325 related articles for article (PubMed ID: 26510874)
1. Transgenic Wuzhishan minipigs designed to express a dominant-negative porcine growth hormone receptor display small stature and a perturbed insulin/IGF-1 pathway.
Li F; Li Y; Liu H; Zhang X; Liu C; Tian K; Bolund L; Dou H; Yang W; Yang H; Staunstrup NH; Du Y
Transgenic Res; 2015 Dec; 24(6):1029-42. PubMed ID: 26510874
[TBL] [Abstract][Full Text] [Related]
2. Generation of a miniature pig disease model for human Laron syndrome.
Cui D; Li F; Li Q; Li J; Zhao Y; Hu X; Zhang R; Li N
Sci Rep; 2015 Oct; 5():15603. PubMed ID: 26511035
[TBL] [Abstract][Full Text] [Related]
3. Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
Hinrichs A; Kessler B; Kurome M; Blutke A; Kemter E; Bernau M; Scholz AM; Rathkolb B; Renner S; Bultmann S; Leonhardt H; de Angelis MH; Nagashima H; Hoeflich A; Blum WF; Bidlingmaier M; Wanke R; Dahlhoff M; Wolf E
Mol Metab; 2018 May; 11():113-128. PubMed ID: 29678421
[TBL] [Abstract][Full Text] [Related]
4. Primary growth hormone (GH) insensitivity and insulin-like growth factor deficiency caused by novel compound heterozygous mutations of the GH receptor gene: genetic and functional studies of simple and compound heterozygous states.
Fang P; Riedl S; Amselem S; Pratt KL; Little BM; Haeusler G; Hwa V; Frisch H; Rosenfeld RG
J Clin Endocrinol Metab; 2007 Jun; 92(6):2223-31. PubMed ID: 17405847
[TBL] [Abstract][Full Text] [Related]
5. Growth Hormone Receptor Mutations Related to Individual Dwarfism.
Lin S; Li C; Li C; Zhang X
Int J Mol Sci; 2018 May; 19(5):. PubMed ID: 29748515
[TBL] [Abstract][Full Text] [Related]
6. Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.
Yu H; Long W; Zhang X; Xu K; Guo J; Zhao H; Li H; Qing Y; Pan W; Jia B; Zhao HY; Huang X; Wei HJ
J Transl Med; 2018 Feb; 16(1):41. PubMed ID: 29482569
[TBL] [Abstract][Full Text] [Related]
7. Growth hormone insensitivity syndrome caused by a heterozygous GHR mutation: phenotypic variability owing to moderation by nonsense-mediated decay.
Gorbenko del Blanco D; de Graaff LC; Visser TJ; Hokken-Koelega AC
Clin Endocrinol (Oxf); 2012 May; 76(5):706-12. PubMed ID: 22117696
[TBL] [Abstract][Full Text] [Related]
8. Short stature and decreased insulin-like growth factor I (IGF-I)/growth hormone (GH)-ratio in an adult GH-deficient patient pointing to additional partial GH insensitivity due to a R179C mutation of the growth hormone receptor.
Meyer S; Ipek M; Keth A; Minnemann T; von Mach MA; Weise A; Ittner JR; Nawroth PP; Plöckinger U; Stalla GK; Tuschy U; Weber MM; Kann PH; ;
Growth Horm IGF Res; 2007 Aug; 17(4):307-14. PubMed ID: 17462934
[TBL] [Abstract][Full Text] [Related]
9. The growth hormone receptor (GHR) c.899dupC mutation functions as a dominant negative: insights into the pathophysiology of intracellular GHR defects.
Derr MA; Aisenberg J; Fang P; Tenenbaum-Rakover Y; Rosenfeld RG; Hwa V
J Clin Endocrinol Metab; 2011 Nov; 96(11):E1896-904. PubMed ID: 21900382
[TBL] [Abstract][Full Text] [Related]
10. Atypical defects resulting in growth hormone insensitivity.
Wit JM; de Luca F
Growth Horm IGF Res; 2016 Jun; 28():57-61. PubMed ID: 26670721
[TBL] [Abstract][Full Text] [Related]
11. Pancreatic islet-specific expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-deficient mice.
Guo Y; Lu Y; Houle D; Robertson K; Tang Z; Kopchick JJ; Liu YL; Liu JL
Endocrinology; 2005 Jun; 146(6):2602-9. PubMed ID: 15731363
[TBL] [Abstract][Full Text] [Related]
12. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse).
Zhou Y; Xu BC; Maheshwari HG; He L; Reed M; Lozykowski M; Okada S; Cataldo L; Coschigamo K; Wagner TE; Baumann G; Kopchick JJ
Proc Natl Acad Sci U S A; 1997 Nov; 94(24):13215-20. PubMed ID: 9371826
[TBL] [Abstract][Full Text] [Related]
13. Clinical and Molecular Features of Laron Syndrome, A Genetic Disorder Protecting from Cancer.
Janecka A; Kołodziej-Rzepa M; Biesaga B
In Vivo; 2016; 30(4):375-81. PubMed ID: 27381597
[TBL] [Abstract][Full Text] [Related]
14. Tissue-specific regulation of growth hormone (GH) receptor and insulin-like growth factor-I gene expression in the pituitary and liver of GH-deficient (lit/lit) mice and transgenic mice that overexpress bovine GH (bGH) or a bGH antagonist.
Iida K; Del Rincon JP; Kim DS; Itoh E; Nass R; Coschigano KT; Kopchick JJ; Thorner MO
Endocrinology; 2004 Apr; 145(4):1564-70. PubMed ID: 14726438
[TBL] [Abstract][Full Text] [Related]
15. MECHANISMS IN ENDOCRINOLOGY: Transient juvenile hypoglycemia in growth hormone receptor deficiency - mechanistic insights from Laron syndrome and tailored animal models.
Hinrichs A; Renner S; Bidlingmaier M; Kopchick JJ; Wolf E
Eur J Endocrinol; 2021 Jul; 185(2):R35-R47. PubMed ID: 34048365
[TBL] [Abstract][Full Text] [Related]
16. The Effect of GHR/exon-3 Polymorphism and Serum GH, IGF-1 and IGFBP-3 Levels in Diabetes and Coronary Heart Disease.
Kucukhuseyin O; Toptas B; Timirci-Kahraman O; Isbir S; Karsidag K; Isbir T
In Vivo; 2015; 29(3):371-8. PubMed ID: 25977383
[TBL] [Abstract][Full Text] [Related]
17. Serum IGF-1 is insufficient to restore skeletal size in the total absence of the growth hormone receptor.
Wu Y; Sun H; Basta-Pljakic J; Cardoso L; Kennedy OD; Jasper H; Domené H; Karabatas L; Guida C; Schaffler MB; Rosen CJ; Yakar S
J Bone Miner Res; 2013 Jul; 28(7):1575-86. PubMed ID: 23456957
[TBL] [Abstract][Full Text] [Related]
18. Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
Riedel EO; Hinrichs A; Kemter E; Dahlhoff M; Backman M; Rathkolb B; Prehn C; Adamski J; Renner S; Blutke A; de Angelis MH; Bidlingmaier M; Schopohl J; Arnold GJ; Fröhlich T; Wolf E
Mol Metab; 2020 Jun; 36():100978. PubMed ID: 32277923
[TBL] [Abstract][Full Text] [Related]
19. Novel growth hormone receptor gene mutation in a patient with Laron syndrome.
Arman A; Yüksel B; Coker A; Sarioz O; Temiz F; Topaloglu AK
J Pediatr Endocrinol Metab; 2010 Apr; 23(4):407-14. PubMed ID: 20583548
[TBL] [Abstract][Full Text] [Related]
20. Clinical features and growth hormone receptor gene mutations of patients with Laron syndrome from a Chinese family.
Ying YQ; Wei H; Cao LZ; Lu JJ; Luo XP
Zhongguo Dang Dai Er Ke Za Zhi; 2007 Aug; 9(4):335-8. PubMed ID: 17706034
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
