BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 26459098)

  • 21. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
    Yan T; Desai AB; Jacobberger JW; Sramkoski RM; Loh T; Kinsella TJ
    Mol Cancer Ther; 2004 Sep; 3(9):1147-57. PubMed ID: 15367709
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer.
    Abdel-Fatah TM; Middleton FK; Arora A; Agarwal D; Chen T; Moseley PM; Perry C; Doherty R; Chan S; Green AR; Rakha E; Ball G; Ellis IO; Curtin NJ; Madhusudan S
    Mol Oncol; 2015 Mar; 9(3):569-85. PubMed ID: 25468710
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression.
    Di Benedetto A; Ercolani C; Mottolese M; Sperati F; Pizzuti L; Vici P; Terrenato I; Shaaban AM; Humphries MP; Di Lauro L; Barba M; Vitale I; Ciliberto G; Speirs V; De Maria R; Maugeri-Saccà M
    Sci Rep; 2017 Aug; 7(1):8078. PubMed ID: 28808232
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Evaluation of CHK1 activation in vulvar squamous cell carcinoma and its potential as a therapeutic target in vitro.
    Wang Z; Førsund MS; Trope CG; Nesland JM; Holm R; Slipicevic A
    Cancer Med; 2018 Aug; 7(8):3955-3964. PubMed ID: 29963769
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells.
    Wang FZ; Fei HR; Cui YJ; Sun YK; Li ZM; Wang XY; Yang XY; Zhang JG; Sun BL
    Apoptosis; 2014 Sep; 19(9):1389-98. PubMed ID: 24928205
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.
    Lee HJ; Hwang HI; Jang YJ
    Cell Cycle; 2010 Jun; 9(12):2389-98. PubMed ID: 20581453
    [TBL] [Abstract][Full Text] [Related]  

  • 27. mTORC1 and DNA-PKcs as novel molecular determinants of sensitivity to Chk1 inhibition.
    Massey AJ; Stephens P; Rawlinson R; McGurk L; Plummer R; Curtin NJ
    Mol Oncol; 2016 Jan; 10(1):101-12. PubMed ID: 26471831
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells.
    Takagaki K; Katsuma S; Kaminishi Y; Horio T; Tanaka T; Ohgi T; Yano J
    Genes Cells; 2005 Feb; 10(2):97-106. PubMed ID: 15676021
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Targeting radioresistant breast cancer cells by single agent CHK1 inhibitor via enhancing replication stress.
    Zhang Y; Lai J; Du Z; Gao J; Yang S; Gorityala S; Xiong X; Deng O; Ma Z; Yan C; Susana G; Xu Y; Zhang J
    Oncotarget; 2016 Jun; 7(23):34688-702. PubMed ID: 27167194
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
    Syljuåsen RG; Sørensen CS; Hansen LT; Fugger K; Lundin C; Johansson F; Helleday T; Sehested M; Lukas J; Bartek J
    Mol Cell Biol; 2005 May; 25(9):3553-62. PubMed ID: 15831461
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.
    Smith J; Tho LM; Xu N; Gillespie DA
    Adv Cancer Res; 2010; 108():73-112. PubMed ID: 21034966
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting ataxia telangiectasia-mutated- and Rad3-related kinase (ATR) in PTEN-deficient breast cancers for personalized therapy.
    Al-Subhi N; Ali R; Abdel-Fatah T; Moseley PM; Chan SYT; Green AR; Ellis IO; Rakha EA; Madhusudan S
    Breast Cancer Res Treat; 2018 Jun; 169(2):277-286. PubMed ID: 29396668
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
    Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
    [TBL] [Abstract][Full Text] [Related]  

  • 34. DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.
    Arlander SJ; Greene BT; Innes CL; Paules RS
    Cancer Res; 2008 Jan; 68(1):89-97. PubMed ID: 18172300
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells.
    Rodríguez-Bravo V; Guaita-Esteruelas S; Florensa R; Bachs O; Agell N
    Cancer Res; 2006 Sep; 66(17):8672-9. PubMed ID: 16951182
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy.
    Prevo R; Fokas E; Reaper PM; Charlton PA; Pollard JR; McKenna WG; Muschel RJ; Brunner TB
    Cancer Biol Ther; 2012 Sep; 13(11):1072-81. PubMed ID: 22825331
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.
    Baranski Z; Booij TH; Cleton-Jansen AM; Price LS; van de Water B; Bovée JV; Hogendoorn PC; Danen EH
    J Pathol; 2015 Jul; 236(3):348-59. PubMed ID: 25757065
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Development of pharmacodynamic biomarkers for ATR inhibitors.
    Chen T; Middleton FK; Falcon S; Reaper PM; Pollard JR; Curtin NJ
    Mol Oncol; 2015 Feb; 9(2):463-72. PubMed ID: 25459351
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer.
    Alshareeda AT; Negm OH; Albarakati N; Green AR; Nolan C; Sultana R; Madhusudan S; Benhasouna A; Tighe P; Ellis IO; Rakha EA
    Breast Cancer Res Treat; 2013 Jun; 139(2):301-10. PubMed ID: 23624778
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Cdk inhibition in human cells compromises chk1 function and activates a DNA damage response.
    Maude SL; Enders GH
    Cancer Res; 2005 Feb; 65(3):780-6. PubMed ID: 15705874
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.