190 related articles for article (PubMed ID: 26466958)
1. A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.
Cho HS; Shin HM; Haberstock-Debic H; Xing Y; Owens TD; Funk JO; Hill RJ; Bradshaw JM; Berg LJ
J Immunol; 2015 Nov; 195(10):4822-31. PubMed ID: 26466958
[TBL] [Abstract][Full Text] [Related]
2. Targeting interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) using a novel covalent inhibitor PRN694.
Zhong Y; Dong S; Strattan E; Ren L; Butchar JP; Thornton K; Mishra A; Porcu P; Bradshaw JM; Bisconte A; Owens TD; Verner E; Brameld KA; Funk JO; Hill RJ; Johnson AJ; Dubovsky JA
J Biol Chem; 2015 Mar; 290(10):5960-78. PubMed ID: 25593320
[TBL] [Abstract][Full Text] [Related]
3. Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.
Sahu N; Venegas AM; Jankovic D; Mitzner W; Gomez-Rodriguez J; Cannons JL; Sommers C; Love P; Sher A; Schwartzberg PL; August A
J Immunol; 2008 Nov; 181(9):6125-31. PubMed ID: 18941202
[TBL] [Abstract][Full Text] [Related]
4. Allele-sensitive mutant, Itkas, reveals that Itk kinase activity is required for Th1, Th2, Th17, and iNKT-cell cytokine production.
Kannan A; Lee Y; Qi Q; Huang W; Jeong AR; Ohnigian S; August A
Eur J Immunol; 2015 Aug; 45(8):2276-85. PubMed ID: 25989458
[TBL] [Abstract][Full Text] [Related]
5. The Tec kinases Itk and Rlk regulate NKT cell maturation, cytokine production, and survival.
Felices M; Berg LJ
J Immunol; 2008 Mar; 180(5):3007-18. PubMed ID: 18292523
[TBL] [Abstract][Full Text] [Related]
6. ITK and RLK Inhibitor PRN694 Improves Skin Disease in Two Mouse Models of Psoriasis.
Fuhriman JM; Winge MCG; Haberstock-Debic H; Funk JO; Bradshaw JM; Marinkovich MP
J Invest Dermatol; 2018 Apr; 138(4):864-871. PubMed ID: 29129599
[TBL] [Abstract][Full Text] [Related]
7. IL-2-inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells.
Kannan AK; Sahu N; Mohanan S; Mohinta S; August A
J Allergy Clin Immunol; 2013 Oct; 132(4):811-20.e1-5. PubMed ID: 23768572
[TBL] [Abstract][Full Text] [Related]
8. A negative role for the interleukin-2-inducible T-cell kinase (ITK) in human Foxp3+ TREG differentiation.
Mamontov P; Eberwine RA; Perrigoue J; Das A; Friedman JR; Mora JR
PLoS One; 2019; 14(4):e0215963. PubMed ID: 31022269
[TBL] [Abstract][Full Text] [Related]
9. Microbiota Metabolite Butyrate Differentially Regulates Th1 and Th17 Cells' Differentiation and Function in Induction of Colitis.
Chen L; Sun M; Wu W; Yang W; Huang X; Xiao Y; Ma C; Xu L; Yao S; Liu Z; Cong Y
Inflamm Bowel Dis; 2019 Aug; 25(9):1450-1461. PubMed ID: 30918945
[TBL] [Abstract][Full Text] [Related]
10. A key role for Itk in both IFN gamma and IL-4 production by NKT cells.
Au-Yeung BB; Fowell DJ
J Immunol; 2007 Jul; 179(1):111-9. PubMed ID: 17579028
[TBL] [Abstract][Full Text] [Related]
11. Mutation of Tec family kinases alters T helper cell differentiation.
Schaeffer EM; Yap GS; Lewis CM; Czar MJ; McVicar DW; Cheever AW; Sher A; Schwartzberg PL
Nat Immunol; 2001 Dec; 2(12):1183-8. PubMed ID: 11702066
[TBL] [Abstract][Full Text] [Related]
12. TGF-β converts Th1 cells into Th17 cells through stimulation of Runx1 expression.
Liu HP; Cao AT; Feng T; Li Q; Zhang W; Yao S; Dann SM; Elson CO; Cong Y
Eur J Immunol; 2015 Apr; 45(4):1010-8. PubMed ID: 25605286
[TBL] [Abstract][Full Text] [Related]
13. Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet.
Miller AT; Wilcox HM; Lai Z; Berg LJ
Immunity; 2004 Jul; 21(1):67-80. PubMed ID: 15345221
[TBL] [Abstract][Full Text] [Related]
14. Role of ITK signaling in acute kidney injury in mice: Amelioration of acute kidney injury associated clinical parameters and attenuation of inflammatory transcription factor signaling in CD4+ T cells by ITK inhibition.
Nadeem A; Ahmad SF; Al-Harbi NO; Ibrahim KE; Sarawi W; Attia SM; Alasmari AF; Alqarni SA; Alfradan AS; Bakheet SA; Al-Harbi MM
Int Immunopharmacol; 2021 Oct; 99():108028. PubMed ID: 34365077
[TBL] [Abstract][Full Text] [Related]
15. Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells.
Sujino T; Kanai T; Ono Y; Mikami Y; Hayashi A; Doi T; Matsuoka K; Hisamatsu T; Takaishi H; Ogata H; Yoshimura A; Littman DR; Hibi T
Gastroenterology; 2011 Sep; 141(3):1014-23. PubMed ID: 21699791
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.
Sun Y; Peng I; Webster JD; Suto E; Lesch J; Wu X; Senger K; Francis G; Barrett K; Collier JL; Burch JD; Zhou M; Chen Y; Chan C; Eastham-Anderson J; Ngu H; Li O; Staton T; Havnar C; Jaochico A; Jackman J; Jeet S; Riol-Blanco L; Wu LC; Choy DF; Arron JR; McKenzie BS; Ghilardi N; Ismaili MH; Pei Z; DeVoss J; Austin CD; Lee WP; Zarrin AA
Sci Signal; 2015 Dec; 8(405):ra122. PubMed ID: 26628680
[TBL] [Abstract][Full Text] [Related]
17. Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells.
Gomez-Rodriguez J; Wohlfert EA; Handon R; Meylan F; Wu JZ; Anderson SM; Kirby MR; Belkaid Y; Schwartzberg PL
J Exp Med; 2014 Mar; 211(3):529-43. PubMed ID: 24534190
[TBL] [Abstract][Full Text] [Related]
18. Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help.
Atherly LO; Brehm MA; Welsh RM; Berg LJ
J Immunol; 2006 Feb; 176(3):1571-81. PubMed ID: 16424186
[TBL] [Abstract][Full Text] [Related]
19. Immunoproteasome subunit LMP7 deficiency and inhibition suppresses Th1 and Th17 but enhances regulatory T cell differentiation.
Kalim KW; Basler M; Kirk CJ; Groettrup M
J Immunol; 2012 Oct; 189(8):4182-93. PubMed ID: 22984077
[TBL] [Abstract][Full Text] [Related]
20. Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.
Mikami Y; Kanai T; Sujino T; Ono Y; Hayashi A; Okazawa A; Kamada N; Matsuoka K; Hisamatsu T; Okamoto S; Takaishi H; Inoue N; Ogata H; Hibi T
Eur J Immunol; 2010 Sep; 40(9):2409-22. PubMed ID: 20706984
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
