BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 26506135)

  • 1. GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels.
    Sato PY; Chuprun JK; Ibetti J; Cannavo A; Drosatos K; Elrod JW; Koch WJ
    J Mol Cell Cardiol; 2015 Dec; 89(Pt B):360-4. PubMed ID: 26506135
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting.
    Chen M; Sato PY; Chuprun JK; Peroutka RJ; Otis NJ; Ibetti J; Pan S; Sheu SS; Gao E; Koch WJ
    Circ Res; 2013 Apr; 112(8):1121-34. PubMed ID: 23467820
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.
    Sato PY; Chuprun JK; Grisanti LA; Woodall MC; Brown BR; Roy R; Traynham CJ; Ibetti J; Lucchese AM; Yuan A; Drosatos K; Tilley DG; Gao E; Koch WJ
    Sci Signal; 2018 Dec; 11(560):. PubMed ID: 30538174
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G protein-coupled receptor kinase 2 contributes to impaired fatty acid metabolism in the failing heart.
    Pfleger J; Gross P; Johnson J; Carter RL; Gao E; Tilley DG; Houser SR; Koch WJ
    J Mol Cell Cardiol; 2018 Oct; 123():108-117. PubMed ID: 30171848
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Myocardial GRK2 Reduces Fatty Acid Metabolism and β-Adrenergic Receptor-Mediated Mitochondrial Responses.
    Zhai R; Varner EL; Rao A; Karhadkar S; Di Carlo A; Snyder NW; Sato PY
    Int J Mol Sci; 2022 Mar; 23(5):. PubMed ID: 35269919
    [TBL] [Abstract][Full Text] [Related]  

  • 6. G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.
    Ciccarelli M; Chuprun JK; Rengo G; Gao E; Wei Z; Peroutka RJ; Gold JI; Gumpert A; Chen M; Otis NJ; Dorn GW; Trimarco B; Iaccarino G; Koch WJ
    Circulation; 2011 May; 123(18):1953-62. PubMed ID: 21518983
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.
    Abd Alla J; Graemer M; Fu X; Quitterer U
    J Biol Chem; 2016 Feb; 291(6):2583-600. PubMed ID: 26670611
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels.
    Lucas E; Vila-Bedmar R; Arcones AC; Cruces-Sande M; Cachofeiro V; Mayor F; Murga C
    Cardiovasc Diabetol; 2016 Nov; 15(1):155. PubMed ID: 27832814
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.
    Fan Q; Chen M; Zuo L; Shang X; Huang MZ; Ciccarelli M; Raake P; Brinks H; Chuprun KJ; Dorn GW; Koch WJ; Gao E
    PLoS One; 2013; 8(6):e66234. PubMed ID: 23805205
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gβγ-independent recruitment of G-protein coupled receptor kinase 2 drives tumor necrosis factor α-induced cardiac β-adrenergic receptor dysfunction.
    Vasudevan NT; Mohan ML; Gupta MK; Martelli EE; Hussain AK; Qin Y; Chandrasekharan UM; Young D; Feldman AM; Sen S; Dorn GW; Dicorleto PE; Naga Prasad SV
    Circulation; 2013 Jul; 128(4):377-87. PubMed ID: 23785004
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C.
    Malhotra R; D'Souza KM; Staron ML; Birukov KG; Bodi I; Akhter SA
    J Biol Chem; 2010 Apr; 285(18):13748-60. PubMed ID: 20194499
    [TBL] [Abstract][Full Text] [Related]  

  • 12. G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells.
    Manfredi LH; Ang J; Peker N; Dagda RK; McFarlane C
    Am J Physiol Cell Physiol; 2019 Oct; 317(4):C674-C686. PubMed ID: 31268780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G protein receptor kinase.
    Dal-Secco D; DalBó S; Lautherbach NES; Gava FN; Celes MRN; Benedet PO; Souza AH; Akinaga J; Lima V; Silva KP; Kiguti LRA; Rossi MA; Kettelhut IC; Pupo AS; Cunha FQ; Assreuy J
    Am J Physiol Heart Circ Physiol; 2017 Jul; 313(1):H149-H163. PubMed ID: 28526706
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Calcineurin transgenic mice have mitochondrial dysfunction and elevated superoxide production.
    Sayen MR; Gustafsson AB; Sussman MA; Molkentin JD; Gottlieb RA
    Am J Physiol Cell Physiol; 2003 Feb; 284(2):C562-70. PubMed ID: 12397029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antagonistic Roles of GRK2 and GRK5 in Cardiac Aldosterone Signaling Reveal GRK5-Mediated Cardioprotection via Mineralocorticoid Receptor Inhibition.
    Maning J; McCrink KA; Pollard CM; Desimine VL; Ghandour J; Perez A; Cora N; Ferraino KE; Parker BM; Brill AR; Aukszi B; Lymperopoulos A
    Int J Mol Sci; 2020 Apr; 21(8):. PubMed ID: 32326036
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Impaired substrate-mediated cardiac mitochondrial complex I respiration with unaltered regulation of fatty acid metabolism and oxidative stress status in type 2 diabetic Asian Indians.
    Jayakumari NR; Rajendran RS; Sivasailam A; Vimala SS; Nanda S; Manjunatha S; Pillai VV; Karunakaran J; Gopala S
    J Diabetes; 2020 Jul; 12(7):542-555. PubMed ID: 32125087
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial G protein coupled receptor kinase 2 regulates proinflammatory responses in macrophages.
    Sorriento D; Fusco A; Ciccarelli M; Rungi A; Anastasio A; Carillo A; Dorn GW; Trimarco B; Iaccarino G
    FEBS Lett; 2013 Nov; 587(21):3487-94. PubMed ID: 24036448
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling.
    Jean-Charles PY; Yu SM; Abraham D; Kommaddi RP; Mao L; Strachan RT; Zhang ZS; Bowles DE; Brian L; Stiber JA; Jones SN; Koch WJ; Rockman HA; Shenoy SK
    JCI Insight; 2017 Sep; 2(17):. PubMed ID: 28878120
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondrial Calpain-1 Disrupts ATP Synthase and Induces Superoxide Generation in Type 1 Diabetic Hearts: A Novel Mechanism Contributing to Diabetic Cardiomyopathy.
    Ni R; Zheng D; Xiong S; Hill DJ; Sun T; Gardiner RB; Fan GC; Lu Y; Abel ED; Greer PA; Peng T
    Diabetes; 2016 Jan; 65(1):255-68. PubMed ID: 26470784
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.
    Raake PW; Vinge LE; Gao E; Boucher M; Rengo G; Chen X; DeGeorge BR; Matkovich S; Houser SR; Most P; Eckhart AD; Dorn GW; Koch WJ
    Circ Res; 2008 Aug; 103(4):413-22. PubMed ID: 18635825
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.