313 related articles for article (PubMed ID: 26452386)
1. Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer.
Broude EV; Győrffy B; Chumanevich AA; Chen M; McDermott MS; Shtutman M; Catroppo JF; Roninson IB
Curr Cancer Drug Targets; 2015; 15(8):739-49. PubMed ID: 26452386
[TBL] [Abstract][Full Text] [Related]
2. Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of cyclin C-CDK8/19.
Park MJ; Shen H; Spaeth JM; Tolvanen JH; Failor C; Knudtson JF; McLaughlin J; Halder SK; Yang Q; Bulun SE; Al-Hendy A; Schenken RS; Aaltonen LA; Boyer TG
J Biol Chem; 2018 Mar; 293(13):4870-4882. PubMed ID: 29440396
[TBL] [Abstract][Full Text] [Related]
3. Mediator kinase module proteins, genetic alterations and expression of super-enhancer regulated genes in colorectal cancer.
Voutsadakis IA
Pharmacol Rep; 2024 Jun; 76(3):535-556. PubMed ID: 38602606
[TBL] [Abstract][Full Text] [Related]
4. Mutation analysis of components of the Mediator kinase module in MED12 mutation-negative uterine leiomyomas.
Mäkinen N; Heinonen HR; Sjöberg J; Taipale J; Vahteristo P; Aaltonen LA
Br J Cancer; 2014 Apr; 110(9):2246-9. PubMed ID: 24642626
[TBL] [Abstract][Full Text] [Related]
5. Cyclin-dependent kinase 8 module expression profiling reveals requirement of mediator subunits 12 and 13 for transcription of Serpent-dependent innate immunity genes in Drosophila.
Kuuluvainen E; Hakala H; Havula E; Sahal Estimé M; Rämet M; Hietakangas V; Mäkelä TP
J Biol Chem; 2014 Jun; 289(23):16252-61. PubMed ID: 24778181
[TBL] [Abstract][Full Text] [Related]
6. Identifying Cancers Impacted by CDK8/19.
Roninson IB; Győrffy B; Mack ZT; Shtil AA; Shtutman MS; Chen M; Broude EV
Cells; 2019 Aug; 8(8):. PubMed ID: 31382571
[TBL] [Abstract][Full Text] [Related]
7. De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder.
Calpena E; Hervieu A; Kaserer T; Swagemakers SMA; Goos JAC; Popoola O; Ortiz-Ruiz MJ; Barbaro-Dieber T; Bownass L; Brilstra EH; Brimble E; Foulds N; Grebe TA; Harder AVE; Lees MM; Monaghan KG; Newbury-Ecob RA; Ong KR; Osio D; Reynoso Santos FJ; Ruzhnikov MRZ; Telegrafi A; van Binsbergen E; van Dooren MF; ; van der Spek PJ; Blagg J; Twigg SRF; Mathijssen IMJ; Clarke PA; Wilkie AOM
Am J Hum Genet; 2019 Apr; 104(4):709-720. PubMed ID: 30905399
[TBL] [Abstract][Full Text] [Related]
8. Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells.
Kuuluvainen E; Domènech-Moreno E; Niemelä EH; Mäkelä TP
Mol Cell Biol; 2018 Jun; 38(11):. PubMed ID: 29507187
[TBL] [Abstract][Full Text] [Related]
9. Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.
Brägelmann J; Klümper N; Offermann A; von Mässenhausen A; Böhm D; Deng M; Queisser A; Sanders C; Syring I; Merseburger AS; Vogel W; Sievers E; Vlasic I; Carlsson J; Andrén O; Brossart P; Duensing S; Svensson MA; Adler D; Kirfel J; Perner S
Clin Cancer Res; 2017 Apr; 23(7):1829-1840. PubMed ID: 27678455
[No Abstract] [Full Text] [Related]
10. Regulatory functions of the Mediator kinases CDK8 and CDK19.
Fant CB; Taatjes DJ
Transcription; 2019 Apr; 10(2):76-90. PubMed ID: 30585107
[TBL] [Abstract][Full Text] [Related]
11. A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response.
Audetat KA; Galbraith MD; Odell AT; Lee T; Pandey A; Espinosa JM; Dowell RD; Taatjes DJ
Mol Cell Biol; 2017 Jul; 37(13):. PubMed ID: 28416637
[TBL] [Abstract][Full Text] [Related]
12. Distinct effects of CDK8 module subunits on cellular growth and proliferation in
Li X; Liu M; Xing Y; Niu Y; Liu TH; Sun JL; Liu Y; Hemba-Waduge RU; Ji JY
bioRxiv; 2024 May; ():. PubMed ID: 38746212
[TBL] [Abstract][Full Text] [Related]
13. The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription.
Li X; Liu M; Ren X; Loncle N; Wang Q; Hemba-Waduge RU; Yu SH; Boube M; Bourbon HG; Ni JQ; Ji JY
PLoS Genet; 2020 May; 16(5):e1008832. PubMed ID: 32463833
[TBL] [Abstract][Full Text] [Related]
14. A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
Klatt F; Leitner A; Kim IV; Ho-Xuan H; Schneider EV; Langhammer F; Weinmann R; Müller MR; Huber R; Meister G; Kuhn CD
Proc Natl Acad Sci U S A; 2020 Feb; 117(6):2894-2905. PubMed ID: 31988137
[TBL] [Abstract][Full Text] [Related]
15. Increased mediator complex subunit CDK19 expression associates with aggressive prostate cancer.
Becker F; Joerg V; Hupe MC; Roth D; Krupar R; Lubczyk V; Kuefer R; Sailer V; Duensing S; Kirfel J; Merseburger AS; Brägelmann J; Perner S; Offermann A
Int J Cancer; 2020 Jan; 146(2):577-588. PubMed ID: 31271443
[TBL] [Abstract][Full Text] [Related]
16. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions.
Steinparzer I; Sedlyarov V; Rubin JD; Eislmayr K; Galbraith MD; Levandowski CB; Vcelkova T; Sneezum L; Wascher F; Amman F; Kleinova R; Bender H; Andrysik Z; Espinosa JM; Superti-Furga G; Dowell RD; Taatjes DJ; Kovarik P
Mol Cell; 2019 Nov; 76(3):485-499.e8. PubMed ID: 31495563
[TBL] [Abstract][Full Text] [Related]
17. CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.
Chen M; Li J; Zhang L; Wang L; Cheng C; Ji H; Altilia S; Ding X; Cai G; Altomare D; Shtutman M; Byrum SD; Mackintosh SG; Feoktistov A; Soshnikova N; Mogila VA; Tatarskiy V; Erokhin M; Chetverina D; Prawira A; Ni Y; Urban S; McInnes C; Broude EV; Roninson IB
Nucleic Acids Res; 2023 Aug; 51(14):7288-7313. PubMed ID: 37378433
[TBL] [Abstract][Full Text] [Related]
18. Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
Turunen M; Spaeth JM; Keskitalo S; Park MJ; Kivioja T; Clark AD; Mäkinen N; Gao F; Palin K; Nurkkala H; Vähärautio A; Aavikko M; Kämpjärvi K; Vahteristo P; Kim CA; Aaltonen LA; Varjosalo M; Taipale J; Boyer TG
Cell Rep; 2014 May; 7(3):654-60. PubMed ID: 24746821
[TBL] [Abstract][Full Text] [Related]
19. Dual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation.
Papadopoulou T; Kaymak A; Sayols S; Richly H
Cell Cycle; 2016 Jun; 15(11):1479-93. PubMed ID: 27096886
[TBL] [Abstract][Full Text] [Related]
20. MED12 somatic mutations encompassing exon 2 associated with benign breast fibroadenomas and not breast carcinoma in Indian women.
Darooei M; Khan F; Rehan M; Zubeda S; Jeyashanker E; Annapurna S; Shah A; Maddali S; Hasan Q
J Cell Biochem; 2019 Jan; 120(1):182-191. PubMed ID: 30230586
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
