BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 26472023)

  • 1. Mitotic entry: Non-genetic heterogeneity exposes the requirement for Plk1.
    Aspinall CF; Zheleva D; Tighe A; Taylor SS
    Oncotarget; 2015 Nov; 6(34):36472-88. PubMed ID: 26472023
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells.
    Choi M; Kim W; Cheon MG; Lee CW; Kim JE
    Cancer Lett; 2015 Feb; 357(2):591-601. PubMed ID: 25524551
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preferential Killing of Tetraploid Colon Cancer Cells by Targeting the Mitotic Kinase PLK1.
    Jemaà M; Kifagi C; Serrano SS; Massoumi R
    Cell Physiol Biochem; 2020 Apr; 54(2):303-320. PubMed ID: 32259417
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
    Lénárt P; Petronczki M; Steegmaier M; Di Fiore B; Lipp JJ; Hoffmann M; Rettig WJ; Kraut N; Peters JM
    Curr Biol; 2007 Feb; 17(4):304-15. PubMed ID: 17291761
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic polo-like kinase 1 inhibition results in mitotic arrest and subsequent cell death of blasts in the bone marrow of AML patients and has similar effects in non-neoplastic cell lines.
    Münch C; Dragoi D; Frey AV; Thurig K; Lübbert M; Wäsch R; Bogatyreva L; Hauschke D; Lassmann S; Werner M; May AM
    Leuk Res; 2015 Apr; 39(4):462-70. PubMed ID: 25697066
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential Cellular Effects of Plk1 Inhibitors Targeting the ATP-binding Domain or Polo-box Domain.
    Shin SB; Woo SU; Yim H
    J Cell Physiol; 2015 Dec; 230(12):3057-67. PubMed ID: 25975351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of polo-like kinase 1 leads to the suppression of osteosarcoma cell growth in vitro and in vivo.
    Liu X; Choy E; Harmon D; Yang S; Yang C; Mankin H; Hornicek FJ; Duan Z
    Anticancer Drugs; 2011 Jun; 22(5):444-53. PubMed ID: 21399492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines.
    Driscoll DL; Chakravarty A; Bowman D; Shinde V; Lasky K; Shi J; Vos T; Stringer B; Amidon B; D'Amore N; Hyer ML
    PLoS One; 2014; 9(11):e111060. PubMed ID: 25365521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Plk1 induces mitotic infidelity and embryonic growth defects in developing zebrafish embryos.
    Jeong K; Jeong JY; Lee HO; Choi E; Lee H
    Dev Biol; 2010 Sep; 345(1):34-48. PubMed ID: 20553902
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Co-inhibition of polo-like kinase 1 and Aurora kinases promotes mitotic catastrophe.
    Li J; Hong MJ; Chow JP; Man WY; Mak JP; Ma HT; Poon RY
    Oncotarget; 2015 Apr; 6(11):9327-40. PubMed ID: 25871386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polo-like kinase 1 is essential for the first mitotic division in the mouse embryo.
    Baran V; Solc P; Kovarikova V; Rehak P; Sutovsky P
    Mol Reprod Dev; 2013 Jul; 80(7):522-34. PubMed ID: 23649868
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis.
    Santamaria A; Neef R; Eberspächer U; Eis K; Husemann M; Mumberg D; Prechtl S; Schulze V; Siemeister G; Wortmann L; Barr FA; Nigg EA
    Mol Biol Cell; 2007 Oct; 18(10):4024-36. PubMed ID: 17671160
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impact of Polo-like kinase 1 inhibitors on human adipose tissue-derived mesenchymal stem cells.
    Ritter A; Friemel A; Kreis NN; Louwen F; Yuan J
    Oncotarget; 2016 Dec; 7(51):84271-84285. PubMed ID: 27713178
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.
    Smith L; Farzan R; Ali S; Buluwela L; Saurin AT; Meek DW
    Sci Rep; 2017 Nov; 7(1):16115. PubMed ID: 29170437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stathmin and microtubules regulate mitotic entry in HeLa cells by controlling activation of both Aurora kinase A and Plk1.
    Silva VC; Cassimeris L
    Mol Biol Cell; 2013 Dec; 24(24):3819-31. PubMed ID: 24152729
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PLK1 inhibitors: setting the mitotic death trap.
    Plyte S; Musacchio A
    Curr Biol; 2007 Apr; 17(8):R280-3. PubMed ID: 17437704
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Designed inhibitor for nuclear localization signal of polo-like kinase 1 induces mitotic arrest.
    Chen F; Zhuo X; Qin T; Guo X; Zhang C; Lai L
    Chem Biol Drug Des; 2017 May; 89(5):732-740. PubMed ID: 27882722
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optimized Plk1 PBD Inhibitors Based on Poloxin Induce Mitotic Arrest and Apoptosis in Tumor Cells.
    Scharow A; Raab M; Saxena K; Sreeramulu S; Kudlinzki D; Gande S; Dötsch C; Kurunci-Csacsko E; Klaeger S; Kuster B; Schwalbe H; Strebhardt K; Berg T
    ACS Chem Biol; 2015 Nov; 10(11):2570-9. PubMed ID: 26279064
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.
    Jang YJ; Ji JH; Choi YC; Ryu CJ; Ko SY
    J Biol Chem; 2007 Jan; 282(4):2473-82. PubMed ID: 17121863
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted inhibition of Polo-like kinase 1 by a novel small-molecule inhibitor induces mitotic catastrophe and apoptosis in human bladder cancer cells.
    Zhang Z; Zhang G; Kong C
    J Cell Mol Med; 2017 Apr; 21(4):758-767. PubMed ID: 27878946
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.