146 related articles for article (PubMed ID: 26435072)
1. Aryl Bis-Sulfonamide Inhibitors of IspF from Arabidopsis thaliana and Plasmodium falciparum.
Thelemann J; Illarionov B; Barylyuk K; Geist J; Kirchmair J; Schneider P; Anthore L; Root K; Trapp N; Bacher A; Witschel M; Zenobi R; Fischer M; Schneider G; Diederich F
ChemMedChem; 2015 Dec; 10(12):2090-8. PubMed ID: 26435072
[TBL] [Abstract][Full Text] [Related]
2. Thiazolopyrimidine inhibitors of 2-methylerythritol 2,4-cyclodiphosphate synthase (IspF) from Mycobacterium tuberculosis and Plasmodium falciparum.
Geist JG; Lauw S; Illarionova V; Illarionov B; Fischer M; Gräwert T; Rohdich F; Eisenreich W; Kaiser J; Groll M; Scheurer C; Wittlin S; Alonso-Gómez JL; Schweizer WB; Bacher A; Diederich F
ChemMedChem; 2010 Jul; 5(7):1092-101. PubMed ID: 20480490
[TBL] [Abstract][Full Text] [Related]
3. Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment.
O'Rourke PE; Kalinowska-Tłuścik J; Fyfe PK; Dawson A; Hunter WN
BMC Struct Biol; 2014 Jan; 14():1. PubMed ID: 24410837
[TBL] [Abstract][Full Text] [Related]
4. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
Singh VK; Ghosh I
FEBS Lett; 2013 Sep; 587(17):2806-17. PubMed ID: 23816706
[TBL] [Abstract][Full Text] [Related]
5. Design, Synthesis and Biological Evaluation of Novel Pyrazole Sulfonamide Derivatives as Potential AHAS Inhibitors.
Lv XH; Ren ZL; Liu H; Li HD; Li QS; Wang L; Zhang LS; Yao XK; Cao HQ
Chem Pharm Bull (Tokyo); 2018; 66(4):358-362. PubMed ID: 29607900
[TBL] [Abstract][Full Text] [Related]
6. 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity.
Bitok JK; Meyers CF
ACS Chem Biol; 2012 Oct; 7(10):1702-10. PubMed ID: 22839733
[TBL] [Abstract][Full Text] [Related]
7. Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy.
Crane CM; Kaiser J; Ramsden NL; Lauw S; Rohdich F; Eisenreich W; Hunter WN; Bacher A; Diederich F
Angew Chem Int Ed Engl; 2006 Feb; 45(7):1069-74. PubMed ID: 16392111
[No Abstract] [Full Text] [Related]
8. An in silico structural insights into Plasmodium LytB protein and its inhibition.
Bhuyan R; Nandy SK; Seal A
J Biomol Struct Dyn; 2015; 33(6):1198-210. PubMed ID: 25011618
[TBL] [Abstract][Full Text] [Related]
9. Functional evidence for the involvement of Arabidopsis IspF homolog in the nonmevalonate pathway of plastid isoprenoid biosynthesis.
Hsieh MH; Goodman HM
Planta; 2006 Mar; 223(4):779-84. PubMed ID: 16231155
[TBL] [Abstract][Full Text] [Related]
10. Design and synthesis of N-2,6-difluorophenyl-5-methoxyl-1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamide as acetohydroxyacid synthase inhibitor.
Chen CN; Lv LL; Ji FQ; Chen Q; Xu H; Niu CW; Xi Z; Yang GF
Bioorg Med Chem; 2009 Apr; 17(8):3011-7. PubMed ID: 19342247
[TBL] [Abstract][Full Text] [Related]
11. Synthesis, biological evaluation, and molecular docking studies of xanthone sulfonamides as ACAT inhibitors.
Li X; Zou Y; Zhao Q; Yang Y; Wu M; Huang T; Hu H; Wu Q
Chem Biol Drug Des; 2015 Mar; 85(3):394-403. PubMed ID: 25146964
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, structural characterization by IR, (1) H, (13) C, (15) N, 2D-NMR, X-ray diffraction and evaluation of a new class of phenylaminoacetic acid benzylidene hydrazines as pfENR inhibitors.
Samal RP; Khedkar VM; Pissurlenkar RR; Bwalya AG; Tasdemir D; Joshi RA; Rajamohanan PR; Puranik VG; Coutinho EC
Chem Biol Drug Des; 2013 Jun; 81(6):715-29. PubMed ID: 23398677
[TBL] [Abstract][Full Text] [Related]
13. Aryl bis-sulfonamides bind to the active site of a homotrimeric isoprenoid biosynthesis enzyme IspF and extract the essential divalent metal cation cofactor.
Root K; Barylyuk K; Schwab A; Thelemann J; Illarionov B; Geist JG; Gräwert T; Bacher A; Fischer M; Diederich F; Zenobi R
Chem Sci; 2018 Jul; 9(27):5976-5986. PubMed ID: 30079212
[TBL] [Abstract][Full Text] [Related]
14. Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD.
Kunfermann A; Witschel M; Illarionov B; Martin R; Rottmann M; Höffken HW; Seet M; Eisenreich W; Knölker HJ; Fischer M; Bacher A; Groll M; Diederich F
Angew Chem Int Ed Engl; 2014 Feb; 53(8):2235-9. PubMed ID: 24446431
[TBL] [Abstract][Full Text] [Related]
15. Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid.
Sosič I; Barreteau H; Simčič M; Sink R; Cesar J; Zega A; Grdadolnik SG; Contreras-Martel C; Dessen A; Amoroso A; Joris B; Blanot D; Gobec S
Eur J Med Chem; 2011 Jul; 46(7):2880-94. PubMed ID: 21524830
[TBL] [Abstract][Full Text] [Related]
16. Computer-aided design and synthesis of nonpeptidic plasmepsin II and IV inhibitors.
Luksch T; Chan NS; Brass S; Sotriffer CA; Klebe G; Diederich WE
ChemMedChem; 2008 Sep; 3(9):1323-36. PubMed ID: 18752222
[TBL] [Abstract][Full Text] [Related]
17. A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy.
Ramsden NL; Buetow L; Dawson A; Kemp LA; Ulaganathan V; Brenk R; Klebe G; Hunter WN
J Med Chem; 2009 Apr; 52(8):2531-42. PubMed ID: 19320487
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
Dufe VT; Qiu W; Müller IB; Hui R; Walter RD; Al-Karadaghi S
J Mol Biol; 2007 Oct; 373(1):167-77. PubMed ID: 17822713
[TBL] [Abstract][Full Text] [Related]
19. Identification of diverse natural products as falcipain-2 inhibitors through structure-based virtual screening.
Wang L; Zhang S; Zhu J; Zhu L; Liu X; Shan L; Huang J; Zhang W; Li H
Bioorg Med Chem Lett; 2014 Mar; 24(5):1261-4. PubMed ID: 24530004
[TBL] [Abstract][Full Text] [Related]
20. Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases.
Davies M; Heikkilä T; McConkey GA; Fishwick CW; Parsons MR; Johnson AP
J Med Chem; 2009 May; 52(9):2683-93. PubMed ID: 19351152
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
