These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

609 related articles for article (PubMed ID: 26472914)

  • 21. STRUCTURAL BIOLOGY. Chromatin complex, crystal clear.
    Schapira M
    Science; 2015 Oct; 350(6258):278-9. PubMed ID: 26472895
    [No Abstract]   [Full Text] [Related]  

  • 22. Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
    Xu C; Bian C; Yang W; Galka M; Ouyang H; Chen C; Qiu W; Liu H; Jones AE; MacKenzie F; Pan P; Li SS; Wang H; Min J
    Proc Natl Acad Sci U S A; 2010 Nov; 107(45):19266-71. PubMed ID: 20974918
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Non-core Subunits of the PRC2 Complex Are Collectively Required for Its Target-Site Specificity.
    Højfeldt JW; Hedehus L; Laugesen A; Tatar T; Wiehle L; Helin K
    Mol Cell; 2019 Nov; 76(3):423-436.e3. PubMed ID: 31521506
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.
    Brooun A; Gajiwala KS; Deng YL; Liu W; Bolaños B; Bingham P; He YA; Diehl W; Grable N; Kung PP; Sutton S; Maegley KA; Yu X; Stewart AE
    Nat Commun; 2016 Apr; 7():11384. PubMed ID: 27122193
    [TBL] [Abstract][Full Text] [Related]  

  • 25. An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors.
    Bratkowski M; Yang X; Liu X
    Sci Rep; 2018 Jun; 8(1):9092. PubMed ID: 29904056
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity.
    Ferrari KJ; Scelfo A; Jammula S; Cuomo A; Barozzi I; Stützer A; Fischle W; Bonaldi T; Pasini D
    Mol Cell; 2014 Jan; 53(1):49-62. PubMed ID: 24289921
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin.
    Chen S; Jiao L; Liu X; Yang X; Liu X
    Mol Cell; 2020 Mar; 77(6):1265-1278.e7. PubMed ID: 31959557
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations.
    Zhu K; Du D; Yang R; Tao H; Zhang H
    Chem Pharm Bull (Tokyo); 2020 Jan; 68(1):58-63. PubMed ID: 31685780
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2.
    Barnash KD; The J; Norris-Drouin JL; Cholensky SH; Worley BM; Li F; Stuckey JI; Brown PJ; Vedadi M; Arrowsmith CH; Frye SV; James LI
    ACS Comb Sci; 2017 Mar; 19(3):161-172. PubMed ID: 28165227
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Regulation of Retinal Development via the Epigenetic Modification of Histone H3.
    Watanabe S; Murakami A
    Adv Exp Med Biol; 2016; 854():635-41. PubMed ID: 26427469
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Propagation of trimethylated H3K27 regulated by polycomb protein EED is required for embryogenesis, hematopoietic maintenance, and tumor suppression.
    Ueda T; Nakata Y; Nagamachi A; Yamasaki N; Kanai A; Sera Y; Sasaki M; Matsui H; Honda Z; Oda H; Wolff L; Inaba T; Honda H
    Proc Natl Acad Sci U S A; 2016 Sep; 113(37):10370-5. PubMed ID: 27578866
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Discovery of selective activators of PRC2 mutant EED-I363M.
    Suh JL; Barnash KD; Abramyan TM; Li F; The J; Engelberg IA; Vedadi M; Brown PJ; Kireev DB; Arrowsmith CH; James LI; Frye SV
    Sci Rep; 2019 Apr; 9(1):6524. PubMed ID: 31024026
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Allosteric Inactivation of Polycomb Repressive Complex 2 (PRC2) by Inhibiting Its Adapter Protein: Embryonic Ectodomain Development (EED).
    Yang CY; Wang S
    J Med Chem; 2017 Mar; 60(6):2212-2214. PubMed ID: 28256832
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns.
    Zhou Y; Du DH; Wang J; Cai XQ; Deng AX; Nosjean O; Boutin JA; Renard P; Yang DH; Luo C; Wang MW
    Chem Biol Drug Des; 2020 Oct; 96(4):1024-1051. PubMed ID: 32394628
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3.
    Qin S; Guo Y; Xu C; Bian C; Fu M; Gong S; Min J
    Biochem Biophys Res Commun; 2013 Jan; 430(2):547-53. PubMed ID: 23228662
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding.
    Kasinath V; Poepsel S; Nogales E
    Biochemistry; 2019 Feb; 58(5):346-354. PubMed ID: 30451485
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation.
    Yuan W; Wu T; Fu H; Dai C; Wu H; Liu N; Li X; Xu M; Zhang Z; Niu T; Han Z; Chai J; Zhou XJ; Gao S; Zhu B
    Science; 2012 Aug; 337(6097):971-5. PubMed ID: 22923582
    [TBL] [Abstract][Full Text] [Related]  

  • 38. C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels.
    Shi Y; Ma HL; Zhuang YW; Wang XX; Jiang Y; Xu HE
    Acta Pharmacol Sin; 2019 Nov; 40(11):1457-1465. PubMed ID: 31186533
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Polycomb recruitment at the Class II transactivator gene.
    Boyd NH; Morgan JE; Greer SF
    Mol Immunol; 2015 Oct; 67(2 Pt B):482-91. PubMed ID: 26283540
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Reaction coupling between wild-type and disease-associated mutant EZH2.
    Swalm BM; Knutson SK; Warholic NM; Jin L; Kuntz KW; Keilhack H; Smith JJ; Pollock RM; Moyer MP; Scott MP; Copeland RA; Wigle TJ
    ACS Chem Biol; 2014 Nov; 9(11):2459-64. PubMed ID: 25154026
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 31.