These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 26471247)

  • 1. Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.
    Nakano K; Chigira T; Miyafusa T; Nagatoishi S; Caaveiro JM; Tsumoto K
    Sci Rep; 2015 Oct; 5():15337. PubMed ID: 26471247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains.
    Miyafusa T; Caaveiro JM; Tanaka Y; Tsumoto K
    Biochem J; 2012 May; 443(3):671-80. PubMed ID: 22320426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
    Krucinska J; Falcone E; Erlandsen H; Hazeen A; Lombardo MN; Estrada A; Robinson VL; Anderson AC; Wright DL
    Biochemistry; 2019 Mar; 58(9):1188-1197. PubMed ID: 30714720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The basis for non-canonical ROK family function in the
    Coombes D; Davies JS; Newton-Vesty MC; Horne CR; Setty TG; Subramanian R; Moir JWB; Friemann R; Panjikar S; Griffin MDW; North RA; Dobson RCJ
    J Biol Chem; 2020 Mar; 295(10):3301-3315. PubMed ID: 31949045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antagonism of a zinc metalloprotease using a unique metal-chelating scaffold: tropolones as inhibitors of P. aeruginosa elastase.
    Fullagar JL; Garner AL; Struss AK; Day JA; Martin DP; Yu J; Cai X; Janda KD; Cohen SM
    Chem Commun (Camb); 2013 Apr; 49(31):3197-9. PubMed ID: 23482955
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
    Mesleh MF; Cross JB; Zhang J; Kahmann J; Andersen OA; Barker J; Cheng RK; Felicetti B; Wood M; Hadfield AT; Scheich C; Moy TI; Yang Q; Shotwell J; Nguyen K; Lippa B; Dolle R; Ryan MD
    Bioorg Med Chem Lett; 2016 Feb; 26(4):1314-8. PubMed ID: 26786695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Systematic analysis and integrative discovery of active-site subpocket-specific dehydroquinate synthase inhibitors combating antibiotic-resistant Staphylococcus aureus infection.
    Liu Q; Li L; Xu F
    J Bioinform Comput Biol; 2018 Dec; 16(6):1850027. PubMed ID: 30567475
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity.
    Oefner C; Bandera M; Haldimann A; Laue H; Schulz H; Mukhija S; Parisi S; Weiss L; Lociuro S; Dale GE
    J Antimicrob Chemother; 2009 Apr; 63(4):687-98. PubMed ID: 19211577
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
    Paparella AS; Lee KJ; Hayes AJ; Feng J; Feng Z; Cini D; Deshmukh S; Booker GW; Wilce MCJ; Polyak SW; Abell AD
    ACS Infect Dis; 2018 Feb; 4(2):175-184. PubMed ID: 29131575
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors.
    Lee SJ; Lee SJ; Lee SK; Yoon HJ; Lee HH; Kim KK; Lee BJ; Lee BI; Suh SW
    Acta Crystallogr D Biol Crystallogr; 2012 Jul; 68(Pt 7):784-93. PubMed ID: 22751663
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK).
    Martínez-Botella G; Loch JT; Green OM; Kawatkar SP; Olivier NB; Boriack-Sjodin PA; Keating TA
    Bioorg Med Chem Lett; 2013 Jan; 23(1):169-73. PubMed ID: 23206863
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mur ligases inhibitors with azastilbene scaffold: Expanding the structure-activity relationship.
    Hrast M; Frlan R; Knez D; Zdovc I; Barreteau H; Gobec S
    Bioorg Med Chem Lett; 2021 May; 40():127966. PubMed ID: 33744441
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular docking studies to map the binding site of squalene synthase inhibitors on dehydrosqualene synthase of Staphylococcus aureus.
    Kahlon AK; Roy S; Sharma A
    J Biomol Struct Dyn; 2010 Oct; 28(2):201-10. PubMed ID: 20645653
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of the Staphylococcus aureus capsule biosynthesis pathway in vitro: characterization of the UDP-GlcNAc C6 dehydratases CapD and CapE and identification of enzyme inhibitors.
    Li W; Ulm H; Rausch M; Li X; O'Riordan K; Lee JC; Schneider T; Müller CE
    Int J Med Microbiol; 2014 Nov; 304(8):958-69. PubMed ID: 25023075
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression, purification, crystallization and preliminary diffraction analysis of CapF, a capsular polysaccharide-synthesis enzyme from Staphylococcus aureus.
    Miyafusa T; Tanaka Y; Kuroda M; Ohta T; Tsumoto K
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Jun; 64(Pt 6):512-5. PubMed ID: 18540063
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and antimicrobial activities of thiouracil derivatives containing triazolo-thiadiazole as SecA inhibitors.
    Cui P; Li X; Zhu M; Wang B; Liu J; Chen H
    Eur J Med Chem; 2017 Feb; 127():159-165. PubMed ID: 28039774
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.
    Manchester JI; Dussault DD; Rose JA; Boriack-Sjodin PA; Uria-Nickelsen M; Ioannidis G; Bist S; Fleming P; Hull KG
    Bioorg Med Chem Lett; 2012 Aug; 22(15):5150-6. PubMed ID: 22814212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined pharmacophore and 3D-QSAR study on a series of Staphylococcus aureus Sortase A inhibitors.
    Uddin R; Lodhi MU; Ul-Haq Z
    Chem Biol Drug Des; 2012 Aug; 80(2):300-14. PubMed ID: 22553957
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and Biochemical Analyses Reveal that Chlorogenic Acid Inhibits the Shikimate Pathway.
    Neetu N; Katiki M; Dev A; Gaur S; Tomar S; Kumar P
    J Bacteriol; 2020 Aug; 202(18):. PubMed ID: 32661075
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The selectivity of galardin and an azasugar-based hydroxamate compound for human matrix metalloproteases and bacterial metalloproteases.
    Sylte I; Dawadi R; Malla N; von Hofsten S; Nguyen TM; Solli AI; Berg E; Adekoya OA; Svineng G; Winberg JO
    PLoS One; 2018; 13(8):e0200237. PubMed ID: 30075004
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.