BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 26515064)

  • 21. Combinatorial mutagenesis with alternative CDR-L1 and -H2 loop lengths contributes to affinity maturation of antibodies.
    Brockmann EC; Pyykkö M; Hannula H; Khan K; Lamminmäki U; Huovinen T
    N Biotechnol; 2021 Jan; 60():173-182. PubMed ID: 33039698
    [TBL] [Abstract][Full Text] [Related]  

  • 22. An integrated approach to extreme thermostabilization and affinity maturation of an antibody.
    McConnell AD; Spasojevich V; Macomber JL; Krapf IP; Chen A; Sheffer JC; Berkebile A; Horlick RA; Neben S; King DJ; Bowers PM
    Protein Eng Des Sel; 2013 Feb; 26(2):151-64. PubMed ID: 23173178
    [TBL] [Abstract][Full Text] [Related]  

  • 23. More than 370-Fold Increase in Antibody Affinity to Estradiol-17β by Exploring Substitutions in the V
    Morita I; Kiguchi Y; Nakamura S; Yoshida A; Kubo H; Ishida M; Oyama H; Kobayashi N
    Biol Pharm Bull; 2022; 45(7):851-855. PubMed ID: 35786593
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Conversion of scFv peptide-binding specificity for crystal chaperone development.
    Pai JC; Culver JA; Drury JE; Motani RS; Lieberman RL; Maynard JA
    Protein Eng Des Sel; 2011 May; 24(5):419-28. PubMed ID: 21217145
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Impact of scFv structure in chimeric antigen receptor on receptor expression efficiency and antigen recognition properties.
    Fujiwara K; Masutani M; Tachibana M; Okada N
    Biochem Biophys Res Commun; 2020 Jun; 527(2):350-357. PubMed ID: 32216966
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries.
    Burmester J; Spinelli S; Pugliese L; Krebber A; Honegger A; Jung S; Schimmele B; Cambillau C; Plückthun A
    J Mol Biol; 2001 Jun; 309(3):671-85. PubMed ID: 11397088
    [TBL] [Abstract][Full Text] [Related]  

  • 27. DNA binding by the VH domain of anti-Z-DNA antibody and its modulation by association of the VL domain.
    Chen Y; Stollar BD
    J Immunol; 1999 Apr; 162(8):4663-70. PubMed ID: 10202006
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Selection of affinity-improved neutralizing human scFv against HBV PreS1 from CDR3 VH/VL mutant library.
    Chen Y; Bai Y; Guo X; Wang W; Zheng Q; Wang F; Sun D; Li D; Ren G; Yin J
    Biologicals; 2016 Jul; 44(4):271-275. PubMed ID: 27255707
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Affinity maturation and fine functional mapping of an antibody fragment against a novel neutralizing epitope on human vascular endothelial growth factor.
    Lamdan H; Gavilondo JV; Muñoz Y; Pupo A; Huerta V; Musacchio A; Pérez L; Ayala M; Rojas G; Balint RF; Larrick JW
    Mol Biosyst; 2013 Aug; 9(8):2097-106. PubMed ID: 23702826
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Decomposing Dynamical Couplings in Mutated scFv Antibody Fragments into Stabilizing and Destabilizing Effects.
    Ettayapuram Ramaprasad AS; Uddin S; Casas-Finet J; Jacobs DJ
    J Am Chem Soc; 2017 Dec; 139(48):17508-17517. PubMed ID: 29139290
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Computational identification of antigen-binding antibody fragments.
    Burkovitz A; Leiderman O; Sela-Culang I; Byk G; Ofran Y
    J Immunol; 2013 Mar; 190(5):2327-34. PubMed ID: 23359499
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Secretion from bacterial versus mammalian cells yields a recombinant scFv with variable folding properties.
    Vendel MC; Favis M; Snyder WB; Huang F; Capili AD; Dong J; Glaser SM; Miller BR; Demarest SJ
    Arch Biochem Biophys; 2012 Oct; 526(2):188-93. PubMed ID: 22230329
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Affinity maturation of antibodies by combinatorial codon mutagenesis versus error-prone PCR.
    Simons JF; Lim YW; Carter KP; Wagner EK; Wayham N; Adler AS; Johnson DS
    MAbs; 2020; 12(1):1803646. PubMed ID: 32744131
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Construction of an scFv library by enzymatic assembly of V(L) and V(H) genes.
    Kato M; Hanyu Y
    J Immunol Methods; 2013 Oct; 396(1-2):15-22. PubMed ID: 23916870
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Complementarity determining regions and frameworks contribute to the disulfide bond independent folding of intrinsically stable scFv.
    Gąciarz A; Ruddock LW
    PLoS One; 2017; 12(12):e0189964. PubMed ID: 29253024
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Cloning and molecular characterization of the cDNAs encoding the variable regions of an anti-CD20 monoclonal antibody.
    Shanehbandi D; Majidi J; Kazemi T; Baradaran B; Aghebati-Maleki L
    Hum Antibodies; 2017; 26(1):1-6. PubMed ID: 28269762
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Improving the affinity of an antibody for its antigen via long-range electrostatic interactions.
    Fukunaga A; Tsumoto K
    Protein Eng Des Sel; 2013 Dec; 26(12):773-80. PubMed ID: 24214686
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Cell- and nuclear-penetrating anti-dsDNA autoantibodies have multiple arginines in CDR3 of VH and increase cellular level of pERK and Bcl-2 in mesangial cells.
    Im SR; Im SW; Chung HY; Pravinsagar P; Jang YJ
    Mol Immunol; 2015 Oct; 67(2 Pt B):377-87. PubMed ID: 26189065
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains.
    Nilvebrant J; Ereño-Orbea J; Gorelik M; Julian MC; Tessier PM; Julien JP; Sidhu SS
    J Mol Biol; 2021 Oct; 433(21):167241. PubMed ID: 34508727
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A semi-synthetic repertoire of intrinsically stable antibody fragments derived from a single-framework scaffold.
    Desiderio A; Franconi R; Lopez M; Villani ME; Viti F; Chiaraluce R; Consalvi V; Neri D; Benvenuto E
    J Mol Biol; 2001 Jul; 310(3):603-15. PubMed ID: 11439027
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.