BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 26469213)

  • 1. Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.
    Cinelli MA; Li H; Pensa AV; Kang S; Roman LJ; Martásek P; Poulos TL; Silverman RB
    J Med Chem; 2015 Nov; 58(21):8694-712. PubMed ID: 26469213
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.
    Pensa AV; Cinelli MA; Li H; Chreifi G; Mukherjee P; Roman LJ; Martásek P; Poulos TL; Silverman RB
    J Med Chem; 2017 Aug; 60(16):7146-7165. PubMed ID: 28776992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition.
    Cinelli MA; Li H; Chreifi G; Martásek P; Roman LJ; Poulos TL; Silverman RB
    J Med Chem; 2014 Feb; 57(4):1513-30. PubMed ID: 24472039
    [TBL] [Abstract][Full Text] [Related]  

  • 4. First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.
    Cinelli MA; Reidl CT; Li H; Chreifi G; Poulos TL; Silverman RB
    J Med Chem; 2020 May; 63(9):4528-4554. PubMed ID: 32302123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
    Cinelli MA; Li H; Chreifi G; Poulos TL; Silverman RB
    J Med Chem; 2017 May; 60(9):3958-3978. PubMed ID: 28422508
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.
    Hah JM; Martásek P; Roman LJ; Silverman RB
    J Med Chem; 2003 Apr; 46(9):1661-9. PubMed ID: 12699384
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.
    Jing Q; Li H; Chreifi G; Roman LJ; Martásek P; Poulos TL; Silverman RB
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5674-9. PubMed ID: 23993333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of a series of aminopiperidines as novel iNOS inhibitors.
    Le Bourdonnec B; Leister LK; Ajello CA; Cassel JA; Seida PR; O'Hare H; Gu M; Chu GH; Tuthill PA; DeHaven RN; Dolle RE
    Bioorg Med Chem Lett; 2008 Jan; 18(1):336-43. PubMed ID: 18024030
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.
    Do HT; Wang HY; Li H; Chreifi G; Poulos TL; Silverman RB
    J Med Chem; 2017 Nov; 60(22):9360-9375. PubMed ID: 29091437
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.
    Kang S; Tang W; Li H; Chreifi G; Martásek P; Roman LJ; Poulos TL; Silverman RB
    J Med Chem; 2014 May; 57(10):4382-96. PubMed ID: 24758147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
    López Cara LC; Camacho ME; Carrión MD; Tapias V; Gallo MA; Escames G; Acuña-Castroviejo D; Espinosa A; Entrena A
    Eur J Med Chem; 2009 Jun; 44(6):2655-66. PubMed ID: 19117642
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for dipeptide amide isoform-selective inhibition of neuronal nitric oxide synthase.
    Flinspach ML; Li H; Jamal J; Yang W; Huang H; Hah JM; Gómez-Vidal JA; Litzinger EA; Silverman RB; Poulos TL
    Nat Struct Mol Biol; 2004 Jan; 11(1):54-9. PubMed ID: 14718923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Screening of novel and selective inhibitors for neuronal nitric oxide synthase (nNOS) via structure-based drug design techniques.
    Boumezber S; Yelekçi K
    J Biomol Struct Dyn; 2023 May; 41(8):3607-3629. PubMed ID: 35322764
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Contribution of nitric oxide synthase isoforms to cholinergic vasodilation in murine retinal arterioles.
    Gericke A; Goloborodko E; Sniatecki JJ; Steege A; Wojnowski L; Pfeiffer N
    Exp Eye Res; 2013 Apr; 109():60-6. PubMed ID: 23434456
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.
    Wang HY; Qin Y; Li H; Roman LJ; Martásek P; Poulos TL; Silverman RB
    J Med Chem; 2016 May; 59(10):4913-25. PubMed ID: 27050842
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.
    Hah JM; Roman LJ; Martásek P; Silverman RB
    J Med Chem; 2001 Aug; 44(16):2667-70. PubMed ID: 11472219
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors.
    Chayah M; Carrión MD; Gallo MA; Jiménez R; Duarte J; Camacho ME
    ChemMedChem; 2015 May; 10(5):874-82. PubMed ID: 25801086
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.
    Ji H; Gómez-Vidal JA; Martasek P; Roman LJ; Silverman RB
    J Med Chem; 2006 Oct; 49(21):6254-63. PubMed ID: 17034131
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL; Shearer BG; Oplinger JA; Lee S; Garvey EP; Salter M; Duffy C; Burnette TC; Furfine ES
    J Med Chem; 1998 Jul; 41(15):2858-71. PubMed ID: 9667974
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Fire ant venom alkaloid, isosolenopsin A, a potent and selective inhibitor of neuronal nitric oxide synthase.
    Yi GB; McClendon D; Desaiah D; Goddard J; Lister A; Moffitt J; Meer RK; deShazo R; Lee KS; Rockhold RW
    Int J Toxicol; 2003; 22(2):81-6. PubMed ID: 12745988
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.