413 related articles for article (PubMed ID: 26491539)
1. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment.
Wang P; Lin M; Pedrosa E; Hrabovsky A; Zhang Z; Guo W; Lachman HM; Zheng D
Mol Autism; 2015; 6():55. PubMed ID: 26491539
[TBL] [Abstract][Full Text] [Related]
2. CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.
Wang P; Mokhtari R; Pedrosa E; Kirschenbaum M; Bayrak C; Zheng D; Lachman HM
Mol Autism; 2017; 8():11. PubMed ID: 28321286
[TBL] [Abstract][Full Text] [Related]
3. Molecular and network disruptions in neurodevelopment uncovered by single cell transcriptomics analysis of
Astorkia M; Liu Y; Pedrosa EM; Lachman HM; Zheng D
bioRxiv; 2023 Sep; ():. PubMed ID: 37808768
[TBL] [Abstract][Full Text] [Related]
4. Gene-Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres.
Modafferi S; Zhong X; Kleensang A; Murata Y; Fagiani F; Pamies D; Hogberg HT; Calabrese V; Lachman H; Hartung T; Smirnova L
Environ Health Perspect; 2021 Jul; 129(7):77001. PubMed ID: 34259569
[TBL] [Abstract][Full Text] [Related]
5. Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.
Shi X; Lu C; Corman A; Nikish A; Zhou Y; Platt RJ; Iossifov I; Zhang F; Pan JQ; Sanjana NE
Am J Hum Genet; 2023 Oct; 110(10):1750-1768. PubMed ID: 37802044
[TBL] [Abstract][Full Text] [Related]
6. The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment.
Cotney J; Muhle RA; Sanders SJ; Liu L; Willsey AJ; Niu W; Liu W; Klei L; Lei J; Yin J; Reilly SK; Tebbenkamp AT; Bichsel C; Pletikos M; Sestan N; Roeder K; State MW; Devlin B; Noonan JP
Nat Commun; 2015 Mar; 6():6404. PubMed ID: 25752243
[TBL] [Abstract][Full Text] [Related]
7. Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development.
Hurley S; Mohan C; Suetterlin P; Ellingford R; Riegman KLH; Ellegood J; Caruso A; Michetti C; Brock O; Evans R; Rudari F; Delogu A; Scattoni ML; Lerch JP; Fernandes C; Basson MA
Mol Autism; 2021 Feb; 12(1):16. PubMed ID: 33627187
[TBL] [Abstract][Full Text] [Related]
8. From X-inactivation to neurodevelopment: CHD8-transcription factors (TFs) competitive binding at regulatory regions of CHD8 target genes can contribute to correct neuronal differentiation.
Cerase A; Avner P
Curr Res Neurobiol; 2023; 5():100114. PubMed ID: 38020809
[TBL] [Abstract][Full Text] [Related]
9. Chromatin Remodeler CHD8 in Autism and Brain Development.
Hoffmann A; Spengler D
J Clin Med; 2021 Jan; 10(2):. PubMed ID: 33477995
[TBL] [Abstract][Full Text] [Related]
10. Autism-specific PTEN p.Ile135Leu variant and an autism genetic background combine to dysregulate cortical neurogenesis.
Fu S; Bury LAD; Eum J; Wynshaw-Boris A
Am J Hum Genet; 2023 May; 110(5):826-845. PubMed ID: 37098352
[TBL] [Abstract][Full Text] [Related]
11. Profiling parvalbumin interneurons using iPSC: challenges and perspectives for Autism Spectrum Disorder (ASD).
Filice F; Schwaller B; Michel TM; Grünblatt E
Mol Autism; 2020 Jan; 11(1):10. PubMed ID: 32000856
[TBL] [Abstract][Full Text] [Related]
12. Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons.
Seabra CM; Aneichyk T; Erdin S; Tai DJC; De Esch CEF; Razaz P; An Y; Manavalan P; Ragavendran A; Stortchevoi A; Abad C; Young JI; Maciel P; Talkowski ME; Gusella JF
Mol Autism; 2020 Jun; 11(1):45. PubMed ID: 32503625
[TBL] [Abstract][Full Text] [Related]
13. Enriched expression of genes associated with autism spectrum disorders in human inhibitory neurons.
Wang P; Zhao D; Lachman HM; Zheng D
Transl Psychiatry; 2018 Jan; 8(1):13. PubMed ID: 29317598
[TBL] [Abstract][Full Text] [Related]
14. Clinical Phenotypes of Carriers of Mutations in CHD8 or Its Conserved Target Genes.
Beighley JS; Hudac CM; Arnett AB; Peterson JL; Gerdts J; Wallace AS; Mefford HC; Hoekzema K; Turner TN; O'Roak BJ; Eichler EE; Bernier RA
Biol Psychiatry; 2020 Jan; 87(2):123-131. PubMed ID: 31526516
[TBL] [Abstract][Full Text] [Related]
15. Atypical Neurogenesis in Induced Pluripotent Stem Cells From Autistic Individuals.
Adhya D; Swarup V; Nagy R; Dutan L; Shum C; Valencia-Alarcón EP; Jozwik KM; Mendez MA; Horder J; Loth E; Nowosiad P; Lee I; Skuse D; Flinter FA; Murphy D; McAlonan G; Geschwind DH; Price J; Carroll J; Srivastava DP; Baron-Cohen S
Biol Psychiatry; 2021 Mar; 89(5):486-496. PubMed ID: 32826066
[TBL] [Abstract][Full Text] [Related]
16.
Wade AA; van den Ameele J; Cheetham SW; Yakob R; Brand AH; Nord AS
iScience; 2021 Nov; 24(11):103234. PubMed ID: 34746699
[TBL] [Abstract][Full Text] [Related]
17. Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex.
Ellingford RA; Tojo M; Basson MA; Andreae LC
ACS Chem Neurosci; 2024 Apr; 15(8):1635-1642. PubMed ID: 38557009
[No Abstract] [Full Text] [Related]
18. Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome.
Tian Y; Voineagu I; Paşca SP; Won H; Chandran V; Horvath S; Dolmetsch RE; Geschwind DH
Genome Med; 2014; 6(10):75. PubMed ID: 25360157
[TBL] [Abstract][Full Text] [Related]
19. Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.
Sorek M; Oweis W; Nissim-Rafinia M; Maman M; Simon S; Hession CC; Adiconis X; Simmons SK; Sanjana NE; Shi X; Lu C; Pan JQ; Xu X; Pouladi MA; Ellerby LM; Zhang F; Levin JZ; Meshorer E
Genome Biol; 2021 Mar; 22(1):73. PubMed ID: 33663567
[TBL] [Abstract][Full Text] [Related]
20. DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders.
Feuer KL; Peng X; Yovo CK; Avramopoulos D
Mol Psychiatry; 2023 Oct; 28(10):4353-4362. PubMed ID: 37479784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
