309 related articles for article (PubMed ID: 26522624)
21. Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.
Maresca A; Supuran CT
Bioorg Med Chem Lett; 2010 Aug; 20(15):4511-4. PubMed ID: 20580555
[TBL] [Abstract][Full Text] [Related]
22. Carbonic anhydrase inhibitors: the very weak inhibitors dithiothreitol, beta-mercaptoethanol, tris(carboxyethyl)phosphine and threitol interfere with the binding of sulfonamides to isozymes II and IX.
Innocenti A; Hilvo M; Scozzafava A; Lindfors M; Nordlund HR; Kulomaa MS; Parkkila S; Supuran CT
Bioorg Med Chem Lett; 2008 Mar; 18(6):1898-903. PubMed ID: 18295485
[TBL] [Abstract][Full Text] [Related]
23. Carbonic anhydrase inhibitors: transepithelial transport of thioureido sulfonamide inhibitors of the cancer-associated isozyme IX is dependent on efflux transporters.
Vullo D; Steffansen B; Brodin B; Supuran CT; Scozzafava A; Nielsen CU
Bioorg Med Chem; 2006 Apr; 14(7):2418-27. PubMed ID: 16321542
[TBL] [Abstract][Full Text] [Related]
24. Saccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.
Mahon BP; Hendon AM; Driscoll JM; Rankin GM; Poulsen SA; Supuran CT; McKenna R
Bioorg Med Chem; 2015 Feb; 23(4):849-54. PubMed ID: 25614109
[TBL] [Abstract][Full Text] [Related]
25. Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates.
Moeker J; Mahon BP; Bornaghi LF; Vullo D; Supuran CT; McKenna R; Poulsen SA
J Med Chem; 2014 Oct; 57(20):8635-45. PubMed ID: 25254302
[TBL] [Abstract][Full Text] [Related]
26. Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.
Winum JY; Vullo D; Casini A; Montero JL; Scozzafava A; Supuran CT
J Med Chem; 2003 Dec; 46(25):5471-7. PubMed ID: 14640555
[TBL] [Abstract][Full Text] [Related]
27. Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes.
Moeker J; Peat TS; Bornaghi LF; Vullo D; Supuran CT; Poulsen SA
J Med Chem; 2014 Apr; 57(8):3522-31. PubMed ID: 24689792
[TBL] [Abstract][Full Text] [Related]
28. Glycosidic carbonic anhydrase IX inhibitors: a sweet approach against cancer.
Winum JY; Colinas PA; Supuran CT
Bioorg Med Chem; 2013 Mar; 21(6):1419-26. PubMed ID: 23199483
[TBL] [Abstract][Full Text] [Related]
29. Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.
Garaj V; Puccetti L; Fasolis G; Winum JY; Montero JL; Scozzafava A; Vullo D; Innocenti A; Supuran CT
Bioorg Med Chem Lett; 2005 Jun; 15(12):3102-8. PubMed ID: 15905091
[TBL] [Abstract][Full Text] [Related]
30. Selective inhibition of carbonic anhydrase IX decreases cell proliferation and induces ceramide-mediated apoptosis in human cancer cells.
Cianchi F; Vinci MC; Supuran CT; Peruzzi B; De Giuli P; Fasolis G; Perigli G; Pastorekova S; Papucci L; Pini A; Masini E; Puccetti L
J Pharmacol Exp Ther; 2010 Sep; 334(3):710-9. PubMed ID: 20519553
[TBL] [Abstract][Full Text] [Related]
31. Intrinsic thermodynamics of inhibitor binding to human carbonic anhydrase IX.
Linkuvienė V; Matulienė J; Juozapaitienė V; Michailovienė V; Jachno J; Matulis D
Biochim Biophys Acta; 2016 Apr; 1860(4):708-18. PubMed ID: 26794023
[TBL] [Abstract][Full Text] [Related]
32. Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.
Gitto R; Agnello S; Ferro S; De Luca L; Vullo D; Brynda J; Mader P; Supuran CT; Chimirri A
J Med Chem; 2010 Mar; 53(6):2401-8. PubMed ID: 20170095
[TBL] [Abstract][Full Text] [Related]
33. Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII.
Alafeefy AM; Isik S; Abdel-Aziz HA; Ashour AE; Vullo D; Al-Jaber NA; Supuran CT
Bioorg Med Chem; 2013 Mar; 21(6):1396-403. PubMed ID: 23290254
[TBL] [Abstract][Full Text] [Related]
34. 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.
Leitans J; Sprudza A; Tanc M; Vozny I; Zalubovskis R; Tars K; Supuran CT
Bioorg Med Chem; 2013 Sep; 21(17):5130-8. PubMed ID: 23859774
[TBL] [Abstract][Full Text] [Related]
35. Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
Knaus EE; Innocenti A; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2011 Oct; 21(19):5892-6. PubMed ID: 21852133
[TBL] [Abstract][Full Text] [Related]
36. Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.
Almajan GL; Innocenti A; Puccetti L; Manole G; Barbuceanu S; Saramet I; Scozzafava A; Supuran CT
Bioorg Med Chem Lett; 2005 May; 15(9):2347-52. PubMed ID: 15837323
[TBL] [Abstract][Full Text] [Related]
37. Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX.
Sharma A; Tiwari M; Supuran CT
J Enzyme Inhib Med Chem; 2014 Apr; 29(2):292-6. PubMed ID: 23488741
[TBL] [Abstract][Full Text] [Related]
38. Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides.
Akdemir A; Güzel-Akdemir O; Scozzafava A; Capasso C; Supuran CT
Bioorg Med Chem; 2013 Sep; 21(17):5228-32. PubMed ID: 23842519
[TBL] [Abstract][Full Text] [Related]
39. Inhibition of carbonic anhydrase IX: a new strategy against cancer.
Winum JY; Scozzafava A; Montero JL; Supuran CT
Anticancer Agents Med Chem; 2009 Jul; 9(6):693-702. PubMed ID: 19601749
[TBL] [Abstract][Full Text] [Related]
40. Dissecting the inhibition mechanism of cytosolic versus transmembrane carbonic anhydrases by ESR.
Ciani L; Cecchi A; Temperini C; Supuran CT; Ristori S
J Phys Chem B; 2009 Oct; 113(42):13998-4005. PubMed ID: 19778001
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]