264 related articles for article (PubMed ID: 26491898)
1. FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12-ATG5 conjugate, leading to the delay of cartilage development in achondroplasia.
Wang X; Qi H; Wang Q; Zhu Y; Wang X; Jin M; Tan Q; Huang Q; Xu W; Li X; Kuang L; Tang Y; Du X; Chen D; Chen L
Autophagy; 2015 Nov; 11(11):1998-2013. PubMed ID: 26491898
[TBL] [Abstract][Full Text] [Related]
2. FGFR3 induces degradation of BMP type I receptor to regulate skeletal development.
Qi H; Jin M; Duan Y; Du X; Zhang Y; Ren F; Wang Y; Tian Q; Wang X; Wang Q; Zhu Y; Xie Y; Liu C; Cao X; Mishina Y; Chen D; Deng CX; Chang Z; Chen L
Biochim Biophys Acta; 2014 Jul; 1843(7):1237-47. PubMed ID: 24657641
[TBL] [Abstract][Full Text] [Related]
3. Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3.
Naski MC; Colvin JS; Coffin JD; Ornitz DM
Development; 1998 Dec; 125(24):4977-88. PubMed ID: 9811582
[TBL] [Abstract][Full Text] [Related]
4. Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotype.
Murakami S; Balmes G; McKinney S; Zhang Z; Givol D; de Crombrugghe B
Genes Dev; 2004 Feb; 18(3):290-305. PubMed ID: 14871928
[TBL] [Abstract][Full Text] [Related]
5. Delayed bone age due to a dual effect of FGFR3 mutation in Achondroplasia.
Pannier S; Mugniery E; Jonquoy A; Benoist-Lasselin C; Odent T; Jais JP; Munnich A; Legeai-Mallet L
Bone; 2010 Nov; 47(5):905-15. PubMed ID: 20673820
[TBL] [Abstract][Full Text] [Related]
6. Progranulin regulation of autophagy contributes to its chondroprotective effect in osteoarthritis.
Pan Y; Yang Y; Fan M; Chen C; Jiang R; Liang L; Xian M; Kuang B; Geng N; Feng N; Deng L; Zheng W; Zhang F; Li X; Guo F
Genes Dis; 2023 Jul; 10(4):1582-1595. PubMed ID: 37397563
[TBL] [Abstract][Full Text] [Related]
7. Achondroplasia: Development, pathogenesis, and therapy.
Ornitz DM; Legeai-Mallet L
Dev Dyn; 2017 Apr; 246(4):291-309. PubMed ID: 27987249
[TBL] [Abstract][Full Text] [Related]
8. BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells.
Lin TY; Chan HH; Chen SH; Sarvagalla S; Chen PS; Coumar MS; Cheng SM; Chang YC; Lin CH; Leung E; Cheung CHA
Autophagy; 2020 Jul; 16(7):1296-1313. PubMed ID: 31612776
[TBL] [Abstract][Full Text] [Related]
9. Differential regulation of endochondral bone growth and joint development by FGFR1 and FGFR3 tyrosine kinase domains.
Wang Q; Green RP; Zhao G; Ornitz DM
Development; 2001 Oct; 128(19):3867-76. PubMed ID: 11585811
[TBL] [Abstract][Full Text] [Related]
10. An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice.
Kimura T; Bosakova M; Nonaka Y; Hruba E; Yasuda K; Futakawa S; Kubota T; Fafilek B; Gregor T; Abraham SP; Gomolkova R; Belaskova S; Pesl M; Csukasi F; Duran I; Fujiwara M; Kavkova M; Zikmund T; Kaiser J; Buchtova M; Krakow D; Nakamura Y; Ozono K; Krejci P
Sci Transl Med; 2021 May; 13(592):. PubMed ID: 33952673
[TBL] [Abstract][Full Text] [Related]
11. A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model.
Jonquoy A; Mugniery E; Benoist-Lasselin C; Kaci N; Le Corre L; Barbault F; Girard AL; Le Merrer Y; Busca P; Schibler L; Munnich A; Legeai-Mallet L
Hum Mol Genet; 2012 Feb; 21(4):841-51. PubMed ID: 22072392
[TBL] [Abstract][Full Text] [Related]
12. Mutant activated FGFR3 impairs endochondral bone growth by preventing SOX9 downregulation in differentiating chondrocytes.
Zhou ZQ; Ota S; Deng C; Akiyama H; Hurlin PJ
Hum Mol Genet; 2015 Mar; 24(6):1764-73. PubMed ID: 25432534
[TBL] [Abstract][Full Text] [Related]
13. Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.
Matsushita M; Kitoh H; Ohkawara B; Mishima K; Kaneko H; Ito M; Masuda A; Ishiguro N; Ohno K
PLoS One; 2013; 8(12):e81569. PubMed ID: 24324705
[TBL] [Abstract][Full Text] [Related]
14. A Ser(365)-->Cys mutation of fibroblast growth factor receptor 3 in mouse downregulates Ihh/PTHrP signals and causes severe achondroplasia.
Chen L; Li C; Qiao W; Xu X; Deng C
Hum Mol Genet; 2001 Mar; 10(5):457-65. PubMed ID: 11181569
[TBL] [Abstract][Full Text] [Related]
15. Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia.
Yamanaka S; Nakao K; Koyama N; Isobe Y; Ueda Y; Kanai Y; Kondo E; Fujii T; Miura M; Yasoda A; Nakao K; Bessho K
J Dent Res; 2017 Dec; 96(13):1526-1534. PubMed ID: 28644737
[TBL] [Abstract][Full Text] [Related]
16. C-Type Natriuretic Peptide Analog as Therapy for Achondroplasia.
Legeai-Mallet L
Endocr Dev; 2016; 30():98-105. PubMed ID: 26684019
[TBL] [Abstract][Full Text] [Related]
17. Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
Martin L; Kaci N; Estibals V; Goudin N; Garfa-Traore M; Benoist-Lasselin C; Dambroise E; Legeai-Mallet L
Hum Mol Genet; 2018 Jan; 27(1):1-13. PubMed ID: 29040558
[TBL] [Abstract][Full Text] [Related]
18. Skeletal dysplasia and defective chondrocyte differentiation by targeted overexpression of fibroblast growth factor 9 in transgenic mice.
Garofalo S; Kliger-Spatz M; Cooke JL; Wolstin O; Lunstrum GP; Moshkovitz SM; Horton WA; Yayon A
J Bone Miner Res; 1999 Nov; 14(11):1909-15. PubMed ID: 10571691
[TBL] [Abstract][Full Text] [Related]
19. Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy.
Otomo C; Metlagel Z; Takaesu G; Otomo T
Nat Struct Mol Biol; 2013 Jan; 20(1):59-66. PubMed ID: 23202584
[TBL] [Abstract][Full Text] [Related]
20. [Molecular basis of achondroplasia, hypochondroplasia, and thanatophoric dysplasia].
Moskalewski S; Hyc A; Osiecka-Iwan A; Strzelczyk P
Chir Narzadow Ruchu Ortop Pol; 2000; 65(3):327-33. PubMed ID: 11057021
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]