605 related articles for article (PubMed ID: 26472914)
1. Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2.
Jiao L; Liu X
Science; 2015 Oct; 350(6258):aac4383. PubMed ID: 26472914
[TBL] [Abstract][Full Text] [Related]
2. Structural analysis of an active fungal PRC2.
Jiao L; Liu X
Nucleus; 2016 May; 7(3):284-91. PubMed ID: 27187637
[TBL] [Abstract][Full Text] [Related]
3. Polycomb repressive complex 2 in an autoinhibited state.
Bratkowski M; Yang X; Liu X
J Biol Chem; 2017 Aug; 292(32):13323-13332. PubMed ID: 28607149
[TBL] [Abstract][Full Text] [Related]
4. Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Justin N; Zhang Y; Tarricone C; Martin SR; Chen S; Underwood E; De Marco V; Haire LF; Walker PA; Reinberg D; Wilson JR; Gamblin SJ
Nat Commun; 2016 Apr; 7():11316. PubMed ID: 27121947
[TBL] [Abstract][Full Text] [Related]
5. Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Zhang Y; Justin N; Wilson JR; Gamblin SJ
Science; 2016 Dec; 354(6319):1543. PubMed ID: 28008037
[TBL] [Abstract][Full Text] [Related]
6. Response to Comment on "Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2".
Jiao L; Liu X
Science; 2016 Dec; 354(6319):1543. PubMed ID: 28008038
[TBL] [Abstract][Full Text] [Related]
7. Structure of the catalytic domain of EZH2 reveals conformational plasticity in cofactor and substrate binding sites and explains oncogenic mutations.
Wu H; Zeng H; Dong A; Li F; He H; Senisterra G; Seitova A; Duan S; Brown PJ; Vedadi M; Arrowsmith CH; Schapira M
PLoS One; 2013; 8(12):e83737. PubMed ID: 24367611
[TBL] [Abstract][Full Text] [Related]
8. Embryonic Ectoderm Development (EED) as a Novel Target for Cancer Treatment.
Cook N; Chen J; Zhou J; Wu D
Curr Top Med Chem; 2021; 21(31):2771-2777. PubMed ID: 34544341
[TBL] [Abstract][Full Text] [Related]
9. An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Qi W; Zhao K; Gu J; Huang Y; Wang Y; Zhang H; Zhang M; Zhang J; Yu Z; Li L; Teng L; Chuai S; Zhang C; Zhao M; Chan H; Chen Z; Fang D; Fei Q; Feng L; Feng L; Gao Y; Ge H; Ge X; Li G; Lingel A; Lin Y; Liu Y; Luo F; Shi M; Wang L; Wang Z; Yu Y; Zeng J; Zeng C; Zhang L; Zhang Q; Zhou S; Oyang C; Atadja P; Li E
Nat Chem Biol; 2017 Apr; 13(4):381-388. PubMed ID: 28135235
[TBL] [Abstract][Full Text] [Related]
10. Structural context of disease-associated mutations and putative mechanism of autoinhibition revealed by X-ray crystallographic analysis of the EZH2-SET domain.
Antonysamy S; Condon B; Druzina Z; Bonanno JB; Gheyi T; Zhang F; MacEwan I; Zhang A; Ashok S; Rodgers L; Russell M; Gately Luz J
PLoS One; 2013; 8(12):e84147. PubMed ID: 24367637
[TBL] [Abstract][Full Text] [Related]
11. Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma.
Lee CH; Yu JR; Granat J; Saldaña-Meyer R; Andrade J; LeRoy G; Jin Y; Lund P; Stafford JM; Garcia BA; Ueberheide B; Reinberg D
Genes Dev; 2019 Oct; 33(19-20):1428-1440. PubMed ID: 31488577
[TBL] [Abstract][Full Text] [Related]
12. EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation.
Mu W; Starmer J; Yee D; Magnuson T
Epigenetics Chromatin; 2018 Dec; 11(1):71. PubMed ID: 30522506
[TBL] [Abstract][Full Text] [Related]
13. Role of the polycomb protein EED in the propagation of repressive histone marks.
Margueron R; Justin N; Ohno K; Sharpe ML; Son J; Drury WJ; Voigt P; Martin SR; Taylor WR; De Marco V; Pirrotta V; Reinberg D; Gamblin SJ
Nature; 2009 Oct; 461(7265):762-7. PubMed ID: 19767730
[TBL] [Abstract][Full Text] [Related]
14. Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2.
Kong X; Chen L; Jiao L; Jiang X; Lian F; Lu J; Zhu K; Du D; Liu J; Ding H; Zhang N; Shen J; Zheng M; Chen K; Liu X; Jiang H; Luo C
J Med Chem; 2014 Nov; 57(22):9512-21. PubMed ID: 25369470
[TBL] [Abstract][Full Text] [Related]
15. Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSET.
Swalm BM; Hallenbeck KK; Majer CR; Jin L; Scott MP; Moyer MP; Copeland RA; Wigle TJ
Biochem J; 2013 Jul; 453(2):241-7. PubMed ID: 23679895
[TBL] [Abstract][Full Text] [Related]
16. Ezh1 and Ezh2 differentially regulate PSD-95 gene transcription in developing hippocampal neurons.
Henriquez B; Bustos FJ; Aguilar R; Becerra A; Simon F; Montecino M; van Zundert B
Mol Cell Neurosci; 2013 Nov; 57():130-43. PubMed ID: 23932971
[TBL] [Abstract][Full Text] [Related]
17. The role of the polycomb repressive complex pathway in T and NK cell lymphoma: biological and prognostic implications.
Kim SH; Yang WI; Min YH; Ko YH; Yoon SO
Tumour Biol; 2016 Feb; 37(2):2037-47. PubMed ID: 26337274
[TBL] [Abstract][Full Text] [Related]
18. A Structural Perspective on Gene Repression by Polycomb Repressive Complex 2.
Liu X
Subcell Biochem; 2021; 96():519-562. PubMed ID: 33252743
[TBL] [Abstract][Full Text] [Related]
19. Structure, mechanism, and regulation of polycomb-repressive complex 2.
Moritz LE; Trievel RC
J Biol Chem; 2018 Sep; 293(36):13805-13814. PubMed ID: 28912274
[TBL] [Abstract][Full Text] [Related]
20. Global histone H3 lysine 27 triple methylation levels are reduced in vessels with advanced atherosclerotic plaques.
Wierda RJ; Rietveld IM; van Eggermond MC; Belien JA; van Zwet EW; Lindeman JH; van den Elsen PJ
Life Sci; 2015 May; 129():3-9. PubMed ID: 25445221
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
