These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 26446620)

  • 1. Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.
    Brigui A; Hofmann L; Argüelles C; Sanial M; Holmgren RA; Plessis A
    Open Biol; 2015 Oct; 5(10):. PubMed ID: 26446620
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases.
    Li S; Li S; Wang B; Jiang J
    Sci Signal; 2018 Feb; 11(516):. PubMed ID: 29438012
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WW domain-mediated regulation and activation of E3 ubiquitin ligase Suppressor of Deltex.
    Yao W; Shan Z; Gu A; Fu M; Shi Z; Wen W
    J Biol Chem; 2018 Oct; 293(43):16697-16708. PubMed ID: 30213861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases.
    Jiang H; Thomas SN; Chen Z; Chiang CY; Cole PA
    J Biol Chem; 2019 Nov; 294(46):17421-17436. PubMed ID: 31578285
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover.
    Huang S; Zhang Z; Zhang C; Lv X; Zheng X; Chen Z; Sun L; Wang H; Zhu Y; Zhang J; Yang S; Lu Y; Sun Q; Tao Y; Liu F; Zhao Y; Chen D
    PLoS Biol; 2013 Nov; 11(11):e1001721. PubMed ID: 24302888
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover.
    Lu X; Liu S; Kornberg TB
    Genes Dev; 2006 Sep; 20(18):2539-51. PubMed ID: 16980583
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain.
    Bruce MC; Kanelis V; Fouladkou F; Debonneville A; Staub O; Rotin D
    Biochem J; 2008 Oct; 415(1):155-63. PubMed ID: 18498246
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation.
    Riling C; Kamadurai H; Kumar S; O'Leary CE; Wu KP; Manion EE; Ying M; Schulman BA; Oliver PM
    J Biol Chem; 2015 Sep; 290(39):23875-87. PubMed ID: 26245901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.
    Edwin F; Anderson K; Patel TB
    J Biol Chem; 2010 Jan; 285(1):255-64. PubMed ID: 19864419
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway.
    Bae SJ; Kim M; Kim SH; Kwon YE; Lee JH; Kim J; Chung CH; Lee WJ; Seol JH
    Nat Commun; 2015 Feb; 6():6314. PubMed ID: 25692647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases.
    Rotin D; Staub O; Haguenauer-Tsapis R
    J Membr Biol; 2000 Jul; 176(1):1-17. PubMed ID: 10882424
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.
    Sakata T; Sakaguchi H; Tsuda L; Higashitani A; Aigaki T; Matsuno K; Hayashi S
    Curr Biol; 2004 Dec; 14(24):2228-36. PubMed ID: 15620649
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.
    Lin Q; Wang J; Childress C; Sudol M; Carey DJ; Yang W
    Mol Cell Biol; 2010 Mar; 30(6):1541-54. PubMed ID: 20086093
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins.
    Mund T; Pelham HR
    EMBO Rep; 2009 May; 10(5):501-7. PubMed ID: 19343052
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Specificity and autoregulation of Notch binding by tandem WW domains in suppressor of Deltex.
    Jennings MD; Blankley RT; Baron M; Golovanov AP; Avis JM
    J Biol Chem; 2007 Sep; 282(39):29032-29042. PubMed ID: 17656366
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition.
    Wang J; Peng Q; Lin Q; Childress C; Carey D; Yang W
    J Biol Chem; 2010 Apr; 285(16):12279-88. PubMed ID: 20172859
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.
    Persaud A; Alberts P; Hayes M; Guettler S; Clarke I; Sicheri F; Dirks P; Ciruna B; Rotin D
    EMBO J; 2011 Jul; 30(16):3259-73. PubMed ID: 21765395
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases.
    Winberg G; Matskova L; Chen F; Plant P; Rotin D; Gish G; Ingham R; Ernberg I; Pawson T
    Mol Cell Biol; 2000 Nov; 20(22):8526-35. PubMed ID: 11046148
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polarized sorting of Patched enables cytoneme-mediated Hedgehog reception in the Drosophila wing disc.
    González-Méndez L; Gradilla AC; Sánchez-Hernández D; González E; Aguirre-Tamaral A; Jiménez-Jiménez C; Guerra M; Aguilar G; Andrés G; Falcón-Pérez JM; Guerrero I
    EMBO J; 2020 Jun; 39(11):e103629. PubMed ID: 32311148
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.