These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
1179 related articles for article (PubMed ID: 26449471)
1. Sestrin2 is a leucine sensor for the mTORC1 pathway. Wolfson RL; Chantranupong L; Saxton RA; Shen K; Scaria SM; Cantor JR; Sabatini DM Science; 2016 Jan; 351(6268):43-8. PubMed ID: 26449471 [TBL] [Abstract][Full Text] [Related]
2. Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway. Saxton RA; Knockenhauer KE; Wolfson RL; Chantranupong L; Pacold ME; Wang T; Schwartz TU; Sabatini DM Science; 2016 Jan; 351(6268):53-8. PubMed ID: 26586190 [TBL] [Abstract][Full Text] [Related]
3. Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation. Kimball SR; Gordon BS; Moyer JE; Dennis MD; Jefferson LS Cell Signal; 2016 Aug; 28(8):896-906. PubMed ID: 27010498 [TBL] [Abstract][Full Text] [Related]
4. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Kim JS; Ro SH; Kim M; Park HW; Semple IA; Park H; Cho US; Wang W; Guan KL; Karin M; Lee JH Sci Rep; 2015 Mar; 5():9502. PubMed ID: 25819761 [TBL] [Abstract][Full Text] [Related]
5. The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway. Chantranupong L; Scaria SM; Saxton RA; Gygi MP; Shen K; Wyant GA; Wang T; Harper JW; Gygi SP; Sabatini DM Cell; 2016 Mar; 165(1):153-164. PubMed ID: 26972053 [TBL] [Abstract][Full Text] [Related]
6. The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1. Chantranupong L; Wolfson RL; Orozco JM; Saxton RA; Scaria SM; Bar-Peled L; Spooner E; Isasa M; Gygi SP; Sabatini DM Cell Rep; 2014 Oct; 9(1):1-8. PubMed ID: 25263562 [TBL] [Abstract][Full Text] [Related]
7. A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1. Bar-Peled L; Chantranupong L; Cherniack AD; Chen WW; Ottina KA; Grabiner BC; Spear ED; Carter SL; Meyerson M; Sabatini DM Science; 2013 May; 340(6136):1100-6. PubMed ID: 23723238 [TBL] [Abstract][Full Text] [Related]
8. Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway. Lee M; Kim JH; Yoon I; Lee C; Fallahi Sichani M; Kang JS; Kang J; Guo M; Lee KY; Han G; Kim S; Han JM Proc Natl Acad Sci U S A; 2018 Jun; 115(23):E5279-E5288. PubMed ID: 29784813 [TBL] [Abstract][Full Text] [Related]
11. Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids. Averous J; Lambert-Langlais S; Carraro V; Gourbeyre O; Parry L; B'Chir W; Muranishi Y; Jousse C; Bruhat A; Maurin AC; Proud CG; Fafournoux P Cell Signal; 2014 Sep; 26(9):1918-27. PubMed ID: 24793303 [TBL] [Abstract][Full Text] [Related]
12. GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2. Ye J; Palm W; Peng M; King B; Lindsten T; Li MO; Koumenis C; Thompson CB Genes Dev; 2015 Nov; 29(22):2331-6. PubMed ID: 26543160 [TBL] [Abstract][Full Text] [Related]
13. SZT2 dictates GATOR control of mTORC1 signalling. Peng M; Yin N; Li MO Nature; 2017 Mar; 543(7645):433-437. PubMed ID: 28199315 [TBL] [Abstract][Full Text] [Related]
14. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Wolfson RL; Chantranupong L; Wyant GA; Gu X; Orozco JM; Shen K; Condon KJ; Petri S; Kedir J; Scaria SM; Abu-Remaileh M; Frankel WN; Sabatini DM Nature; 2017 Mar; 543(7645):438-442. PubMed ID: 28199306 [TBL] [Abstract][Full Text] [Related]
15. Sestrins inhibit mTORC1 kinase activation through the GATOR complex. Parmigiani A; Nourbakhsh A; Ding B; Wang W; Kim YC; Akopiants K; Guan KL; Karin M; Budanov AV Cell Rep; 2014 Nov; 9(4):1281-91. PubMed ID: 25457612 [TBL] [Abstract][Full Text] [Related]
16. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Jewell JL; Kim YC; Russell RC; Yu FX; Park HW; Plouffe SW; Tagliabracci VS; Guan KL Science; 2015 Jan; 347(6218):194-8. PubMed ID: 25567907 [TBL] [Abstract][Full Text] [Related]
17. Ring domains are essential for GATOR2-dependent mTORC1 activation. Jiang C; Dai X; He S; Zhou H; Fang L; Guo J; Liu S; Zhang T; Pan W; Yu H; Fu T; Li D; Inuzuka H; Wang P; Xiao J; Wei W Mol Cell; 2023 Jan; 83(1):74-89.e9. PubMed ID: 36528027 [TBL] [Abstract][Full Text] [Related]
18. Effects of Leucine Ingestion and Contraction on the Sestrin/GATOR2 Pathway and mTORC1 Activation in Rat Fast-Twitch muscle. Kanzaki K; Wada M J Nutr; 2023 Aug; 153(8):2228-2236. PubMed ID: 37328110 [TBL] [Abstract][Full Text] [Related]
19. Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation. Suryawan A; Davis TA J Nutr; 2018 Jun; 148(6):825-833. PubMed ID: 29796625 [TBL] [Abstract][Full Text] [Related]
20. Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation. Kwak SS; Kang KH; Kim S; Lee S; Lee JH; Kim JW; Byun B; Meadows GG; Joe CO Cell Signal; 2016 Feb; 28(2):32-41. PubMed ID: 26582740 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]