These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 26467692)

  • 1. A rapid method for simultaneous evaluation of free light chain content and aggregate content in culture media of Chinese hamster ovary cells expressing monoclonal antibodies for cell line screening.
    Ishii Y; Tsukahara M; Wakamatsu K
    J Biosci Bioeng; 2016 Apr; 121(4):464-70. PubMed ID: 26467692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Free light chain content in culture media reflects recombinant monoclonal antibody productivity and quality.
    Bhoskar P; Belongia B; Smith R; Yoon S; Carter T; Xu J
    Biotechnol Prog; 2013; 29(5):1131-9. PubMed ID: 23798487
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficient folding/assembly in Chinese hamster ovary cells is critical for high quality (low aggregate content) of secreted trastuzumab as well as for high production: stepwise multivariate regression analyses.
    Ishii Y; Murakami J; Sasaki K; Tsukahara M; Wakamatsu K
    J Biosci Bioeng; 2014 Aug; 118(2):223-30. PubMed ID: 24635945
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells.
    Chng J; Wang T; Nian R; Lau A; Hoi KM; Ho SC; Gagnon P; Bi X; Yang Y
    MAbs; 2015; 7(2):403-12. PubMed ID: 25621616
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of hydrolysates on monoclonal antibody productivity, purification and quality in Chinese hamster ovary cells.
    Ho SC; Nian R; Woen S; Chng J; Zhang P; Yang Y
    J Biosci Bioeng; 2016 Oct; 122(4):499-506. PubMed ID: 27067279
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Direct analysis of mAb aggregates in mammalian cell culture supernatant.
    Paul AJ; Schwab K; Hesse F
    BMC Biotechnol; 2014 Nov; 14():99. PubMed ID: 25431119
    [TBL] [Abstract][Full Text] [Related]  

  • 7. On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.
    Schlatter S; Stansfield SH; Dinnis DM; Racher AJ; Birch JR; James DC
    Biotechnol Prog; 2005; 21(1):122-33. PubMed ID: 15903249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analytical characterization of a monoclonal antibody therapeutic reveals a three-light chain species that is efficiently removed using hydrophobic interaction chromatography.
    Wollacott RB; Casaz PL; Morin TJ; Zhu HL; Anderson RS; Babcock GJ; Que J; Thomas WD; Ozturk SS
    MAbs; 2013; 5(6):925-35. PubMed ID: 23995619
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of monoclonal antibody size variants containing extra light chains.
    Lu C; Liu D; Liu H; Motchnik P
    MAbs; 2013; 5(1):102-13. PubMed ID: 23255003
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Investigation of the free heavy chain homodimers of a monoclonal antibody.
    Chung HH; Buck L; Daris K; Welborn B; Luo Q; Wypych J
    Biotechnol Prog; 2018 May; 34(3):738-745. PubMed ID: 29341500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of antibody molecules produced from two cell lines with contrasting productivities and aggregate contents.
    Ishii Y; Imamoto Y; Yamamoto R; Tsukahara M; Wakamatsu K
    Biol Pharm Bull; 2015; 38(2):306-16. PubMed ID: 25501618
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Combined Protein A and size exclusion high performance liquid chromatography for the single-step measurement of mAb, aggregates and host cell proteins.
    Gjoka X; Schofield M; Cvetkovic A; Gantier R
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Dec; 972():48-52. PubMed ID: 25310707
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Using molecular markers to characterize productivity in Chinese hamster ovary cell lines.
    Edros RZ; McDonnell S; Al-Rubeai M
    PLoS One; 2013; 8(10):e75935. PubMed ID: 24146795
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Control of IgG LC:HC ratio in stably transfected CHO cells and study of the impact on expression, aggregation, glycosylation and conformational stability.
    Ho SC; Koh EY; van Beers M; Mueller M; Wan C; Teo G; Song Z; Tong YW; Bardor M; Yang Y
    J Biotechnol; 2013 Jun; 165(3-4):157-66. PubMed ID: 23583871
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optimization of cell line development in the GS-CHO expression system using a high-throughput, single cell-based clone selection system.
    Nakamura T; Omasa T
    J Biosci Bioeng; 2015 Sep; 120(3):323-9. PubMed ID: 25792187
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Catechins prevent monoclonal antibody fragmentation during production via fed-batch culture of Chinese hamster ovary cells.
    Yamaguchi T; Ishikawa H; Fukuda M; Sugita Y; Furuie M; Nagano R; Suzawa T; Yamamoto K; Wakamatsu K
    Biotechnol Prog; 2024; 40(3):e3447. PubMed ID: 38415979
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Capillary size exclusion chromatography with picogram sensitivity for analysis of monoclonal antibodies purified from harvested cell culture fluid.
    Rea JC; Moreno GT; Vampola L; Lou Y; van Haan B; Tremintin G; Simmons L; Nava A; Wang YJ; Farnan D
    J Chromatogr A; 2012 Jan; 1219():140-6. PubMed ID: 22153816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Titer of trastuzumab produced by a Chinese hamster ovary cell line is associated with tricarboxylic acid cycle activity rather than lactate metabolism.
    Ishii Y; Imamoto Y; Yamamoto R; Tsukahara M; Wakamatsu K
    J Biosci Bioeng; 2015 Apr; 119(4):478-85. PubMed ID: 25449760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development and manufacturability assessment of chemically-defined medium for the production of protein therapeutics in CHO cells.
    Ling WL; Bai Y; Cheng C; Padawer I; Wu C
    Biotechnol Prog; 2015; 31(5):1163-71. PubMed ID: 26013818
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fluorescence dye-based detection of mAb aggregates in CHO culture supernatants.
    Paul AJ; Schwab K; Prokoph N; Haas E; Handrick R; Hesse F
    Anal Bioanal Chem; 2015 Jun; 407(16):4849-56. PubMed ID: 25869484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.