These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 26475863)

  • 1. Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer.
    LoPiccolo J; Kim SJ; Shi Y; Wu B; Wu H; Chait BT; Singer RH; Sali A; Brenowitz M; Bresnick AR; Backer JM
    J Biol Chem; 2015 Dec; 290(51):30390-405. PubMed ID: 26475863
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of the PI3K pathway through a p85α monomer-homodimer equilibrium.
    Cheung LW; Walkiewicz KW; Besong TM; Guo H; Hawke DH; Arold ST; Mills GB
    Elife; 2015 Jul; 4():e06866. PubMed ID: 26222500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases.
    Hon WC; Berndt A; Williams RL
    Oncogene; 2012 Aug; 31(32):3655-66. PubMed ID: 22120714
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of PI3K/Akt signaling by n-terminal SH2 domain mutants of the p85α regulatory subunit of PI3K is enhanced by deletion of its c-terminal SH2 domain.
    Hofmann BT; Jücker M
    Cell Signal; 2012 Oct; 24(10):1950-4. PubMed ID: 22735814
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking.
    Mellor P; Furber LA; Nyarko JN; Anderson DH
    Biochem J; 2012 Jan; 441(1):23-37. PubMed ID: 22168437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impact of p85α Alterations in Cancer.
    Marshall JDS; Whitecross DE; Mellor P; Anderson DH
    Biomolecules; 2019 Jan; 9(1):. PubMed ID: 30650664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defining How Oncogenic and Developmental Mutations of PIK3R1 Alter the Regulation of Class IA Phosphoinositide 3-Kinases.
    Dornan GL; Stariha JTB; Rathinaswamy MK; Powell CJ; Boulanger MJ; Burke JE
    Structure; 2020 Feb; 28(2):145-156.e5. PubMed ID: 31831213
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α.
    Burke JE; Vadas O; Berndt A; Finegan T; Perisic O; Williams RL
    Structure; 2011 Aug; 19(8):1127-37. PubMed ID: 21827948
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases.
    Dornan GL; Burke JE
    Front Immunol; 2018; 9():575. PubMed ID: 29616047
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation.
    Xie Q; Guo X; Gu J; Zhang L; Jin H; Huang H; Li J; Huang C
    Oncotarget; 2016 Mar; 7(13):16636-49. PubMed ID: 26918608
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning, expression, purification, and characterization of the human Class Ia phosphoinositide 3-kinase isoforms.
    Meier TI; Cook JA; Thomas JE; Radding JA; Horn C; Lingaraj T; Smith MC
    Protein Expr Purif; 2004 Jun; 35(2):218-24. PubMed ID: 15135396
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cryo-EM structures of PI3Kα reveal conformational changes during inhibition and activation.
    Liu X; Yang S; Hart JR; Xu Y; Zou X; Zhang H; Zhou Q; Xia T; Zhang Y; Yang D; Wang MW; Vogt PK
    Proc Natl Acad Sci U S A; 2021 Nov; 118(45):. PubMed ID: 34725156
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase model.
    Oliver MD; Fernández-Acero T; Luna S; Rodríguez-Escudero I; Molina M; Pulido R; Cid VJ
    Biosci Rep; 2017 Apr; 37(2):. PubMed ID: 28143957
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The SH3 and BH domains of the p85alpha adapter subunit play a critical role in regulating class Ia phosphoinositide 3-kinase function.
    Beeton CA; Das P; Waterfield MD; Shepherd PR
    Mol Cell Biol Res Commun; 1999 May; 1(2):153-7. PubMed ID: 10356365
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nanobodies and chemical cross-links advance the structural and functional analysis of PI3Kα.
    Hart JR; Liu X; Pan C; Liang A; Ueno L; Xu Y; Quezada A; Zou X; Yang S; Zhou Q; Schoonooghe S; Hassanzadeh-Ghassabeh G; Xia T; Shui W; Yang D; Vogt PK; Wang MW
    Proc Natl Acad Sci U S A; 2022 Sep; 119(38):e2210769119. PubMed ID: 36095215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3-kinase (PI3K), p85α and p85β.
    Ito Y; Vogt PK; Hart JR
    Oncotarget; 2017 Aug; 8(34):55863-55876. PubMed ID: 28915558
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Class I PI3K-mediated Akt and ERK signals play a critical role in FcεRI-induced degranulation in mast cells.
    Takayama G; Ohtani M; Minowa A; Matsuda S; Koyasu S
    Int Immunol; 2013 Apr; 25(4):215-20. PubMed ID: 23143475
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p85α mediates NFAT3-dependent VEGF induction in the cellular UVB response.
    Dong W; Li Y; Li X; Hu M; Aodengqimuge ; Sun L; Guo N; Yuan S; Song L
    J Cell Sci; 2013 Mar; 126(Pt 6):1317-22. PubMed ID: 23390317
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Posttranscriptional regulation of the p85α adapter subunit of phosphatidylinositol 3-kinase in human leukemia cells.
    Hofmann BT; Hoxha E; Mohr E; Schulz K; Jücker M
    Leuk Lymphoma; 2011 Mar; 52(3):467-77. PubMed ID: 21077741
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of phospho-p85α-GTP-Rac1 lipid raft interaction by bichalcone analog attenuates cancer cell invasion.
    Lu HL; Chen SS; Hsu WT; Lu YC; Lee CC; Wu TS; Lin ML
    Mol Carcinog; 2016 Dec; 55(12):2106-2120. PubMed ID: 26756739
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.