194 related articles for article (PubMed ID: 26455327)
1. PDK1 promotes tumor growth and metastasis in a spontaneous breast cancer model.
Du J; Yang M; Chen S; Li D; Chang Z; Dong Z
Oncogene; 2016 Jun; 35(25):3314-23. PubMed ID: 26455327
[TBL] [Abstract][Full Text] [Related]
2. PDK1 signaling toward PLK1-MYC activation confers oncogenic transformation, tumor-initiating cell activation, and resistance to mTOR-targeted therapy.
Tan J; Li Z; Lee PL; Guan P; Aau MY; Lee ST; Feng M; Lim CZ; Lee EY; Wee ZN; Lim YC; Karuturi RK; Yu Q
Cancer Discov; 2013 Oct; 3(10):1156-71. PubMed ID: 23887393
[TBL] [Abstract][Full Text] [Related]
3. IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation.
Guo JP; Coppola D; Cheng JQ
J Biol Chem; 2011 Oct; 286(43):37389-98. PubMed ID: 21908616
[TBL] [Abstract][Full Text] [Related]
4. PDK1 is a potential therapeutic target against angiosarcoma cells.
Wada M; Horinaka M; Yasuda S; Masuzawa M; Sakai T; Katoh N
J Dermatol Sci; 2015 Apr; 78(1):44-50. PubMed ID: 25726712
[TBL] [Abstract][Full Text] [Related]
5. Down-regulation of 3-phosphoinositide-dependent protein kinase-1 levels inhibits migration and experimental metastasis of human breast cancer cells.
Liu Y; Wang J; Wu M; Wan W; Sun R; Yang D; Sun X; Ma D; Ying G; Zhang N
Mol Cancer Res; 2009 Jun; 7(6):944-54. PubMed ID: 19531564
[TBL] [Abstract][Full Text] [Related]
6. Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer.
Emmanouilidi A; Fyffe CA; Ferro R; Edling CE; Capone E; Sestito S; Rapposelli S; Lattanzio R; Iacobelli S; Sala G; Maffucci T; Falasca M
J Exp Clin Cancer Res; 2019 May; 38(1):191. PubMed ID: 31088502
[TBL] [Abstract][Full Text] [Related]
7. Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways.
Schmitt DL; Sundaram A; Jeon M; Luu BT; An S
PLoS One; 2018; 13(4):e0195989. PubMed ID: 29668719
[TBL] [Abstract][Full Text] [Related]
8. FKBP4 connects mTORC2 and PI3K to activate the PDK1/Akt-dependent cell proliferation signaling in breast cancer.
Mangé A; Coyaud E; Desmetz C; Laurent E; Béganton B; Coopman P; Raught B; Solassol J
Theranostics; 2019; 9(23):7003-7015. PubMed ID: 31660083
[No Abstract] [Full Text] [Related]
9. RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.
Kim DW; Hwang JH; Suh JM; Kim H; Song JH; Hwang ES; Hwang IY; Park KC; Chung HK; Kim JM; Park J; Hemmings BA; Shong M
Mol Endocrinol; 2003 Jul; 17(7):1382-94. PubMed ID: 12738763
[TBL] [Abstract][Full Text] [Related]
10. 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.
Maurer M; Su T; Saal LH; Koujak S; Hopkins BD; Barkley CR; Wu J; Nandula S; Dutta B; Xie Y; Chin YR; Kim DI; Ferris JS; Gruvberger-Saal SK; Laakso M; Wang X; Memeo L; Rojtman A; Matos T; Yu JS; Cordon-Cardo C; Isola J; Terry MB; Toker A; Mills GB; Zhao JJ; Murty VV; Hibshoosh H; Parsons R
Cancer Res; 2009 Aug; 69(15):6299-306. PubMed ID: 19602588
[TBL] [Abstract][Full Text] [Related]
11. PPARδ activation acts cooperatively with 3-phosphoinositide-dependent protein kinase-1 to enhance mammary tumorigenesis.
Pollock CB; Yin Y; Yuan H; Zeng X; King S; Li X; Kopelovich L; Albanese C; Glazer RI
PLoS One; 2011 Jan; 6(1):e16215. PubMed ID: 21297860
[TBL] [Abstract][Full Text] [Related]
12. Autophagy and 3-Phosphoinositide-Dependent Kinase 1 (PDK1)-Related Kinome in Pagetic Osteoclasts.
McManus S; Bisson M; Chamberland R; Roy M; Nazari S; Roux S
J Bone Miner Res; 2016 Jul; 31(7):1334-43. PubMed ID: 26848537
[TBL] [Abstract][Full Text] [Related]
13. The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis.
Ooms LM; Binge LC; Davies EM; Rahman P; Conway JR; Gurung R; Ferguson DT; Papa A; Fedele CG; Vieusseux JL; Chai RC; Koentgen F; Price JT; Tiganis T; Timpson P; McLean CA; Mitchell CA
Cancer Cell; 2015 Aug; 28(2):155-69. PubMed ID: 26267533
[TBL] [Abstract][Full Text] [Related]
14. 3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases.
Xie Z; Yuan H; Yin Y; Zeng X; Bai R; Glazer RI
BMC Cancer; 2006 Mar; 6():77. PubMed ID: 16551362
[TBL] [Abstract][Full Text] [Related]
15. Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth.
Yen L; Cao Z; Wu X; Ingalla ER; Baron C; Young LJ; Gregg JP; Cardiff RD; Borowsky AD; Sweeney C; Carraway KL
Cancer Res; 2006 Dec; 66(23):11279-86. PubMed ID: 17145873
[TBL] [Abstract][Full Text] [Related]
16. Ridaforolimus (MK-8669) synergizes with Dalotuzumab (MK-0646) in hormone-sensitive breast cancer.
Becker MA; Hou X; Tienchaianada P; Haines BB; Harrington SC; Weroha SJ; Sathyanarayanan S; Haluska P
BMC Cancer; 2016 Oct; 16(1):814. PubMed ID: 27765027
[TBL] [Abstract][Full Text] [Related]
17. Differential roles of phosphoinositide-dependent protein kinase-1 and akt1 expression and phosphorylation in breast cancer cell resistance to Paclitaxel, Doxorubicin, and gemcitabine.
Liang K; Lu Y; Li X; Zeng X; Glazer RI; Mills GB; Fan Z
Mol Pharmacol; 2006 Sep; 70(3):1045-52. PubMed ID: 16782806
[TBL] [Abstract][Full Text] [Related]
18. Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinositol-dependent kinase 1 regulates glycogen synthase kinase 3 activity: a novel mechanism of Akt activation.
Miralem T; Lerner-Marmarosh N; Gibbs PE; Jenkins JL; Heimiller C; Maines MD
FASEB J; 2016 Aug; 30(8):2926-44. PubMed ID: 27166089
[TBL] [Abstract][Full Text] [Related]
19. PDK1 in NF-κB signaling is a target of Xanthium strumarium methanolic extract-mediated anti-inflammatory activities.
Hossen MJ; Cho JY; Kim D
J Ethnopharmacol; 2016 Aug; 190():251-60. PubMed ID: 27286918
[TBL] [Abstract][Full Text] [Related]
20. PDK1-AKT signaling pathway regulates the expression and function of cardiac hyperpolarization-activated cyclic nucleotide-modulated channels.
Han Z; Wu X; Gao Y; Liu X; Bai J; Gu R; Lan R; Xu B; Xu W
Life Sci; 2020 Jun; 250():117546. PubMed ID: 32184125
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
