These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis. De Luca L; Ferro S; Buemi MR; Monforte AM; Gitto R; Schirmeister T; Maes L; Rescifina A; Micale N Chem Biol Drug Des; 2018 Sep; 92(3):1585-1596. PubMed ID: 29729080 [TBL] [Abstract][Full Text] [Related]
23. Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification. Braga SF; Martins LC; da Silva EB; Sales Júnior PA; Murta SM; Romanha AJ; Soh WT; Brandstetter H; Ferreira RS; de Oliveira RB Bioorg Med Chem; 2017 Mar; 25(6):1889-1900. PubMed ID: 28215783 [TBL] [Abstract][Full Text] [Related]
24. Assessment of leishmanicidal and trypanocidal activities of aliphatic diamine derivatives. Yamanaka CN; Giordani RB; Rezende CO; Eger I; Kessler RL; Tonini ML; de Moraes MH; Araújo DP; Zuanazzi JA; de Almeida MV; Steindel M Chem Biol Drug Des; 2013 Dec; 82(6):697-704. PubMed ID: 23865595 [TBL] [Abstract][Full Text] [Related]
25. Leishmania major: molecular modeling of cysteine proteases and prediction of new nonpeptide inhibitors. Selzer PM; Chen X; Chan VJ; Cheng M; Kenyon GL; Kuntz ID; Sakanari JA; Cohen FE; McKerrow JH Exp Parasitol; 1997 Nov; 87(3):212-21. PubMed ID: 9371086 [TBL] [Abstract][Full Text] [Related]
26. Development of alpha-keto-based inhibitors of cruzain, a cysteine protease implicated in Chagas disease. Choe Y; Brinen LS; Price MS; Engel JC; Lange M; Grisostomi C; Weston SG; Pallai PV; Cheng H; Hardy LW; Hartsough DS; McMakin M; Tilton RF; Baldino CM; Craik CS Bioorg Med Chem; 2005 Mar; 13(6):2141-56. PubMed ID: 15727867 [TBL] [Abstract][Full Text] [Related]
27. Mapping the S1 and S1' subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents. Cianni L; Lemke C; Gilberg E; Feldmann C; Rosini F; Rocho FDR; Ribeiro JFR; Tezuka DY; Lopes CD; de Albuquerque S; Bajorath J; Laufer S; Leitão A; Gütschow M; Montanari CA PLoS Negl Trop Dis; 2020 Mar; 14(3):e0007755. PubMed ID: 32163418 [TBL] [Abstract][Full Text] [Related]
28. The C-terminal extension of Leishmania pifanoi amastigote-specific cysteine proteinase Lpcys2: a putative function in macrophage infection. Marín-Villa M; Vargas-Inchaustegui DA; Chaves SP; Tempone AJ; Dutra JM; Soares MJ; Ueda-Nakamura T; Mendonça SC; Rossi-Bergmann B; Soong L; Traub-Csekö YM Mol Biochem Parasitol; 2008 Nov; 162(1):52-9. PubMed ID: 18694784 [TBL] [Abstract][Full Text] [Related]
29. Leishmanicidal, antiproteolytic and antioxidant evaluation of natural biflavonoids isolated from Garcinia brasiliensis and their semisynthetic derivatives. Gontijo VS; Judice WA; Codonho B; Pereira IO; Assis DM; Januário JP; Caroselli EE; Juliano MA; de Carvalho Dosatti A; Marques MJ; Viegas Junior C; Henrique dos Santos M Eur J Med Chem; 2012 Dec; 58():613-23. PubMed ID: 23178961 [TBL] [Abstract][Full Text] [Related]
30. Acid heteropolysaccharides with potent antileishmanial effects. Kangussu-Marcolino MM; do Rosário MM; Noseda MD; Duarte ME; Ducatti DR; Cassolato JE; Iacomini M; Martinez GR; Rocha ME; Cadena SM; Noleto GR Int J Biol Macromol; 2015 Nov; 81():165-70. PubMed ID: 26162246 [TBL] [Abstract][Full Text] [Related]
31. Natural products from Garcinia brasiliensis as Leishmania protease inhibitors. Pereira IO; Assis DM; Juliano MA; Cunha RL; Barbieri CL; do Sacramento LV; Marques MJ; dos Santos MH J Med Food; 2011 Jun; 14(6):557-62. PubMed ID: 21554130 [TBL] [Abstract][Full Text] [Related]
32. Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain. Huang L; Brinen LS; Ellman JA Bioorg Med Chem; 2003 Jan; 11(1):21-9. PubMed ID: 12467703 [TBL] [Abstract][Full Text] [Related]
33. New benzophenone-derived bisphosphonium salts as leishmanicidal leads targeting mitochondria through inhibition of respiratory complex II. Luque-Ortega JR; Reuther P; Rivas L; Dardonville C J Med Chem; 2010 Feb; 53(4):1788-98. PubMed ID: 20128602 [TBL] [Abstract][Full Text] [Related]
34. New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8. Fey P; Chartomatsidou R; Kiefer W; Mottram JC; Kersten C; Schirmeister T Eur J Med Chem; 2018 Aug; 156():587-597. PubMed ID: 30029081 [TBL] [Abstract][Full Text] [Related]
35. Synthesis, Biological Activity, and Mechanism of Action of 2-Pyrazyl and Pyridylhydrazone Derivatives, New Classes of Antileishmanial Agents. Coimbra ES; Antinarelli LMR; de A Crispi M; Nogueira TCM; Pinheiro AC; de Souza MVN ChemMedChem; 2018 Jul; 13(14):1387-1394. PubMed ID: 29790287 [TBL] [Abstract][Full Text] [Related]
36. Natural polyprenylated benzophenones inhibiting cysteine and serine proteases. Martins FT; Assis DM; Dos Santos MH; Camps I; Veloso MP; Juliano MA; Alves LC; Doriguetto AC Eur J Med Chem; 2009 Mar; 44(3):1230-9. PubMed ID: 18995931 [TBL] [Abstract][Full Text] [Related]
37. Proteinase activities during temperature-induced stage differentiation of species complexes of Leishmania. Leon LL; Temporal RM; Soares MJ; Grimaldi Júnior G Acta Trop; 1994 Apr; 56(4):289-98. PubMed ID: 8023752 [TBL] [Abstract][Full Text] [Related]
38. Development of a New Antileishmanial Aziridine-2,3-Dicarboxylate-Based Inhibitor with High Selectivity for Parasite Cysteine Proteases. Schad C; Baum U; Frank B; Dietzel U; Mattern F; Gomes C; Ponte-Sucre A; Moll H; Schurigt U; Schirmeister T Antimicrob Agents Chemother; 2016 Feb; 60(2):797-805. PubMed ID: 26596939 [TBL] [Abstract][Full Text] [Related]
39. High selective leishmanicidal activity of 3-hydroxy-2-methylene-3-(4-bromophenyl)propanenitrile and analogous compounds. de Souza RO; Pereira VL; Muzitano MF; Falcão CA; Rossi-Bergmann B; Filho EB; Vasconcellos ML Eur J Med Chem; 2007 Jan; 42(1):99-102. PubMed ID: 17010481 [TBL] [Abstract][Full Text] [Related]
40. Evaluation of the leishmanicidal and cytotoxic effects of inhibitors for microorganism metabolic pathway enzymes. de Mesquita Barbosa A; Dos Santos Costa S; da Rocha JR; Montanari CA; Giorgio S Biomed Pharmacother; 2015 Aug; 74():95-100. PubMed ID: 26349969 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]