These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

88 related articles for article (PubMed ID: 26516585)

  • 1. Interrogating the relationship between rat in vivo tissue distribution and drug property data for >200 structurally unrelated molecules.
    Harrell AW; Sychterz C; Ho MY; Weber A; Valko K; Negash K
    Pharmacol Res Perspect; 2015 Oct; 3(5):e00173. PubMed ID: 26516585
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The distribution pattern of radioactivity across different tissues in quantitative whole-body autoradiography (QWBA) studies.
    Richter WF; Starke V; Whitby B
    Eur J Pharm Sci; 2006 May; 28(1-2):155-65. PubMed ID: 16510271
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Utility of quantitative whole-body autoradiography (QWBA) and imaging mass spectrometry (IMS) by matrix-assisted laser desorption/ionization (MALDI) in the assessment of ocular distribution of drugs.
    Drexler DM; Tannehill-Gregg SH; Wang L; Brock BJ
    J Pharmacol Toxicol Methods; 2011; 63(2):205-8. PubMed ID: 21040797
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Physicochemical factors associated with binding and retention of compounds in ocular melanin of rats: correlations using data from whole-body autoradiography and molecular modeling for multiple linear regression analyses.
    Zane PA; Brindle SD; Gause DO; O'Buck AJ; Raghavan PR; Tripp SL
    Pharm Res; 1990 Sep; 7(9):935-41. PubMed ID: 2235893
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition.
    Poulin P; Theil FP
    J Pharm Sci; 2002 May; 91(5):1358-70. PubMed ID: 11977112
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Use of radioactive compounds and autoradiography to determine drug tissue distribution.
    Solon EG
    Chem Res Toxicol; 2012 Mar; 25(3):543-55. PubMed ID: 22280496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Absorption, distribution and excretion of 14C-chloroquine after single oral administration in albino and pigmented rats: binding characteristics of chloroquine-related radioactivity to melanin in-vivo.
    Ono C; Yamada M; Tanaka M
    J Pharm Pharmacol; 2003 Dec; 55(12):1647-54. PubMed ID: 14738591
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A paradigm shift in pharmacokinetic-pharmacodynamic (PKPD) modeling: rule of thumb for estimating free drug level in tissue compared with plasma to guide drug design.
    Poulin P
    J Pharm Sci; 2015 Jul; 104(7):2359-68. PubMed ID: 25943586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The distribution pattern of intravenous [(14)C] artesunate in rat tissues by quantitative whole-body autoradiography and tissue dissection techniques.
    Li Q; Xie L; Zhang J; Weina PJ
    J Pharm Biomed Anal; 2008 Nov; 48(3):876-84. PubMed ID: 18762400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A priori prediction of tissue:plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery.
    Poulin P; Theil FP
    J Pharm Sci; 2000 Jan; 89(1):16-35. PubMed ID: 10664535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A rapid LC-MS/MS method for the quantitation of a series of benzonaphthyridine derivatives: application to in vivo pharmacokinetic and lipophilicity studies in drug development.
    Lukka PB; Paxton JW; Atwell GJ; Kestell P; Baguley BC
    J Pharm Biomed Anal; 2012 Apr; 63():9-16. PubMed ID: 22361659
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lipophilicity and biomimetic properties measured by HPLC to support drug discovery.
    Valkó KL
    J Pharm Biomed Anal; 2016 Oct; 130():35-54. PubMed ID: 27084527
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The prediction of drug metabolism, tissue distribution, and bioavailability of 50 structurally diverse compounds in rat using mechanism-based absorption, distribution, and metabolism prediction tools.
    De Buck SS; Sinha VK; Fenu LA; Gilissen RA; Mackie CE; Nijsen MJ
    Drug Metab Dispos; 2007 Apr; 35(4):649-59. PubMed ID: 17267621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: new set of data for predictive in silico ADME models.
    Fortuna A; Alves G; Soares-da-Silva P; Falcão A
    Epilepsy Res; 2013 Nov; 107(1-2):37-50. PubMed ID: 24050973
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example.
    Eikel D; Vavrek M; Smith S; Bason C; Yeh S; Korfmacher WA; Henion JD
    Rapid Commun Mass Spectrom; 2011 Dec; 25(23):3587-96. PubMed ID: 22095508
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapid and specific targeting of 125I-labeled B lymphocyte stimulator to lymphoid tissues and B cell tumors in mice.
    Riccobene TA; Miceli RC; Lincoln C; Knight Y; Meadows J; Stabin MG; Sung C
    J Nucl Med; 2003 Mar; 44(3):422-33. PubMed ID: 12621010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetics and tissue distribution of galantamine and galantamine-related radioactivity after single intravenous and oral administration in the rat.
    van Beijsterveldt L; Geerts R; Verhaeghe T; Willems B; Bode W; Lavrijsen K; Meuldermans W
    Arzneimittelforschung; 2004; 54(2):85-94. PubMed ID: 15038457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison between immobilized artificial membrane (IAM) HPLC data and lipophilicity in n-octanol for quinolone antibacterial agents.
    Barbato F; Cirocco V; Grumetto L; Immacolata La Rotonda M
    Eur J Pharm Sci; 2007 Aug; 31(5):288-97. PubMed ID: 17540545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Integration of in silico and in vitro tools for scaffold optimization during drug discovery: predicting P-glycoprotein efflux.
    Desai PV; Sawada GA; Watson IA; Raub TJ
    Mol Pharm; 2013 Apr; 10(4):1249-61. PubMed ID: 23363443
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on the melanin affinity of haloperidol.
    Lydén A; Larsson B; Lindquist NG
    Arch Int Pharmacodyn Ther; 1982 Oct; 259(2):230-43. PubMed ID: 7181580
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.