aug; 216(2):255-65. PubMed ID: 9729415
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Phylogenomic analysis of modular polyketide synthases in actinomycetes and its application in product screening].
    Wang H; Liu N; Huang Y
    Wei Sheng Wu Xue Bao; 2010 Oct; 50(10):1293-304. PubMed ID: 21141462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phylogenomic analysis of polyketide synthase genes in actinomycetes: structural analysis of KS domains and modules of polyketide synthases.
    Sarwar S; Ahmed M; Hasnain S
    Int J Comput Biol Drug Des; 2012; 5(2):89-110. PubMed ID: 22854120
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase.
    Kim CY; Alekseyev VY; Chen AY; Tang Y; Cane DE; Khosla C
    Biochemistry; 2004 Nov; 43(44):13892-8. PubMed ID: 15518537
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multifunctional polyketide synthase genes identified by genomic survey of the symbiotic dinoflagellate, Symbiodinium minutum.
    Beedessee G; Hisata K; Roy MC; Satoh N; Shoguchi E
    BMC Genomics; 2015 Nov; 16():941. PubMed ID: 26573520
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metagenomic data reveals type I polyketide synthase distributions across biomes.
    Singh HW; Creamer KE; Chase AB; Klau LJ; Podell S; Jensen PR
    mSystems; 2023 Jun; 8(3):e0001223. PubMed ID: 37272717
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acyl-chain elongation drives ketosynthase substrate selectivity in trans-acyltransferase polyketide synthases.
    Jenner M; Afonso JP; Bailey HR; Frank S; Kampa A; Piel J; Oldham NJ
    Angew Chem Int Ed Engl; 2015 Feb; 54(6):1817-21. PubMed ID: 25529827
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Type I polyketide synthases that require discrete acyltransferases.
    Cheng YQ; Coughlin JM; Lim SK; Shen B
    Methods Enzymol; 2009; 459():165-86. PubMed ID: 19362640
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Engineering the acyltransferase domain of epothilone polyketide synthase to alter the substrate specificity.
    Wang H; Liang J; Yue Q; Li L; Shi Y; Chen G; Li YZ; Bian X; Zhang Y; Zhao G; Ding X
    Microb Cell Fact; 2021 Apr; 20(1):86. PubMed ID: 33882930
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Multimodular type I polyketide synthases in algae evolve by module duplications and displacement of AT domains in trans.
    Shelest E; Heimerl N; Fichtner M; Sasso S
    BMC Genomics; 2015 Nov; 16():1015. PubMed ID: 26611533
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase-Polyketide Synthase Interface for Leinamycin Biosynthesis.
    Huang Y; Tang GL; Pan G; Chang CY; Shen B
    Org Lett; 2016 Sep; 18(17):4288-91. PubMed ID: 27541042
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based dissociation of a type I polyketide synthase module.
    Chen AY; Cane DE; Khosla C
    Chem Biol; 2007 Jul; 14(7):784-92. PubMed ID: 17656315
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The toxic dinoflagellate Karenia brevis encodes novel type I-like polyketide synthases containing discrete catalytic domains.
    Monroe EA; Van Dolah FM
    Protist; 2008 Jul; 159(3):471-82. PubMed ID: 18467171
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase.
    Sabatini M; Comba S; Altabe S; Recio-Balsells AI; Labadie GR; Takano E; Gramajo H; Arabolaza A
    FEBS J; 2018 Dec; 285(23):4494-4511. PubMed ID: 30300504
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unique features of the ketosynthase domain in a nonribosomal peptide synthetase-polyketide synthase hybrid enzyme, tenuazonic acid synthetase 1.
    Yun CS; Nishimoto K; Motoyama T; Shimizu T; Hino T; Dohmae N; Nagano S; Osada H
    J Biol Chem; 2020 Aug; 295(33):11602-11612. PubMed ID: 32565425
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G; Anand S; Mohanty D
    J Biomol Struct Dyn; 2013; 31(1):17-29. PubMed ID: 22803697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production.
    Yuzawa S; Deng K; Wang G; Baidoo EE; Northen TR; Adams PD; Katz L; Keasling JD
    ACS Synth Biol; 2017 Jan; 6(1):139-147. PubMed ID: 27548700
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Iterative polyketide biosynthesis by modular polyketide synthases in bacteria.
    Chen H; Du L
    Appl Microbiol Biotechnol; 2016 Jan; 100(2):541-57. PubMed ID: 26549236
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.