BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 26497549)

  • 1. CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma.
    Gao X; Deeb D; Liu Y; Liu P; Zhang Y; Shaw J; Gautam SC
    Int J Oncol; 2015 Dec; 47(6):2100-6. PubMed ID: 26497549
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
    Deeb D; Gao X; Jiang H; Dulchavsky SA; Gautam SC
    Prostate; 2009 Jun; 69(8):851-60. PubMed ID: 19189297
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    J Exp Ther Oncol; 2008; 7(1):31-9. PubMed ID: 18472640
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of cell proliferation and induction of apoptosis by CDDO-Me in pancreatic cancer cells is ROS-dependent.
    Deeb D; Gao X; Liu YB; Gautam SC
    J Exp Ther Oncol; 2012; 10(1):51-64. PubMed ID: 22946344
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
    Gao X; Deeb D; Jiang H; Liu Y; Dulchavsky SA; Gautam SC
    J Neurooncol; 2007 Sep; 84(2):147-57. PubMed ID: 17361329
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthetic oleanane triterpenoid, CDDO-Me, induces apoptosis in ovarian cancer cells by inhibiting prosurvival AKT/NF-κB/mTOR signaling.
    Gao X; Liu Y; Deeb D; Arbab AS; Guo AM; Dulchavsky SA; Gautam SC
    Anticancer Res; 2011 Nov; 31(11):3673-81. PubMed ID: 22110186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methyl 2-cyano-3,12-dioxooleana-1,9-dien-28-oate decreases specificity protein transcription factors and inhibits pancreatic tumor growth: role of microRNA-27a.
    Jutooru I; Chadalapaka G; Abdelrahim M; Basha MR; Samudio I; Konopleva M; Andreeff M; Safe S
    Mol Pharmacol; 2010 Aug; 78(2):226-36. PubMed ID: 20488920
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer.
    Deeb D; Gao X; Arbab AS; Barton K; Dulchavsky SA; Gautam SC
    Cancers (Basel); 2010 Dec; 2(4):1779-93. PubMed ID: 21799944
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.
    Deeb D; Gao X; Liu Y; Varma NR; Arbab AS; Gautam SC
    Molecules; 2013 Mar; 18(3):3250-65. PubMed ID: 23486104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ROS mediate proapoptotic and antisurvival activity of oleanane triterpenoid CDDO-Me in ovarian cancer cells.
    Gao X; Liu Y; Deeb D; Liu P; Liu A; Arbab AS; Gautam SC
    Anticancer Res; 2013 Jan; 33(1):215-21. PubMed ID: 23267148
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oleanane triterpenoid CDDO-Me inhibits Akt activity without affecting PDK1 kinase or PP2A phosphatase activity in cancer cells.
    Liu Y; Gao X; Deeb D; Gautam SC
    Biochem Biophys Res Commun; 2012 Jan; 417(1):570-5. PubMed ID: 22177954
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activity.
    Deeb D; Gao X; Liu Y; Kim SH; Pindolia KR; Arbab AS; Gautam SC
    Biochem Biophys Res Commun; 2012 Jun; 422(4):561-7. PubMed ID: 22609405
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancer.
    Liu Y; Gao X; Deeb D; Arbab AS; Gautam SC
    Molecules; 2012 Dec; 17(12):14795-809. PubMed ID: 23519253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CDDO-me induces apoptosis and inhibits Akt, mTOR and NF-kappaB signaling proteins in prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    Anticancer Res; 2007; 27(5A):3035-44. PubMed ID: 17970042
    [TBL] [Abstract][Full Text] [Related]  

  • 15. c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.
    Zou W; Chen S; Liu X; Yue P; Sporn MB; Khuri FR; Sun SY
    Cancer Biol Ther; 2007 Oct; 6(10):1614-20. PubMed ID: 18253090
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
    Kim KB; Lotan R; Yue P; Sporn MB; Suh N; Gribble GW; Honda T; Wu GS; Hong WK; Sun SY
    Mol Cancer Ther; 2002 Jan; 1(3):177-84. PubMed ID: 12467212
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer.
    Gao X; Deeb D; Liu Y; Arbab AS; Divine GW; Dulchavsky SA; Gautam SC
    Cancers (Basel); 2011; 3(3):3353-69. PubMed ID: 21961053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.
    Zou W; Liu X; Yue P; Zhou Z; Sporn MB; Lotan R; Khuri FR; Sun SY
    Cancer Res; 2004 Oct; 64(20):7570-8. PubMed ID: 15492284
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hsp90 Is a Novel Target Molecule of CDDO-Me in Inhibiting Proliferation of Ovarian Cancer Cells.
    Qin DJ; Tang CX; Yang L; Lei H; Wei W; Wang YY; Ma CM; Gao FH; Xu HZ; Wu YL
    PLoS One; 2015; 10(7):e0132337. PubMed ID: 26134508
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.