172 related articles for article (PubMed ID: 26434588)
1. Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex.
Patel B; Patel J; Cho JH; Manne S; Bonala S; Henske E; Roegiers F; Markiewski M; Karbowniczek M
Oncogene; 2016 Jun; 35(23):3027-36. PubMed ID: 26434588
[TBL] [Abstract][Full Text] [Related]
2. The evolutionarily conserved TSC/Rheb pathway activates Notch in tuberous sclerosis complex and Drosophila external sensory organ development.
Karbowniczek M; Zitserman D; Khabibullin D; Hartman T; Yu J; Morrison T; Nicolas E; Squillace R; Roegiers F; Henske EP
J Clin Invest; 2010 Jan; 120(1):93-102. PubMed ID: 20038815
[TBL] [Abstract][Full Text] [Related]
3. PAK2 is an effector of TSC1/2 signaling independent of mTOR and a potential therapeutic target for Tuberous Sclerosis Complex.
Alves MM; Fuhler GM; Queiroz KC; Scholma J; Goorden S; Anink J; Spek CA; Hoogeveen-Westerveld M; Bruno MJ; Nellist M; Elgersma Y; Aronica E; Peppelenbosch MP
Sci Rep; 2015 Sep; 5():14534. PubMed ID: 26412398
[TBL] [Abstract][Full Text] [Related]
4. Notch transactivates Rheb to maintain the multipotency of TSC-null cells.
Cho JH; Patel B; Bonala S; Manne S; Zhou Y; Vadrevu SK; Patel J; Peronaci M; Ghouse S; Henske EP; Roegiers F; Giannikou K; Kwiatkowski DJ; Mansouri H; Markiewski MM; White B; Karbowniczek M
Nat Commun; 2017 Nov; 8(1):1848. PubMed ID: 29184052
[TBL] [Abstract][Full Text] [Related]
5. Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease.
Astrinidis A; Henske EP
Oncogene; 2005 Nov; 24(50):7475-81. PubMed ID: 16288294
[TBL] [Abstract][Full Text] [Related]
6. Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.
Uhlmann EJ; Apicelli AJ; Baldwin RL; Burke SP; Bajenaru ML; Onda H; Kwiatkowski D; Gutmann DH
Oncogene; 2002 Jun; 21(25):4050-9. PubMed ID: 12037687
[TBL] [Abstract][Full Text] [Related]
7. Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways.
Kwiatkowski DJ; Manning BD
Hum Mol Genet; 2005 Oct; 14 Spec No. 2():R251-8. PubMed ID: 16244323
[TBL] [Abstract][Full Text] [Related]
8. Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase.
Hsu YC; Chern JJ; Cai Y; Liu M; Choi KW
Nature; 2007 Feb; 445(7129):785-8. PubMed ID: 17301792
[TBL] [Abstract][Full Text] [Related]
9. Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.
Uhlmann EJ; Li W; Scheidenhelm DK; Gau CL; Tamanoi F; Gutmann DH
Glia; 2004 Aug; 47(2):180-8. PubMed ID: 15185396
[TBL] [Abstract][Full Text] [Related]
10. Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment.
El-Hashemite N; Zhang H; Walker V; Hoffmeister KM; Kwiatkowski DJ
Cancer Res; 2004 May; 64(10):3436-43. PubMed ID: 15150095
[TBL] [Abstract][Full Text] [Related]
11. Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.
Li C; Zhang E; Sun Y; Lee PS; Zhan Y; Guo Y; Osorio JC; Rosas IO; Xu KF; Kwiatkowski DJ; Yu JJ
PLoS One; 2014; 9(10):e104809. PubMed ID: 25347447
[TBL] [Abstract][Full Text] [Related]
12. The analysis of mutations and exon deletions at TSC2 gene in angiomyolipomas associated with tuberous sclerosis complex.
Yang HM; Choi HJ; Hong DP; Joo SY; Lee NE; Song JY; Choi YL; Lee J; Choi D; Kim B; Park HJ; Park JB; Kim SJ
Exp Mol Pathol; 2014 Dec; 97(3):440-4. PubMed ID: 25281918
[TBL] [Abstract][Full Text] [Related]
13. Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123).
Crowell B; Lee GH; Nikolaeva I; Dal Pozzo V; D'Arcangelo G
eNeuro; 2015; 2(6):. PubMed ID: 26693177
[TBL] [Abstract][Full Text] [Related]
14. Therapeutic targeting of mTOR in tuberous sclerosis.
Sampson JR
Biochem Soc Trans; 2009 Feb; 37(Pt 1):259-64. PubMed ID: 19143643
[TBL] [Abstract][Full Text] [Related]
15. Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies.
Shah OJ; Wang Z; Hunter T
Curr Biol; 2004 Sep; 14(18):1650-6. PubMed ID: 15380067
[TBL] [Abstract][Full Text] [Related]
16. Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent.
Jaeschke A; Hartkamp J; Saitoh M; Roworth W; Nobukuni T; Hodges A; Sampson J; Thomas G; Lamb R
J Cell Biol; 2002 Oct; 159(2):217-24. PubMed ID: 12403809
[TBL] [Abstract][Full Text] [Related]
17. Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis.
Makovski V; Haklai R; Kloog Y
Int J Cancer; 2012 Mar; 130(6):1420-9. PubMed ID: 21500191
[TBL] [Abstract][Full Text] [Related]
18. Missense mutations to the TSC1 gene cause tuberous sclerosis complex.
Nellist M; van den Heuvel D; Schluep D; Exalto C; Goedbloed M; Maat-Kievit A; van Essen T; van Spaendonck-Zwarts K; Jansen F; Helderman P; Bartalini G; Vierimaa O; Penttinen M; van den Ende J; van den Ouweland A; Halley D
Eur J Hum Genet; 2009 Mar; 17(3):319-28. PubMed ID: 18830229
[TBL] [Abstract][Full Text] [Related]
19. Tuberous sclerosis and the kidney: from mesenchyme to epithelium, and beyond.
Henske EP
Pediatr Nephrol; 2005 Jul; 20(7):854-7. PubMed ID: 15856327
[TBL] [Abstract][Full Text] [Related]
20. The Codon 72
Cho JH; Patel B; Bonala S; Mansouri H; Manne S; Vadrevu SK; Ghouse S; Kung CP; Murphy ME; Astrinidis A; Henske EP; Kwiatkowski DJ; Markiewski MM; Karbowniczek M
Mol Cancer Res; 2019 Aug; 17(8):1639-1651. PubMed ID: 31088907
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]