237 related articles for article (PubMed ID: 26463209)
1. DNA Replication Dynamics of the GGGGCC Repeat of the C9orf72 Gene.
Thys RG; Wang YH
J Biol Chem; 2015 Nov; 290(48):28953-62. PubMed ID: 26463209
[TBL] [Abstract][Full Text] [Related]
2. The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures.
Reddy K; Zamiri B; Stanley SYR; Macgregor RB; Pearson CE
J Biol Chem; 2013 Apr; 288(14):9860-9866. PubMed ID: 23423380
[TBL] [Abstract][Full Text] [Related]
3. TMPyP4 porphyrin distorts RNA G-quadruplex structures of the disease-associated r(GGGGCC)n repeat of the C9orf72 gene and blocks interaction of RNA-binding proteins.
Zamiri B; Reddy K; Macgregor RB; Pearson CE
J Biol Chem; 2014 Feb; 289(8):4653-9. PubMed ID: 24371143
[TBL] [Abstract][Full Text] [Related]
4. C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms RNA G-quadruplexes.
Fratta P; Mizielinska S; Nicoll AJ; Zloh M; Fisher EM; Parkinson G; Isaacs AM
Sci Rep; 2012; 2():1016. PubMed ID: 23264878
[TBL] [Abstract][Full Text] [Related]
5. G-quadruplex-binding small molecules ameliorate
Simone R; Balendra R; Moens TG; Preza E; Wilson KM; Heslegrave A; Woodling NS; Niccoli T; Gilbert-Jaramillo J; Abdelkarim S; Clayton EL; Clarke M; Konrad MT; Nicoll AJ; Mitchell JS; Calvo A; Chio A; Houlden H; Polke JM; Ismail MA; Stephens CE; Vo T; Farahat AA; Wilson WD; Boykin DW; Zetterberg H; Partridge L; Wray S; Parkinson G; Neidle S; Patani R; Fratta P; Isaacs AM
EMBO Mol Med; 2018 Jan; 10(1):22-31. PubMed ID: 29113975
[TBL] [Abstract][Full Text] [Related]
6. ALS and FTD linked GGGGCC-repeat containing DNA oligonucleotide folds into two distinct G-quadruplexes.
Brčić J; Plavec J
Biochim Biophys Acta Gen Subj; 2017 May; 1861(5 Pt B):1237-1245. PubMed ID: 27856299
[TBL] [Abstract][Full Text] [Related]
7. The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions.
Simón-Sánchez J; Dopper EG; Cohn-Hokke PE; Hukema RK; Nicolaou N; Seelaar H; de Graaf JR; de Koning I; van Schoor NM; Deeg DJ; Smits M; Raaphorst J; van den Berg LH; Schelhaas HJ; De Die-Smulders CE; Majoor-Krakauer D; Rozemuller AJ; Willemsen R; Pijnenburg YA; Heutink P; van Swieten JC
Brain; 2012 Mar; 135(Pt 3):723-35. PubMed ID: 22300876
[TBL] [Abstract][Full Text] [Related]
8. Solution structure of a DNA quadruplex containing ALS and FTD related GGGGCC repeat stabilized by 8-bromodeoxyguanosine substitution.
Brčić J; Plavec J
Nucleic Acids Res; 2015 Sep; 43(17):8590-600. PubMed ID: 26253741
[TBL] [Abstract][Full Text] [Related]
9. Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.
Wen X; Westergard T; Pasinelli P; Trotti D
Neurosci Lett; 2017 Jan; 636():16-26. PubMed ID: 27619540
[TBL] [Abstract][Full Text] [Related]
10. Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD.
Zhou B; Liu C; Geng Y; Zhu G
Sci Rep; 2015 Nov; 5():16673. PubMed ID: 26564809
[TBL] [Abstract][Full Text] [Related]
11. Characterization of DNA G-quadruplex species forming from C9ORF72 G4C2-expanded repeats associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Šket P; Pohleven J; Kovanda A; Štalekar M; Župunski V; Zalar M; Plavec J; Rogelj B
Neurobiol Aging; 2015 Feb; 36(2):1091-6. PubMed ID: 25442110
[TBL] [Abstract][Full Text] [Related]
12. Stress-induced acidification may contribute to formation of unusual structures in C9orf72-repeats.
Zamiri B; Mirceta M; Abu-Ghazalah R; Wold MS; Pearson CE; Macgregor RB
Biochim Biophys Acta Gen Subj; 2018 Jun; 1862(6):1482-1491. PubMed ID: 29550431
[TBL] [Abstract][Full Text] [Related]
13. Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS.
Su Z; Zhang Y; Gendron TF; Bauer PO; Chew J; Yang WY; Fostvedt E; Jansen-West K; Belzil VV; Desaro P; Johnston A; Overstreet K; Oh SY; Todd PK; Berry JD; Cudkowicz ME; Boeve BF; Dickson D; Floeter MK; Traynor BJ; Morelli C; Ratti A; Silani V; Rademakers R; Brown RH; Rothstein JD; Boylan KB; Petrucelli L; Disney MD
Neuron; 2014 Sep; 83(5):1043-50. PubMed ID: 25132468
[TBL] [Abstract][Full Text] [Related]
14. Structural and Dynamical Characterization of DNA and RNA Quadruplexes Obtained from the GGGGCC and GGGCCT Hexanucleotide Repeats Associated with C9FTD/ALS and SCA36 Diseases.
Zhang Y; Roland C; Sagui C
ACS Chem Neurosci; 2018 May; 9(5):1104-1117. PubMed ID: 29281254
[TBL] [Abstract][Full Text] [Related]
15. The Emerging Role of DNA Damage in the Pathogenesis of the C9orf72 Repeat Expansion in Amyotrophic Lateral Sclerosis.
Konopka A; Atkin JD
Int J Mol Sci; 2018 Oct; 19(10):. PubMed ID: 30322030
[TBL] [Abstract][Full Text] [Related]
16. Characterizations of distinct parallel and antiparallel G-quadruplexes formed by two-repeat ALS and FTD related GGGGCC sequence.
Zhou B; Geng Y; Liu C; Miao H; Ren Y; Xu N; Shi X; You Y; Lee T; Zhu G
Sci Rep; 2018 Feb; 8(1):2366. PubMed ID: 29402965
[TBL] [Abstract][Full Text] [Related]
17. ATNX2 is not a regulatory gene in Italian amyotrophic lateral sclerosis patients with C9ORF72 GGGGCC expansion.
Chiò A; Mora G; Sabatelli M; Caponnetto C; Lunetta C; Traynor BJ; Johnson JO; Nalls MA; Calvo A; Moglia C; Borghero G; Trojsi F; La Bella V; Volanti P; Simone I; Salvi F; Logullo FO; Riva N; Carrera P; Giannini F; Mandrioli J; Tanel R; Capasso M; Tremolizzo L; Battistini S; Murru MR; Origone P; Zollino M; Penco S; ; ; Mazzini L; D'Alfonso S; Restagno G; Brunetti M; Barberis M; Conforti FL
Neurobiol Aging; 2016 Mar; 39():218.e5-8. PubMed ID: 26733254
[TBL] [Abstract][Full Text] [Related]
18. Quadruplex formation by both G-rich and C-rich DNA strands of the C9orf72 (GGGGCC)8•(GGCCCC)8 repeat: effect of CpG methylation.
Zamiri B; Mirceta M; Bomsztyk K; Macgregor RB; Pearson CE
Nucleic Acids Res; 2015 Nov; 43(20):10055-64. PubMed ID: 26432832
[TBL] [Abstract][Full Text] [Related]
19. hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations.
Mori K; Lammich S; Mackenzie IR; Forné I; Zilow S; Kretzschmar H; Edbauer D; Janssens J; Kleinberger G; Cruts M; Herms J; Neumann M; Van Broeckhoven C; Arzberger T; Haass C
Acta Neuropathol; 2013 Mar; 125(3):413-23. PubMed ID: 23381195
[TBL] [Abstract][Full Text] [Related]
20. C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms.
Wang X; Goodrich KJ; Conlon EG; Gao J; Erbse AH; Manley JL; Cech TR
RNA; 2019 Aug; 25(8):935-947. PubMed ID: 31048495
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
