373 related articles for article (PubMed ID: 26479318)
1. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Lin R; Elf S; Shan C; Kang HB; Ji Q; Zhou L; Hitosugi T; Zhang L; Zhang S; Seo JH; Xie J; Tucker M; Gu TL; Sudderth J; Jiang L; Mitsche M; DeBerardinis RJ; Wu S; Li Y; Mao H; Chen PR; Wang D; Chen GZ; Hurwitz SJ; Lonial S; Arellano ML; Khoury HJ; Khuri FR; Lee BH; Lei Q; Brat DJ; Ye K; Boggon TJ; He C; Kang S; Fan J; Chen J
Nat Cell Biol; 2015 Nov; 17(11):1484-96. PubMed ID: 26479318
[TBL] [Abstract][Full Text] [Related]
2. γ-6-Phosphogluconolactone, a Byproduct of the Oxidative Pentose Phosphate Pathway, Contributes to AMPK Activation through Inhibition of PP2A.
Gao X; Zhao L; Liu S; Li Y; Xia S; Chen D; Wang M; Wu S; Dai Q; Vu H; Zacharias L; DeBerardinis R; Lim E; Metallo C; Boggon TJ; Lonial S; Lin R; Mao H; Pan Y; Shan C; Chen J
Mol Cell; 2019 Dec; 76(6):857-871.e9. PubMed ID: 31586547
[TBL] [Abstract][Full Text] [Related]
3. Inhibiting 6-phosphogluconate dehydrogenase enhances chemotherapy efficacy in cervical cancer via AMPK-independent inhibition of RhoA and Rac1.
Guo H; Xiang Z; Zhang Y; Sun D
Clin Transl Oncol; 2019 Apr; 21(4):404-411. PubMed ID: 30182212
[TBL] [Abstract][Full Text] [Related]
4. 6PGD inhibition sensitizes hepatocellular carcinoma to chemotherapy via AMPK activation and metabolic reprogramming.
Chen H; Wu D; Bao L; Yin T; Lei D; Yu J; Tong X
Biomed Pharmacother; 2019 Mar; 111():1353-1358. PubMed ID: 30841449
[TBL] [Abstract][Full Text] [Related]
5. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.
Sukhatme VP; Chan B
FEBS Lett; 2012 Jul; 586(16):2389-95. PubMed ID: 22677172
[TBL] [Abstract][Full Text] [Related]
6. Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation.
Yang X; Peng X; Huang J
Clin Transl Oncol; 2018 Sep; 20(9):1145-1152. PubMed ID: 29340974
[TBL] [Abstract][Full Text] [Related]
7. A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth.
Gillis JL; Hinneh JA; Ryan NK; Irani S; Moldovan M; Quek LE; Shrestha RK; Hanson AR; Xie J; Hoy AJ; Holst J; Centenera MM; Mills IG; Lynn DJ; Selth LA; Butler LM
Elife; 2021 Aug; 10():. PubMed ID: 34382934
[TBL] [Abstract][Full Text] [Related]
8. 6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming.
Cao J; Sun X; Zhang X; Chen D
Am J Med Sci; 2020 Sep; 360(3):279-286. PubMed ID: 32829780
[TBL] [Abstract][Full Text] [Related]
9. 4-hydroxyphenylpyruvate dioxygenase promotes lung cancer growth via pentose phosphate pathway (PPP) flux mediated by LKB1-AMPK/HDAC10/G6PD axis.
Shan C; Lu Z; Li Z; Sheng H; Fan J; Qi Q; Liu S; Zhang S
Cell Death Dis; 2019 Jul; 10(7):525. PubMed ID: 31285420
[TBL] [Abstract][Full Text] [Related]
10. Gambogic acid exhibits promising anticancer activity by inhibiting the pentose phosphate pathway in lung cancer mouse model.
Zhang Q; Zhang Y; Wang C; Tang H; Ma A; Gao P; Shi Q; Wang G; Shen S; Zhang J; Xia F; Zhu Y; Wang J
Phytomedicine; 2024 Jul; 129():155657. PubMed ID: 38692076
[TBL] [Abstract][Full Text] [Related]
11. Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance.
Liu R; Li W; Tao B; Wang X; Yang Z; Zhang Y; Wang C; Liu R; Gao H; Liang J; Yang W
Nat Commun; 2019 Mar; 10(1):991. PubMed ID: 30824700
[TBL] [Abstract][Full Text] [Related]
12. 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met.
Chan B; VanderLaan PA; Sukhatme VP
Biochem Biophys Res Commun; 2013 Sep; 439(2):247-51. PubMed ID: 23973484
[TBL] [Abstract][Full Text] [Related]
13. Critical Role of 6-Phosphogluconate Dehydrogenase in TAp73-Mediated Cancer Cell Proliferation.
Qiao R; Wei M; Chen H; Zhang X; Zhang J; Gao L; Ma H; Wang Y; Li L
Mol Cancer Res; 2023 Aug; 21(8):825-835. PubMed ID: 37071129
[TBL] [Abstract][Full Text] [Related]
14. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.
Elf S; Lin R; Xia S; Pan Y; Shan C; Wu S; Lonial S; Gaddh M; Arellano ML; Khoury HJ; Khuri FR; Lee BH; Boggon TJ; Fan J; Chen J
Oncogene; 2017 Jan; 36(2):254-262. PubMed ID: 27270429
[TBL] [Abstract][Full Text] [Related]
15. 6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance.
Sarfraz I; Rasul A; Hussain G; Shah MA; Zahoor AF; Asrar M; Selamoglu Z; Ji XY; Adem Ş; Sarker SD
Biofactors; 2020 Jul; 46(4):550-562. PubMed ID: 32039535
[TBL] [Abstract][Full Text] [Related]
16. AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress.
Jeon SM; Chandel NS; Hay N
Nature; 2012 May; 485(7400):661-5. PubMed ID: 22660331
[TBL] [Abstract][Full Text] [Related]
17. Evidence for a direct cross-talk between malic enzyme and the pentose phosphate pathway via structural interactions.
Yao P; Sun H; Xu C; Chen T; Zou B; Jiang P; Du W
J Biol Chem; 2017 Oct; 292(41):17113-17120. PubMed ID: 28848047
[TBL] [Abstract][Full Text] [Related]
18. Blockade of 6-phosphogluconate dehydrogenase generates CD8
Daneshmandi S; Cassel T; Lin P; Higashi RM; Wulf GM; Boussiotis VA; Fan TW; Seth P
Cell Rep; 2021 Mar; 34(10):108831. PubMed ID: 33691103
[TBL] [Abstract][Full Text] [Related]
19. Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.
Shan C; Elf S; Ji Q; Kang HB; Zhou L; Hitosugi T; Jin L; Lin R; Zhang L; Seo JH; Xie J; Tucker M; Gu TL; Sudderth J; Jiang L; DeBerardinis RJ; Wu S; Li Y; Mao H; Chen PR; Wang D; Chen GZ; Lonial S; Arellano ML; Khoury HJ; Khuri FR; Lee BH; Brat DJ; Ye K; Boggon TJ; He C; Kang S; Fan J; Chen J
Mol Cell; 2014 Aug; 55(4):552-65. PubMed ID: 25042803
[TBL] [Abstract][Full Text] [Related]
20. Gambogic acid suppresses the pentose phosphate pathway by covalently inhibiting 6PGD protein in cancer cells.
Zhu Y; Zhang Y; Zhang Q; Ma A; Zhang Y; Wang C; Gao P; Guo Q; Xia F; Tang H; Xu C; Wang J
Chem Commun (Camb); 2022 Aug; 58(64):9030-9033. PubMed ID: 35876000
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
