BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

873 related articles for article (PubMed ID: 26524520)

  • 1. Conformational control of DNA target cleavage by CRISPR-Cas9.
    Sternberg SH; LaFrance B; Kaplan M; Doudna JA
    Nature; 2015 Nov; 527(7576):110-3. PubMed ID: 26524520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9.
    Palermo G; Ricci CG; Fernando A; Basak R; Jinek M; Rivalta I; Batista VS; McCammon JA
    J Am Chem Soc; 2017 Nov; 139(45):16028-16031. PubMed ID: 28764328
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
    Sternberg SH; Redding S; Jinek M; Greene EC; Doudna JA
    Nature; 2014 Mar; 507(7490):62-7. PubMed ID: 24476820
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition Mechanism of an Anti-CRISPR Suppressor AcrIIA4 Targeting SpyCas9.
    Yang H; Patel DJ
    Mol Cell; 2017 Jul; 67(1):117-127.e5. PubMed ID: 28602637
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Probing the structural dynamics of the CRISPR-Cas9 RNA-guided DNA-cleavage system by coarse-grained modeling.
    Zheng W
    Proteins; 2017 Feb; 85(2):342-353. PubMed ID: 27936513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nucleic Acid-Dependent Conformational Changes in CRISPR-Cas9 Revealed by Site-Directed Spin Labeling.
    Vazquez Reyes C; Tangprasertchai NS; Yogesha SD; Nguyen RH; Zhang X; Rajan R; Qin PZ
    Cell Biochem Biophys; 2017 Jun; 75(2):203-210. PubMed ID: 27342128
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
    Jiang F; Taylor DW; Chen JS; Kornfeld JE; Zhou K; Thompson AJ; Nogales E; Doudna JA
    Science; 2016 Feb; 351(6275):867-71. PubMed ID: 26841432
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
    Yamano T; Zetsche B; Ishitani R; Zhang F; Nishimasu H; Nureki O
    Mol Cell; 2017 Aug; 67(4):633-645.e3. PubMed ID: 28781234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.
    Babu K; Kathiresan V; Kumari P; Newsom S; Parameshwaran HP; Chen X; Liu J; Qin PZ; Rajan R
    Biochemistry; 2021 Dec; 60(49):3783-3800. PubMed ID: 34757726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
    Swarts DC; van der Oost J; Jinek M
    Mol Cell; 2017 Apr; 66(2):221-233.e4. PubMed ID: 28431230
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Programmable RNA recognition and cleavage by CRISPR/Cas9.
    O'Connell MR; Oakes BL; Sternberg SH; East-Seletsky A; Kaplan M; Doudna JA
    Nature; 2014 Dec; 516(7530):263-6. PubMed ID: 25274302
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
    Pausch P; Müller-Esparza H; Gleditzsch D; Altegoer F; Randau L; Bange G
    Mol Cell; 2017 Aug; 67(4):622-632.e4. PubMed ID: 28781236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9.
    Dagdas YS; Chen JS; Sternberg SH; Doudna JA; Yildiz A
    Sci Adv; 2017 Aug; 3(8):eaao0027. PubMed ID: 28808686
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural insights into DNA cleavage activation of CRISPR-Cas9 system.
    Huai C; Li G; Yao R; Zhang Y; Cao M; Kong L; Jia C; Yuan H; Chen H; Lu D; Huang Q
    Nat Commun; 2017 Nov; 8(1):1375. PubMed ID: 29123204
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRISPR-Cas9 Structures and Mechanisms.
    Jiang F; Doudna JA
    Annu Rev Biophys; 2017 May; 46():505-529. PubMed ID: 28375731
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a).
    Singh D; Mallon J; Poddar A; Wang Y; Tippana R; Yang O; Bailey S; Ha T
    Proc Natl Acad Sci U S A; 2018 May; 115(21):5444-5449. PubMed ID: 29735714
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.
    Fonfara I; Richter H; Bratovič M; Le Rhun A; Charpentier E
    Nature; 2016 Apr; 532(7600):517-21. PubMed ID: 27096362
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Guide RNA functional modules direct Cas9 activity and orthogonality.
    Briner AE; Donohoue PD; Gomaa AA; Selle K; Slorach EM; Nye CH; Haurwitz RE; Beisel CL; May AP; Barrangou R
    Mol Cell; 2014 Oct; 56(2):333-339. PubMed ID: 25373540
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target.
    Anders C; Niewoehner O; Jinek M
    Methods Enzymol; 2015; 558():515-537. PubMed ID: 26068752
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation.
    Mekler V; Minakhin L; Severinov K
    Proc Natl Acad Sci U S A; 2017 May; 114(21):5443-5448. PubMed ID: 28484024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.