255 related articles for article (PubMed ID: 26434591)
1. Metabolic targeting of oncogene MYC by selective activation of the proton-coupled monocarboxylate family of transporters.
Gan L; Xiu R; Ren P; Yue M; Su H; Guo G; Xiao D; Yu J; Jiang H; Liu H; Hu G; Qing G
Oncogene; 2016 Jun; 35(23):3037-48. PubMed ID: 26434591
[TBL] [Abstract][Full Text] [Related]
2. Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis.
Doherty JR; Yang C; Scott KE; Cameron MD; Fallahi M; Li W; Hall MA; Amelio AL; Mishra JK; Li F; Tortosa M; Genau HM; Rounbehler RJ; Lu Y; Dang CV; Kumar KG; Butler AA; Bannister TD; Hooper AT; Unsal-Kacmaz K; Roush WR; Cleveland JL
Cancer Res; 2014 Feb; 74(3):908-20. PubMed ID: 24285728
[TBL] [Abstract][Full Text] [Related]
3. [Monocarboxylate transporter 1 enhances the sensitivity of breast cancer cells to 3-bromopyruvate in vitro].
Li QX; Zhang P; Liu F; Wang XZ; Li L; Wang ZK; Jiang CC; Zheng HL; Liu H
Nan Fang Yi Ke Da Xue Xue Bao; 2017 May; 37(5):588-593. PubMed ID: 28539279
[TBL] [Abstract][Full Text] [Related]
4. MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.
Birsoy K; Wang T; Possemato R; Yilmaz OH; Koch CE; Chen WW; Hutchins AW; Gultekin Y; Peterson TR; Carette JE; Brummelkamp TR; Clish CB; Sabatini DM
Nat Genet; 2013 Jan; 45(1):104-8. PubMed ID: 23202129
[TBL] [Abstract][Full Text] [Related]
5. Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.
Wilde L; Roche M; Domingo-Vidal M; Tanson K; Philp N; Curry J; Martinez-Outschoorn U
Semin Oncol; 2017 Jun; 44(3):198-203. PubMed ID: 29248131
[TBL] [Abstract][Full Text] [Related]
6. Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition.
Khan A; Valli E; Lam H; Scott DA; Murray J; Hanssen KM; Eden G; Gamble LD; Pandher R; Flemming CL; Allan S; Osterman AL; Haber M; Norris MD; Fletcher JI; Yu DMT
Oncogene; 2020 Apr; 39(17):3555-3570. PubMed ID: 32123312
[TBL] [Abstract][Full Text] [Related]
7. Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
Pérez-Escuredo J; Dadhich RK; Dhup S; Cacace A; Van Hée VF; De Saedeleer CJ; Sboarina M; Rodriguez F; Fontenille MJ; Brisson L; Porporato PE; Sonveaux P
Cell Cycle; 2016; 15(1):72-83. PubMed ID: 26636483
[TBL] [Abstract][Full Text] [Related]
8. C-myc amplification altered the gene expression of ABC- and SLC-transporters in human breast epithelial cells.
Kang KW; Im YB; Go WJ; Han HK
Mol Pharm; 2009; 6(2):627-33. PubMed ID: 19239227
[TBL] [Abstract][Full Text] [Related]
9. Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration.
De Saedeleer CJ; Porporato PE; Copetti T; Pérez-Escuredo J; Payen VL; Brisson L; Feron O; Sonveaux P
Oncogene; 2014 Jul; 33(31):4060-8. PubMed ID: 24166504
[TBL] [Abstract][Full Text] [Related]
10. Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition.
Vander Linden C; Corbet C; Bastien E; Martherus R; Guilbaud C; Petit L; Wauthier L; Loriot A; De Smet C; Feron O
Cell Rep; 2021 Jun; 35(9):109202. PubMed ID: 34077729
[TBL] [Abstract][Full Text] [Related]
11. MCT4 as a potential therapeutic target for metastatic gastric cancer with peritoneal carcinomatosis.
Lee JY; Lee I; Chang WJ; Ahn SM; Lim SH; Kim HS; Yoo KH; Jung KS; Song HN; Cho JH; Kim SY; Kim KM; Lee S; Kim ST; Park SH; Lee J; Park JO; Park YS; Lim HY; Kang WK
Oncotarget; 2016 Jul; 7(28):43492-43503. PubMed ID: 27224918
[TBL] [Abstract][Full Text] [Related]
12. Exercise-induced changes in tumour LDH-B and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice.
Aveseh M; Nikooie R; Aminaie M
J Physiol; 2015 Jun; 593(12):2635-48. PubMed ID: 25907793
[TBL] [Abstract][Full Text] [Related]
13. Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter.
Payen VL; Hsu MY; Rädecke KS; Wyart E; Vazeille T; Bouzin C; Porporato PE; Sonveaux P
Cancer Res; 2017 Oct; 77(20):5591-5601. PubMed ID: 28827372
[TBL] [Abstract][Full Text] [Related]
14. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.
Hong CS; Graham NA; Gu W; Espindola Camacho C; Mah V; Maresh EL; Alavi M; Bagryanova L; Krotee PAL; Gardner BK; Behbahan IS; Horvath S; Chia D; Mellinghoff IK; Hurvitz SA; Dubinett SM; Critchlow SE; Kurdistani SK; Goodglick L; Braas D; Graeber TG; Christofk HR
Cell Rep; 2016 Feb; 14(7):1590-1601. PubMed ID: 26876179
[TBL] [Abstract][Full Text] [Related]
15. Impact of MYC in regulation of tumor cell metabolism.
Wahlström T; Henriksson MA
Biochim Biophys Acta; 2015 May; 1849(5):563-9. PubMed ID: 25038584
[TBL] [Abstract][Full Text] [Related]
16. Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors.
Van Hée VF; Labar D; Dehon G; Grasso D; Grégoire V; Muccioli GG; Frédérick R; Sonveaux P
Oncotarget; 2017 Apr; 8(15):24415-24428. PubMed ID: 28107190
[TBL] [Abstract][Full Text] [Related]
17. A Nonradioactive High-Throughput Screening-Compatible Cell-Based Assay to Identify Inhibitors of the Monocarboxylate Transporter Protein 1.
Bailey TL; Nieto A; McDonald PH
Assay Drug Dev Technol; 2019 Aug; 17(6):275-284. PubMed ID: 31532712
[No Abstract] [Full Text] [Related]
18. Targeting lactate transport suppresses in vivo breast tumour growth.
Morais-Santos F; Granja S; Miranda-Gonçalves V; Moreira AH; Queirós S; Vilaça JL; Schmitt FC; Longatto-Filho A; Paredes J; Baltazar F; Pinheiro C
Oncotarget; 2015 Aug; 6(22):19177-89. PubMed ID: 26203664
[TBL] [Abstract][Full Text] [Related]
19. Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2.
Xiao D; Ren P; Su H; Yue M; Xiu R; Hu Y; Liu H; Qing G
Oncotarget; 2015 Dec; 6(38):40655-66. PubMed ID: 26528759
[TBL] [Abstract][Full Text] [Related]
20. HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications.
Zhao Y; Li M; Yao X; Fei Y; Lin Z; Li Z; Cai K; Zhao Y; Luo Z
Cell Rep; 2020 Dec; 33(10):108487. PubMed ID: 33296645
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
