These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint. Navadgi-Patil VM; Kumar S; Burgers PM J Biol Chem; 2011 Nov; 286(47):40999-1007. PubMed ID: 21956112 [TBL] [Abstract][Full Text] [Related]
3. The unstructured C-terminal tail of the 9-1-1 clamp subunit Ddc1 activates Mec1/ATR via two distinct mechanisms. Navadgi-Patil VM; Burgers PM Mol Cell; 2009 Dec; 36(5):743-53. PubMed ID: 20005839 [TBL] [Abstract][Full Text] [Related]
4. A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1. Navadgi-Patil VM; Burgers PM DNA Repair (Amst); 2009 Sep; 8(9):996-1003. PubMed ID: 19464966 [TBL] [Abstract][Full Text] [Related]
5. Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts. Biswas H; Goto G; Wang W; Sung P; Sugimoto K PLoS Genet; 2019 Aug; 15(8):e1008294. PubMed ID: 31369547 [TBL] [Abstract][Full Text] [Related]
6. Yet another job for Dna2: Checkpoint activation. Wanrooij PH; Burgers PM DNA Repair (Amst); 2015 Aug; 32():17-23. PubMed ID: 25956863 [TBL] [Abstract][Full Text] [Related]
7. Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase. Navadgi-Patil VM; Burgers PM J Biol Chem; 2008 Dec; 283(51):35853-9. PubMed ID: 18922789 [TBL] [Abstract][Full Text] [Related]
8. Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery. Kumar S; Burgers PM Genes Dev; 2013 Feb; 27(3):313-21. PubMed ID: 23355394 [TBL] [Abstract][Full Text] [Related]
10. Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism. Bandhu A; Kang J; Fukunaga K; Goto G; Sugimoto K PLoS Genet; 2014 Feb; 10(2):e1004136. PubMed ID: 24586187 [TBL] [Abstract][Full Text] [Related]
11. Clamping the Mec1/ATR checkpoint kinase into action. Majka J; Burgers PM Cell Cycle; 2007 May; 6(10):1157-60. PubMed ID: 17495536 [TBL] [Abstract][Full Text] [Related]
12. Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo. Berens TJ; Toczyski DP Mol Biol Cell; 2012 Mar; 23(6):1058-67. PubMed ID: 22298423 [TBL] [Abstract][Full Text] [Related]
13. Mec1 Memisoglu G; Lanz MC; Eapen VV; Jordan JM; Lee K; Smolka MB; Haber JE Cell Rep; 2019 Jul; 28(4):1090-1102.e3. PubMed ID: 31340146 [TBL] [Abstract][Full Text] [Related]
14. Dpb11 activates the Mec1-Ddc2 complex. Mordes DA; Nam EA; Cortez D Proc Natl Acad Sci U S A; 2008 Dec; 105(48):18730-4. PubMed ID: 19028869 [TBL] [Abstract][Full Text] [Related]
15. Preparation of endogenous TopBP1/Dpb11 and effect on central checkpoint kinase Mec1- Ddc2 (human ATR-ATRIP homolog). Wu T; Zhang Z; Wang X Biochem Biophys Res Commun; 2019 Sep; 517(2):291-296. PubMed ID: 31349966 [TBL] [Abstract][Full Text] [Related]
16. Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling. Lanz MC; Oberly S; Sanford EJ; Sharma S; Chabes A; Smolka MB Genes Dev; 2018 Jun; 32(11-12):822-835. PubMed ID: 29899143 [TBL] [Abstract][Full Text] [Related]
18. Four pillars of the S-phase checkpoint. Zou L Genes Dev; 2013 Feb; 27(3):227-33. PubMed ID: 23388823 [TBL] [Abstract][Full Text] [Related]
19. Activation of ATR-related protein kinase upon DNA damage recognition. Ma M; Rodriguez A; Sugimoto K Curr Genet; 2020 Apr; 66(2):327-333. PubMed ID: 31624858 [TBL] [Abstract][Full Text] [Related]
20. Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway. Donnianni RA; Ferrari M; Lazzaro F; Clerici M; Tamilselvan Nachimuthu B; Plevani P; Muzi-Falconi M; Pellicioli A PLoS Genet; 2010 Jan; 6(1):e1000763. PubMed ID: 20098491 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]