BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

109 related articles for article (PubMed ID: 26521679)

  • 1. Impact of vitamin C on the cardiometabolic and inflammatory profiles of mice lacking a functional Werner syndrome protein helicase.
    Aumailley L; Dubois MJ; Garand C; Marette A; Lebel M
    Exp Gerontol; 2015 Dec; 72():192-203. PubMed ID: 26521679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice.
    Aumailley L; Garand C; Dubois MJ; Johnson FB; Marette A; Lebel M
    PLoS One; 2015; 10(10):e0140292. PubMed ID: 26447695
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional Werner syndrome (Wrn) mutant protein.
    Aumailley L; Roux-Dalvai F; Kelly I; Droit A; Lebel M
    PLoS One; 2018; 13(3):e0193170. PubMed ID: 29494634
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vitamin C restores healthy aging in a mouse model for Werner syndrome.
    Massip L; Garand C; Paquet ER; Cogger VC; O'Reilly JN; Tworek L; Hatherell A; Taylor CG; Thorin E; Zahradka P; Le Couteur DG; Lebel M
    FASEB J; 2010 Jan; 24(1):158-72. PubMed ID: 19741171
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Serum vitamin C levels modulate the lifespan and endoplasmic reticulum stress response pathways in mice synthesizing a nonfunctional mutant WRN protein.
    Aumailley L; Dubois MJ; Brennan TA; Garand C; Paquet ER; Pignolo RJ; Marette A; Lebel M
    FASEB J; 2018 Jul; 32(7):3623-3640. PubMed ID: 29452565
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.
    Hui CW; St-Pierre MK; Detuncq J; Aumailley L; Dubois MJ; Couture V; Skuk D; Marette A; Tremblay JP; Lebel M; Tremblay MÈ
    Brain Behav Immun; 2018 Oct; 73():450-469. PubMed ID: 29908963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin.
    Lebel M; Massip L; Garand C; Thorin E
    Ann N Y Acad Sci; 2010 Jun; 1197():40-4. PubMed ID: 20536831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide.
    Labbé A; Turaga RV; Paquet ER; Garand C; Lebel M
    BMC Genomics; 2010 Feb; 11():127. PubMed ID: 20175907
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.
    Yamamoto ML; Reliene R; Oshima J; Schiestl RH
    Mutat Res; 2008 Sep; 644(1-2):11-6. PubMed ID: 18639560
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging.
    Dallaire A; Garand C; Paquel ER; Mitchell SJ; de Cabo R; Simard MJ; Lebel M
    Aging (Albany NY); 2012 Sep; 4(9):636-47. PubMed ID: 23075628
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Impact of Vitamin C on Different System Models of Werner Syndrome.
    Aumailley L; Lebel M
    Antioxid Redox Signal; 2021 Apr; 34(11):856-874. PubMed ID: 33202145
    [No Abstract]   [Full Text] [Related]  

  • 12. Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome.
    Labbé A; Garand C; Cogger VC; Paquet ER; Desbiens M; Le Couteur DG; Lebel M
    J Gerontol A Biol Sci Med Sci; 2011 Mar; 66(3):264-78. PubMed ID: 20974729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span.
    Dallaire A; Proulx S; Simard MJ; Lebel M
    BMC Genomics; 2014 Oct; 15(1):940. PubMed ID: 25346348
    [TBL] [Abstract][Full Text] [Related]  

  • 14. WRN polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts.
    Castro E; Oviedo-Rodríguez V; Angel-Chávez LI
    BMC Cardiovasc Disord; 2008 Feb; 8():5. PubMed ID: 18312663
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Werner syndrome helicase protein is required for cell proliferation, immortalization, and tumorigenesis in Scaffold attachment factor B1 deficient mice.
    Lachapelle S; Oesterreich S; Lebel M
    Aging (Albany NY); 2011 Mar; 3(3):277-90. PubMed ID: 21464516
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.
    Cheng WH; Muftuoglu M; Bohr VA
    Exp Gerontol; 2007 Sep; 42(9):871-8. PubMed ID: 17587522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Telomere ResQue and preservation--roles for the Werner syndrome protein and other RecQ helicases.
    Opresko PL
    Mech Ageing Dev; 2008; 129(1-2):79-90. PubMed ID: 18054793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Vitamin C alleviates aging defects in a stem cell model for Werner syndrome.
    Li Y; Zhang W; Chang L; Han Y; Sun L; Gong X; Tang H; Liu Z; Deng H; Ye Y; Wang Y; Li J; Qiao J; Qu J; Zhang W; Liu GH
    Protein Cell; 2016 Jul; 7(7):478-88. PubMed ID: 27271327
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel mutation of the WRN gene in a Chinese patient with Werner syndrome.
    Zhao N; Hao F; Qu T; Zuo YG; Wang BX
    Clin Exp Dermatol; 2008 May; 33(3):278-81. PubMed ID: 18205852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue.
    Massip L; Garand C; Turaga RV; Deschênes F; Thorin E; Lebel M
    Exp Gerontol; 2006 Feb; 41(2):157-68. PubMed ID: 16330174
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.