227 related articles for article (PubMed ID: 26440750)
1. Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.
Wales TE; Hochrein JM; Morgan CR; Emert-Sedlak LA; Smithgall TE; Engen JR
Biochemistry; 2015 Oct; 54(41):6382-91. PubMed ID: 26440750
[TBL] [Abstract][Full Text] [Related]
2. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
Alvarado JJ; Tarafdar S; Yeh JI; Smithgall TE
J Biol Chem; 2014 Oct; 289(41):28539-53. PubMed ID: 25122770
[TBL] [Abstract][Full Text] [Related]
3. Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.
Jung J; Byeon IJ; Ahn J; Gronenborn AM
Proteins; 2011 May; 79(5):1609-22. PubMed ID: 21365684
[TBL] [Abstract][Full Text] [Related]
4. Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding.
Moroco JA; Alvarado JJ; Staudt RP; Shi H; Wales TE; Smithgall TE; Engen JR
J Mol Biol; 2018 Feb; 430(3):310-321. PubMed ID: 29258818
[TBL] [Abstract][Full Text] [Related]
5. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
Dutartre H; Harris M; Olive D; Collette Y
Virology; 1998 Aug; 247(2):200-11. PubMed ID: 9705913
[TBL] [Abstract][Full Text] [Related]
6. Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.
Narute PS; Smithgall TE
PLoS One; 2012; 7(2):e32561. PubMed ID: 22393415
[TBL] [Abstract][Full Text] [Related]
7. Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase.
Choi HJ; Smithgall TE
J Mol Biol; 2004 Nov; 343(5):1255-68. PubMed ID: 15491611
[TBL] [Abstract][Full Text] [Related]
8. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
Moarefi I; LaFevre-Bernt M; Sicheri F; Huse M; Lee CH; Kuriyan J; Miller WT
Nature; 1997 Feb; 385(6617):650-3. PubMed ID: 9024665
[TBL] [Abstract][Full Text] [Related]
9. Effector kinase coupling enables high-throughput screens for direct HIV-1 Nef antagonists with antiretroviral activity.
Emert-Sedlak LA; Narute P; Shu ST; Poe JA; Shi H; Yanamala N; Alvarado JJ; Lazo JS; Yeh JI; Johnston PA; Smithgall TE
Chem Biol; 2013 Jan; 20(1):82-91. PubMed ID: 23352142
[TBL] [Abstract][Full Text] [Related]
10. Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.
Hassan R; Suzu S; Hiyoshi M; Takahashi-Makise N; Ueno T; Agatsuma T; Akari H; Komano J; Takebe Y; Motoyoshi K; Okada S
J Cell Physiol; 2009 Nov; 221(2):458-68. PubMed ID: 19585521
[TBL] [Abstract][Full Text] [Related]
11. Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck.
Ye H; Choi HJ; Poe J; Smithgall TE
Biochemistry; 2004 Dec; 43(50):15775-84. PubMed ID: 15595833
[TBL] [Abstract][Full Text] [Related]
12. Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen.
Trible RP; Narute P; Emert-Sedlak LA; Alvarado JJ; Atkins K; Thomas L; Kodama T; Yanamala N; Korotchenko V; Day BW; Thomas G; Smithgall TE
Retrovirology; 2013 Nov; 10():135. PubMed ID: 24229420
[TBL] [Abstract][Full Text] [Related]
13. HIV-1 Nef-Induced Secretion of the Proinflammatory Protease TACE into Extracellular Vesicles Is Mediated by Raf-1 and Can Be Suppressed by Clinical Protein Kinase Inhibitors.
Zhao Z; Fagerlund R; Baur AS; Saksela K
J Virol; 2021 Apr; 95(9):. PubMed ID: 33597213
[TBL] [Abstract][Full Text] [Related]
14. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
Briggs SD; Sharkey M; Stevenson M; Smithgall TE
J Biol Chem; 1997 Jul; 272(29):17899-902. PubMed ID: 9218412
[TBL] [Abstract][Full Text] [Related]
15. Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compounds.
Emert-Sedlak L; Kodama T; Lerner EC; Dai W; Foster C; Day BW; Lazo JS; Smithgall TE
ACS Chem Biol; 2009 Nov; 4(11):939-47. PubMed ID: 19807124
[TBL] [Abstract][Full Text] [Related]
16. Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.
Kim MO; Suh HS; Si Q; Terman BI; Lee SC
J Virol; 2006 Jan; 80(1):62-72. PubMed ID: 16352531
[TBL] [Abstract][Full Text] [Related]
17. HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon.
Cornall A; Mak J; Greenway A; Tachedjian G
Viruses; 2013 Sep; 5(9):2235-52. PubMed ID: 24051604
[TBL] [Abstract][Full Text] [Related]
18. The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement.
Chutiwitoonchai N; Hiyoshi M; Mwimanzi P; Ueno T; Adachi A; Ode H; Sato H; Fackler OT; Okada S; Suzu S
PLoS One; 2011; 6(11):e27696. PubMed ID: 22110726
[TBL] [Abstract][Full Text] [Related]
19. Allosteric loss-of-function mutations in HIV-1 Nef from a long-term non-progressor.
Trible RP; Emert-Sedlak L; Wales TE; Ayyavoo V; Engen JR; Smithgall TE
J Mol Biol; 2007 Nov; 374(1):121-9. PubMed ID: 17920628
[TBL] [Abstract][Full Text] [Related]
20. Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.
Briggs SD; Lerner EC; Smithgall TE
Biochemistry; 2000 Jan; 39(3):489-95. PubMed ID: 10642173
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
