These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism. Dyachok J; Earnest S; Iturraran EN; Cobb MH; Ross EM J Biol Chem; 2016 Oct; 291(43):22414-22426. PubMed ID: 27587390 [TBL] [Abstract][Full Text] [Related]
23. Rheb and Rags come together at the lysosome to activate mTORC1. Groenewoud MJ; Zwartkruis FJ Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162 [TBL] [Abstract][Full Text] [Related]
24. Nutrient regulation of the mTOR complex 1 signaling pathway. Kim SG; Buel GR; Blenis J Mol Cells; 2013 Jun; 35(6):463-73. PubMed ID: 23694989 [TBL] [Abstract][Full Text] [Related]
26. Amino acids suppress the expression of PAT1 on lysosomes via inducing the cleavage of a targeting signal. Ji X; Zhao L; Luo H; Zhang X; Jin Y; Liu W FEBS Lett; 2017 Aug; 591(15):2279-2289. PubMed ID: 28670736 [TBL] [Abstract][Full Text] [Related]
27. Recent advances in understanding of amino acid signaling to mTORC1 activation. Zhuang Y; Wang XX; He J; He S; Yin Y Front Biosci (Landmark Ed); 2019 Mar; 24(5):971-982. PubMed ID: 30844724 [TBL] [Abstract][Full Text] [Related]
28. Multiple amino acid sensing inputs to mTORC1. Shimobayashi M; Hall MN Cell Res; 2016 Jan; 26(1):7-20. PubMed ID: 26658722 [TBL] [Abstract][Full Text] [Related]
30. mTORC1: turning off is just as important as turning on. Benjamin D; Hall MN Cell; 2014 Feb; 156(4):627-8. PubMed ID: 24529368 [TBL] [Abstract][Full Text] [Related]
31. Cell biology. Making sense of amino acid sensing. Abraham RT Science; 2015 Jan; 347(6218):128-9. PubMed ID: 25574008 [No Abstract] [Full Text] [Related]
32. The emerging role of mTORC1 signaling in placental nutrient-sensing. Jansson T; Aye IL; Goberdhan DC Placenta; 2012 Nov; 33 Suppl 2(Suppl 2):e23-9. PubMed ID: 22687819 [TBL] [Abstract][Full Text] [Related]
33. Key mediators of intracellular amino acids signaling to mTORC1 activation. Duan Y; Li F; Tan K; Liu H; Li Y; Liu Y; Kong X; Tang Y; Wu G; Yin Y Amino Acids; 2015 May; 47(5):857-67. PubMed ID: 25701492 [TBL] [Abstract][Full Text] [Related]
35. Insights into the transport side of the human SLC38A9 transceptor. Scalise M; Galluccio M; Pochini L; Cosco J; Trotta M; Rebsamen M; Superti-Furga G; Indiveri C Biochim Biophys Acta Biomembr; 2019 Sep; 1861(9):1558-1567. PubMed ID: 31295473 [TBL] [Abstract][Full Text] [Related]
36. GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2. Ye J; Palm W; Peng M; King B; Lindsten T; Li MO; Koumenis C; Thompson CB Genes Dev; 2015 Nov; 29(22):2331-6. PubMed ID: 26543160 [TBL] [Abstract][Full Text] [Related]
37. The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids. Hoxhaj G; Caddye E; Najafov A; Houde VP; Johnson C; Dissanayake K; Toth R; Campbell DG; Prescott AR; MacKintosh C Elife; 2016 Apr; 5():. PubMed ID: 27244671 [TBL] [Abstract][Full Text] [Related]
38. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. Zoncu R; Bar-Peled L; Efeyan A; Wang S; Sancak Y; Sabatini DM Science; 2011 Nov; 334(6056):678-83. PubMed ID: 22053050 [TBL] [Abstract][Full Text] [Related]
39. Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. Matsui T; Fukuda M EMBO Rep; 2013 May; 14(5):450-7. PubMed ID: 23478338 [TBL] [Abstract][Full Text] [Related]
40. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Newton PT; Vuppalapati KK; Bouderlique T; Chagin AS Autophagy; 2015; 11(9):1594-607. PubMed ID: 26259639 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]